| Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group Lancet (London, England) 397 (10285), 1637, 2021 | 2275* | 2021 |
| Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study RJ Allen, J Porte, R Braybrooke, C Flores, TE Fingerlin, JM Oldham, ... The Lancet respiratory medicine 5 (11), 869-880, 2017 | 268 | 2017 |
| IL-13-induced airway hyperreactivity during respiratory syncytial virus infection is STAT6 dependent KK Tekkanat, HF Maassab, DS Cho, JJ Lai, A John, A Berlin, MH Kaplan, ... The Journal of Immunology 166 (5), 3542-3548, 2001 | 189 | 2001 |
| Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue JA Aguiar, BJM Tremblay, MJ Mansfield, O Woody, B Lobb, A Banerjee, ... European Respiratory Journal 56 (3), 2020 | 182 | 2020 |
| Novel blood pressure locus and gene discovery using genome-wide association study and expression data sets from blood and the kidney LV Wain, A Vaez, R Jansen, R Joehanes, PJ Van Der Most, ... Hypertension 70 (3), e4-e19, 2017 | 180 | 2017 |
| COVID‐19 and pulmonary fibrosis: A potential role for lung epithelial cells and fibroblasts AE John, C Joseph, G Jenkins, AL Tatler Immunological reviews 302 (1), 228-240, 2021 | 171 | 2021 |
| Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma AL Tatler, AE John, L Jolly, A Habgood, J Porte, C Brightling, AJ Knox, ... The Journal of Immunology 187 (11), 6094-6107, 2011 | 153 | 2011 |
| Extracellular matrix cross-linking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis CJ Philp, I Siebeke, D Clements, S Miller, A Habgood, AE John, ... American journal of respiratory cell and molecular biology 58 (5), 594-603, 2018 | 150 | 2018 |
| Fractalkine has anti-apoptotic and proliferative effects on human vascular smooth muscle cells via epidermal growth factor receptor signalling GE White, TCC Tan, AE John, C Whatling, WL McPheat, DR Greaves Cardiovascular research 85 (4), 825-835, 2010 | 148 | 2010 |
| Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis AE John, JC Luckett, AL Tatler, RO Awais, A Desai, A Habgood, ... Journal of Nuclear Medicine 54 (12), 2146-2152, 2013 | 113 | 2013 |
| Respiratory syncytial virus‐induced CCL5/RANTES contributes to exacerbation of allergic airway inflammation AE John, AA Berlin, NW Lukacs European journal of immunology 33 (6), 1677-1685, 2003 | 113 | 2003 |
| The duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization A Chakera, RM Seeber, AE John, KA Eidne, DR Greaves Molecular pharmacology 73 (5), 1362-1370, 2008 | 105 | 2008 |
| Discovery of a potent nanoparticle P-selectin antagonist with anti-inflammatory effects in allergic airway disease AE John, NW Lukacs, AA Berlin, A Palecanda, RF Bargatze, LM Stoolman, ... The FASEB journal: official publication of the Federation of American …, 2003 | 105 | 2003 |
| Human airway smooth muscle cells from asthmatic individuals have CXCL8 hypersecretion due to increased NF-κB p65, C/EBPβ, and RNA polymerase II binding to the CXCL8 promoter AE John, YM Zhu, CE Brightling, L Pang, AJ Knox The Journal of Immunology 183 (7), 4682-4692, 2009 | 98 | 2009 |
| Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis AE John, RH Graves, KT Pun, G Vitulli, EJ Forty, PF Mercer, JL Morrell, ... Nature Communications 11 (1), 4659, 2020 | 81 | 2020 |
| E-and P-selectins are essential for the development of cockroach allergen-induced airway responses NW Lukacs, A John, A Berlin, DC Bullard, R Knibbs, LM Stoolman The Journal of Immunology 169 (4), 2120-2125, 2002 | 73 | 2002 |
| Temporal production of CCL28 corresponds to eosinophil accumulation and airway hyperreactivity in allergic airway inflammation AE John, MS Thomas, AA Berlin, NW Lukacs The American journal of pathology 166 (2), 345-353, 2005 | 69 | 2005 |
| CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET RL Clifford, JK Patel, AE John, AL Tatler, L Mazengarb, CE Brightling, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 308 (9 …, 2015 | 65 | 2015 |
| Abnormal histone methylation is responsible for increased vascular endothelial growth factor 165a secretion from airway smooth muscle cells in asthma RL Clifford, AE John, CE Brightling, AJ Knox The Journal of Immunology 189 (2), 819-831, 2012 | 63 | 2012 |
| Amplification of TGFβ induced ITGB6 gene transcription may promote pulmonary fibrosis AL Tatler, AT Goodwin, O Gbolahan, G Saini, J Porte, AE John, RL Clifford, ... PloS one 11 (8), e0158047, 2016 | 45 | 2016 |
