LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption J Luo, Z Yang, YU Ma, Z Yue, H Lin, G Qu, J Huang, W Dai, C Li, C Zheng, ... Nature medicine 22 (5), 539-546, 2016 | 331 | 2016 |
Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor α by inhibiting NF-κB signaling pathway C Li, Z Yang, C Zhai, W Qiu, D Li, Z Yi, L Wang, J Tang, M Qian, J Luo, ... Molecular cancer 9, 1-13, 2010 | 153 | 2010 |
Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer L D’Amico, S Mahajan, AH Capietto, Z Yang, A Zamani, B Ricci, ... Journal of Experimental Medicine 213 (5), 827-840, 2016 | 144 | 2016 |
Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy‐induced bone loss by regulating RANKL‐mediated NF‐κB and MAPK signaling pathways C Li, Z Yang, Z Li, Y Ma, L Zhang, C Zheng, W Qiu, X Wu, X Wang, H Li, ... Journal of Bone and Mineral Research 26 (3), 644-656, 2011 | 136 | 2011 |
Inhibition of breast cancer metastases by a novel inhibitor of TGFβ receptor 1 Y Fang, Y Chen, L Yu, C Zheng, Y Qi, Z Li, Z Yang, Y Zhang, T Shi, J Luo, ... Journal of the National Cancer Institute 105 (1), 47-58, 2013 | 103 | 2013 |
Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF‐κB signaling pathway in colon cancer cells Z Yang, C Li, X Wang, C Zhai, Z Yi, L Wang, B Liu, B Du, H Wu, X Guo, ... Journal of cellular physiology 225 (1), 266-275, 2010 | 103 | 2010 |
Caffeic acid 3, 4‐dihydroxy‐phenethyl ester suppresses receptor activator of NF‐κB ligand–induced osteoclastogenesis and prevents ovariectomy‐induced bone loss through … X Wu, Z Li, Z Yang, C Zheng, J Jing, Y Chen, X Ye, X Lian, W Qiu, F Yang, ... Journal of Bone and Mineral Research 27 (6), 1298-1308, 2012 | 80 | 2012 |
Synthesis and biological evaluation of novel tetrahydro-β-carboline derivatives as antitumor growth and metastasis agents through inhibiting the transforming growth factor-β … C Zheng, Y Fang, W Tong, G Li, H Wu, W Zhou, Q Lin, F Yang, Z Yang, ... Journal of medicinal chemistry 57 (3), 600-612, 2014 | 70 | 2014 |
LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells Z Yue, Z Yuan, L Zeng, Y Wang, L Lai, J Li, P Sun, X Xue, J Qi, Z Yang, ... The FASEB Journal 32 (5), 2422, 2018 | 68 | 2018 |
Plumbagin inhibits breast tumor bone metastasis and osteolysis by modulating the tumor-bone microenvironment Z Li, J Xiao, X Wu, W Li, Z Yang, J Xie, L Xu, X Cai, Z Lin, W Guo, J Luo, ... Current molecular medicine 12 (8), 967-981, 2012 | 44 | 2012 |
Stereoselective synthesis of some methyl-substituted steroid hormones and their in vitro cytotoxic activity against human gastric cancer cell line MGC-803 C Li, W Qiu, Z Yang, J Luo, F Yang, M Liu, J Xie, J Tang Steroids 75 (12), 859-869, 2010 | 35 | 2010 |
Tmem178 acts in a novel negative feedback loop targeting NFATc1 to regulate bone mass CE Decker, Z Yang, R Rimer, KH Park-Min, C Macaubas, ED Mellins, ... Proceedings of the National Academy of Sciences 112 (51), 15654-15659, 2015 | 34 | 2015 |
RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis Z Yue, X Niu, Z Yuan, Q Qin, W Jiang, L He, J Gao, Y Ding, Y Liu, Z Xu, ... The Journal of Clinical Investigation 132 (2), 2022 | 32 | 2022 |
Calcium homeostasis: a potential vicious cycle of bone metastasis in breast cancers Z Yang, Z Yue, X Ma, Z Xu Frontiers in oncology 10, 293, 2020 | 31 | 2020 |
Plcγ2/Tmem178 dependent pathway in myeloid cells modulates the pathogenesis of cytokine storm syndrome S Mahajan, CE Decker, Z Yang, D Veis, ED Mellins, R Faccio Journal of autoimmunity 100, 62-74, 2019 | 29 | 2019 |
Crystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs) JG Xu, C Huang, Z Yang, M Jin, P Fu, N Zhang, J Luo, D Li, M Liu, Y Zhou, ... Journal of Biological Chemistry 290 (4), 2455-2465, 2015 | 25 | 2015 |
Sin1/mTORC2 regulate B cell growth and metabolism by activating mTORC1 and Myc M Li, AS Lazorchak, X Ouyang, H Zhang, H Liu, OA Arojo, L Yan, J Jin, ... Cellular & molecular immunology 16 (9), 757-769, 2019 | 21 | 2019 |
Bortezomib inhibits giant cell tumor of bone through induction of cell apoptosis and inhibition of osteoclast recruitment, giant cell formation, and bone resorption L Xu, J Luo, R Jin, Z Yue, P Sun, Z Yang, X Yang, W Wan, J Zhang, S Li, ... Molecular Cancer Therapeutics 15 (5), 854-865, 2016 | 21 | 2016 |
Importance of the Conserved Carboxyl-Terminal CNOT1 Binding Domain to Tristetraprolin Activity In Vivo WS Lai, DJ Stumpo, ML Wells, A Gruzdev, SN Hicks, CO Nicholson, ... Molecular and cellular biology 39 (13), e00029-19, 2019 | 20 | 2019 |
Phospholipase Cγ1 (PLCγ1) controls osteoclast numbers via colony-stimulating factor 1 (CSF-1)-dependent diacylglycerol/β-catenin/cyclinD1 pathway Z Yang, S Kim, S Mahajan, A Zamani, R Faccio Journal of Biological Chemistry 292 (4), 1178-1186, 2017 | 19 | 2017 |