| The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1α L Zhong, A D'Urso, D Toiber, C Sebastian, RE Henry, DD Vadysirisack, ... Cell 140 (2), 280-293, 2010 | 1124 | 2010 |
| SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine H Jiang, S Khan, Y Wang, G Charron, B He, C Sebastian, J Du, R Kim, ... Nature 496 (7443), 110-113, 2013 | 754 | 2013 |
| The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism C Sebastián, BMM Zwaans, DM Silberman, M Gymrek, A Goren, L Zhong, ... Cell 151 (6), 1185-1199, 2012 | 702 | 2012 |
| SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling D Toiber, F Erdel, K Bouazoune, DM Silberman, L Zhong, P Mulligan, ... Molecular cell 51 (4), 454-468, 2013 | 385 | 2013 |
| Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism S Masri, P Rigor, M Cervantes, N Ceglia, C Sebastian, C Xiao, ... Cell 158 (3), 659-672, 2014 | 293 | 2014 |
| SIRT6 suppresses pancreatic cancer through control of Lin28b S Kugel, C Sebastián, J Fitamant, KN Ross, SK Saha, E Jain, A Gladden, ... Cell 165 (6), 1401-1415, 2016 | 264 | 2016 |
| From sirtuin biology to human diseases: an update C Sebastián, FK Satterstrom, MC Haigis, R Mostoslavsky Journal of Biological Chemistry 287 (51), 42444-42452, 2012 | 264 | 2012 |
| Metabolic pathways regulating colorectal cancer initiation and progression S La Vecchia, C Sebastián Seminars in cell & developmental biology 98, 63-70, 2020 | 253 | 2020 |
| Immunosenescence of macrophages: reduced MHC class II gene expression C Herrero, C Sebastián, L Marqués, M Comalada, J Xaus, AF Valledor, ... Experimental gerontology 37 (2-3), 389-394, 2002 | 142 | 2002 |
| MacrophAging: a cellular and molecular review C Sebastián, M Espia, M Serra, A Celada, J Lloberas Immunobiology 210 (2-4), 121-126, 2005 | 115 | 2005 |
| Regulation of murine Tap1 and Lmp2 genes in macrophages by interferon gamma is mediated by STAT1 and IRF-1 M Brucet, L Marques, C Sebastian, J Lloberas, A Celada Genes & Immunity 5 (1), 26-35, 2004 | 109 | 2004 |
| Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction F Montecucco, I Bauer, V Braunersreuther, S Bruzzone, A Akhmedov, ... Antioxidants & redox signaling 18 (6), 630-641, 2013 | 105 | 2013 |
| Telomere shortening and oxidative stress in aged macrophages results in impaired STAT5a phosphorylation C Sebastián, C Herrero, M Serra, J Lloberas, MA Blasco, A Celada The Journal of Immunology 183 (4), 2356-2364, 2009 | 95 | 2009 |
| High mobility group protein-mediated transcription requires DNA damage marker γ-H2AX I Singh, N Ozturk, J Cordero, A Mehta, D Hasan, C Cosentino, ... Cell research 25 (7), 837-850, 2015 | 89 | 2015 |
| Identification of and molecular basis for SIRT6 loss-of-function point mutations in cancer S Kugel, JL Feldman, MA Klein, DM Silberman, C Sebastián, C Mermel, ... Cell reports 13 (3), 479-488, 2015 | 79 | 2015 |
| Sox2 suppresses gastric tumorigenesis in mice A Sarkar, AJ Huebner, R Sulahian, A Anselmo, X Xu, K Flattery, N Desai, ... Cell reports 16 (7), 1929-1941, 2016 | 78 | 2016 |
| Deacetylase activity is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells C Sebastián, M Serra, A Yeramian, N Serrat, J Lloberas, A Celada The Journal of Immunology 180 (9), 5898-5906, 2008 | 62 | 2008 |
| SIRT6 suppresses cancer stem-like capacity in tumors with PI3K activation independently of its deacetylase activity RM Ioris, M Galie, G Ramadori, JG Anderson, A Charollais, ... Cell reports 18 (8), 1858-1868, 2017 | 55 | 2017 |
| Characterization of nuclear sirtuins: molecular mechanisms and physiological relevance D Toiber, C Sebastian, R Mostoslavsky Histone Deacetylases: the Biology and Clinical Implication, 189-224, 2011 | 55 | 2011 |
| Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming MA Kowalik, E Puliga, L Cabras, P Sulas, A Petrelli, A Perra, ... Journal of hepatology 72 (6), 1159-1169, 2020 | 50 | 2020 |
