Dietary salt promotes cognitive impairment through tau phosphorylation G Faraco, K Hochrainer, SG Segarra, S Schaeffer, MM Santisteban, ... Nature 574 (7780), 686-690, 2019 | 179 | 2019 |
The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects K Hochrainer, H Mayer, U Baranyi, BR Binder, J Lipp, R Kroismayr Genomics 85 (2), 153-164, 2005 | 140 | 2005 |
Nuclear factor-κB activation and postischemic inflammation are suppressed in CD36-null mice after middle cerebral artery occlusion A Kunz, T Abe, K Hochrainer, M Shimamura, J Anrather, G Racchumi, ... Journal of Neuroscience 28 (7), 1649-1658, 2008 | 123 | 2008 |
Tau induces PSD95–neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration L Park, K Hochrainer, Y Hattori, SJ Ahn, A Anfray, G Wang, K Uekawa, ... Nature neuroscience 23 (9), 1079-1089, 2020 | 100 | 2020 |
Site-specific phosphorylation of the p65 protein subunit mediates selective gene expression by differential NF-κB and RNA polymerase II promoter recruitment K Hochrainer, G Racchumi, J Anrather Journal of Biological Chemistry 288 (1), 285-293, 2013 | 96 | 2013 |
Progranulin deficiency promotes post-ischemic blood–brain barrier disruption K Jackman, T Kahles, D Lane, L Garcia-Bonilla, T Abe, C Capone, ... Journal of Neuroscience 33 (50), 19579-19589, 2013 | 95 | 2013 |
Cerebral ischemia induces the aggregation of proteins linked to neurodegenerative diseases A Kahl, I Blanco, K Jackman, J Baskar, H Milaganur Mohan, ... Scientific Reports 8 (1), 2701, 2018 | 85 | 2018 |
Reperfusion rather than ischemia drives the formation of ubiquitin aggregates after middle cerebral artery occlusion K Hochrainer, K Jackman, J Anrather, C Iadecola Stroke 43 (8), 2229-2235, 2012 | 55 | 2012 |
Highly homologous HERC proteins localize to endosomes and exhibit specific interactions with hPLIC and Nm23B K Hochrainer, R Kroismayr, U Baranyi, BR Binder, J Lipp Cellular and molecular life sciences 65, 2105-2117, 2008 | 47 | 2008 |
Phosphatidylethanolamine critically supports internalization of cell-penetrating protein C inhibitor P Baumgärtner, M Geiger, S Zieseniss, J Malleier, JA Huntington, ... The Journal of cell biology 179 (4), 793-804, 2007 | 44 | 2007 |
Regulation of nuclear factor κB (NF-κB) transcriptional activity via p65 acetylation by the chaperonin containing TCP1 (CCT) N Pejanovic, K Hochrainer, T Liu, BL Aerne, MP Soares, J Anrather Public Library of Science 7 (7), e42020, 2012 | 36 | 2012 |
Crosstalk between the NF‐κB activating IKK‐complex and the CSN signalosome L Orel, H Neumeier, K Hochrainer, BR Binder, JA Schmid Journal of Cellular and Molecular Medicine 14 (6b), 1555-1568, 2010 | 35 | 2010 |
Protein modifications with ubiquitin as response to cerebral ischemia-reperfusion injury K Hochrainer Translational stroke research 9 (2), 157-173, 2018 | 34 | 2018 |
The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation K Hochrainer, N Pejanovic, VA Olaseun, S Zhang, C Iadecola, J Anrather Nucleic acids research 43 (20), 9889-9904, 2015 | 34 | 2015 |
Monoubiquitination of nuclear RelA negatively regulates NF-κB activity independent of proteasomal degradation K Hochrainer, G Racchumi, S Zhang, C Iadecola, J Anrather Cellular and Molecular Life Sciences 69, 2057-2073, 2012 | 34 | 2012 |
Stroke proteomics: from discovery to diagnostic and therapeutic applications K Hochrainer, W Yang Circulation research 130 (8), 1145-1166, 2022 | 29 | 2022 |
SUMO2/3 is associated with ubiquitinated protein aggregates in the mouse neocortex after middle cerebral artery occlusion K Hochrainer, K Jackman, C Benakis, J Anrather, C Iadecola Journal of Cerebral Blood Flow & Metabolism 35 (1), 1-5, 2015 | 27 | 2015 |
Lipoprotein Receptor–Related Protein-6 Protects the Brain From Ischemic Injury T Abe, P Zhou, K Jackman, C Capone, B Casolla, K Hochrainer, T Kahles, ... Stroke 44 (8), 2284-2291, 2013 | 25 | 2013 |
Hypo-phosphorylation leads to nuclear retention of NF-κB p65 due to impaired IκBα gene synthesis K Hochrainer, G Racchumi, J Anrather FEBS letters 581 (28), 5493-5499, 2007 | 23 | 2007 |
Ubiquitylation within signaling pathways in-and outside of inflammation K Hochrainer, J Lipp Thrombosis and haemostasis 97 (03), 370-377, 2007 | 23 | 2007 |