Sleep drives metabolite clearance from the adult brain L Xie, H Kang, Q Xu, MJ Chen, Y Liao, M Thiyagarajan, J O’Donnell, ... science 342 (6156), 373-377, 2013 | 4916 | 2013 |
A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β JJ Iliff, M Wang, Y Liao, BA Plogg, W Peng, GA Gundersen, H Benveniste, ... Science translational medicine 4 (147), 147ra111-147ra111, 2012 | 4870 | 2012 |
Impairment of paravascular clearance pathways in the aging brain BT Kress, JJ Iliff, M Xia, M Wang, HS Wei, D Zeppenfeld, L Xie, H Kang, ... Annals of neurology 76 (6), 845-861, 2014 | 1222 | 2014 |
Cerebral arterial pulsation drives paravascular CSF–interstitial fluid exchange in the murine brain JJ Iliff, M Wang, DM Zeppenfeld, A Venkataraman, BA Plog, Y Liao, ... Journal of Neuroscience 33 (46), 18190-18199, 2013 | 1103 | 2013 |
Brain-wide pathway for waste clearance captured by contrast-enhanced MRI JJ Iliff, H Lee, M Yu, T Feng, J Logan, M Nedergaard, H Benveniste The Journal of clinical investigation 123 (3), 1299-1309, 2013 | 1059 | 2013 |
Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury JJ Iliff, MJ Chen, BA Plog, DM Zeppenfeld, M Soltero, L Yang, I Singh, ... Journal of Neuroscience 34 (49), 16180-16193, 2014 | 978 | 2014 |
Aquaporin-4-dependent glymphatic solute transport in the rodent brain H Mestre, LM Hablitz, ALR Xavier, W Feng, W Zou, T Pu, H Monai, ... Elife 7, e40070, 2018 | 488 | 2018 |
Association of perivascular localization of aquaporin-4 with cognition and Alzheimer disease in aging brains DM Zeppenfeld, M Simon, JD Haswell, D D’Abreo, C Murchison, JF Quinn, ... JAMA neurology 74 (1), 91-99, 2017 | 453 | 2017 |
Is there a cerebral lymphatic system? JJ Iliff, M Nedergaard Stroke 44 (6_suppl_1), S93-S95, 2013 | 415 | 2013 |
Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer L Yang, BT Kress, HJ Weber, M Thiyagarajan, B Wang, R Deane, ... Journal of translational medicine 11, 1-9, 2013 | 333 | 2013 |
Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease MJ Simon, JJ Iliff Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (3), 442-451, 2016 | 330 | 2016 |
‘Hit & Run’model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation Z Ren, JJ Iliff, L Yang, J Yang, X Chen, MJ Chen, RN Giese, B Wang, ... Journal of Cerebral Blood Flow & Metabolism 33 (6), 834-845, 2013 | 313 | 2013 |
The spectrum of neurobehavioral sequelae after repetitive mild traumatic brain injury: a novel mouse model of chronic traumatic encephalopathy AL Petraglia, BA Plog, S Dayawansa, M Chen, ML Dashnaw, ... Journal of neurotrauma 31 (13), 1211-1224, 2014 | 239 | 2014 |
Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain VR Thrane, AS Thrane, BA Plog, M Thiyagarajan, JJ Iliff, R Deane, ... Scientific reports 3 (1), 2582, 2013 | 193 | 2013 |
Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia W Zhang, T Otsuka, N Sugo, A Ardeshiri, YK Alhadid, JJ Iliff, AE DeBarber, ... Stroke 39 (7), 2073-2078, 2008 | 188 | 2008 |
Implications of the discovery of brain lymphatic pathways. JJ Iliff, SA Goldman, M Nedergaard The Lancet. Neurology 14 (10), 977-979, 2015 | 186 | 2015 |
The pathophysiology underlying repetitive mild traumatic brain injury in a novel mouse model of chronic traumatic encephalopathy AL Petraglia, BA Plog, S Dayawansa, ML Dashnaw, K Czerniecka, ... Surgical neurology international 5, 2014 | 161 | 2014 |
Focal solute trapping and global glymphatic pathway impairment in a murine model of multiple microinfarcts M Wang, F Ding, SY Deng, X Guo, W Wang, JJ Iliff, M Nedergaard Journal of Neuroscience 37 (11), 2870-2877, 2017 | 159 | 2017 |
The emerging relationship between interstitial fluid–cerebrospinal fluid exchange, amyloid-β, and sleep EL Boespflug, JJ Iliff Biological psychiatry 83 (4), 328-336, 2018 | 157 | 2018 |
Cognitive deficits and delayed neuronal loss in a mouse model of multiple microinfarcts M Wang, JJ Iliff, Y Liao, MJ Chen, MS Shinseki, A Venkataraman, ... Journal of Neuroscience 32 (50), 17948-17960, 2012 | 156 | 2012 |