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John Giudicessi
John Giudicessi
Assistant Professor of Medicine and Pharmacology; Mayo Clinic
在 mayo.edu 的电子邮件经过验证 - 首页
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Urgent guidance for navigating and circumventing the QTc-prolonging and torsadogenic potential of possible pharmacotherapies for coronavirus disease 19 (COVID-19)
JR Giudicessi, PA Noseworthy, PA Friedman, MJ Ackerman
Mayo Clinic Proceedings 95 (6), 1213-1221, 2020
4872020
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
DE Arking, SL Pulit, L Crotti, P Van Der Harst, PB Munroe, TT Koopmann, ...
Nature genetics 46 (8), 826-836, 2014
3242014
Transient outward current (Ito) gain-of-function mutations in the KCND3-encoded Kv4. 3 potassium channel and Brugada syndrome
JR Giudicessi, D Ye, DJ Tester, L Crotti, A Mugione, VV Nesterenko, ...
Heart rhythm 8 (7), 1024-1032, 2011
2742011
Spectrum and prevalence of mutations involving BrS1-through BrS12-susceptibility genes in a cohort of unrelated patients referred for Brugada syndrome genetic testing …
L Crotti, CA Marcou, DJ Tester, S Castelletti, JR Giudicessi, M Torchio, ...
Journal of the American College of Cardiology 60 (15), 1410-1418, 2012
2352012
Determinants of incomplete penetrance and variable expressivity in heritable cardiac arrhythmia syndromes
JR Giudicessi, MJ Ackerman
Translational Research 161 (1), 1-14, 2013
2312013
European heart rhythm association (EHRA)/heart rhythm society (HRS)/Asia pacific heart rhythm society (APHRS)/latin American heart rhythm society (LAHRS) expert consensus …
AAM Wilde, C Semsarian, MF Márquez, AS Shamloo, MJ Ackerman, ...
Europace 24 (8), 1307-1367, 2022
2112022
Genotype-and phenotype-guided management of congenital long QT syndrome
JR Giudicessi, MJ Ackerman
Current problems in cardiology 38 (10), 417-455, 2013
1922013
Variants in the 3′ untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an …
AS Amin, JR Giudicessi, AJ Tijsen, AM Spanjaart, YJ Reckman, ...
European heart journal 33 (6), 714-723, 2012
1732012
The genetic architecture of long QT syndrome: a critical reappraisal
JR Giudicessi, AAM Wilde, MJ Ackerman
Trends in cardiovascular medicine 28 (7), 453-464, 2018
1402018
Potassium-channel mutations and cardiac arrhythmias—diagnosis and therapy
JR Giudicessi, MJ Ackerman
Nature Reviews Cardiology 9 (6), 319-332, 2012
1382012
Exome Sequencing and Systems Biology Converge to Identify Novel Mutations in the L-Type Calcium Channel, CACNA1C, Linked to Autosomal Dominant Long …
NJ Boczek, JM Best, DJ Tester, JR Giudicessi, S Middha, JM Evans, ...
Circulation: Cardiovascular Genetics 6 (3), 279-289, 2013
1262013
Enhanced Classification of Brugada Syndrome–Associated and Long-QT Syndrome–Associated Genetic Variants in the SCN5A-Encoded Nav1.5 Cardiac Sodium …
JD Kapplinger, JR Giudicessi, D Ye, DJ Tester, TE Callis, CR Valdivia, ...
Circulation: Cardiovascular Genetics 8 (4), 582-595, 2015
1022015
Artificial intelligence–enabled assessment of the heart rate corrected QT interval using a mobile electrocardiogram device
JR Giudicessi, M Schram, JM Bos, CD Galloway, JB Shreibati, ...
Circulation 143 (13), 1274-1286, 2021
1012021
Genetic susceptibility for COVID-19–associated sudden cardiac death in African Americans
JR Giudicessi, DM Roden, AAM Wilde, MJ Ackerman
Heart rhythm 17 (9), 1487-1492, 2020
1012020
Classification and reporting of potentially proarrhythmic common genetic variation in long QT syndrome genetic testing
JR Giudicessi, DM Roden, AAM Wilde, MJ Ackerman
Circulation 137 (6), 619-630, 2018
872018
Novel mutations in the KCND3‐encoded Kv4.3 K+ channel associated with autopsy‐negative sudden unexplained death
JR Giudicessi, D Ye, CJ Kritzberger, VV Nesterenko, DJ Tester, ...
Human mutation 33 (6), 989-997, 2012
792012
Cardiovascular safety of prokinetic agents: a focus on drug‐induced arrhythmias
JR Giudicessi, MJ Ackerman, M Camilleri
Neurogastroenterology & Motility 30 (6), e13302, 2018
672018
Precision cardiovascular medicine: state of genetic testing
JR Giudicessi, IJ Kullo, MJ Ackerman
Mayo Clinic Proceedings 92 (4), 642-662, 2017
662017
Phylogenetic and physicochemical analyses enhance the classification of rare nonsynonymous single nucleotide variants in type 1 and 2 long-QT syndrome
JR Giudicessi, JD Kapplinger, DJ Tester, M Alders, BA Salisbury, ...
Circulation: Cardiovascular Genetics 5 (5), 519-528, 2012
652012
Characterization of SEMA3A-Encoded Semaphorin as a Naturally Occurring Kv4.3 Protein Inhibitor and its Contribution to Brugada Syndrome
NJ Boczek, D Ye, EK Johnson, W Wang, L Crotti, DJ Tester, F Dagradi, ...
Circulation research 115 (4), 460-469, 2014
632014
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