Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk W Zhu, JC Gregory, E Org, JA Buffa, N Gupta, Z Wang, L Li, X Fu, Y Wu, ... Cell 165 (1), 111-124, 2016 | 1774 | 2016 |
A cardiovascular disease-linked gut microbial metabolite acts via adrenergic receptors I Nemet, PP Saha, N Gupta, W Zhu, KA Romano, SM Skye, T Cajka, ... Cell 180 (5), 862-877. e22, 2020 | 499 | 2020 |
Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential Nature Medicine, 2018 | 464 | 2018 |
Targeted inhibition of gut microbial trimethylamine N-oxide production reduces renal tubulointerstitial fibrosis and functional impairment in a murine model of chronic kidney … N Gupta, JA Buffa, AB Roberts, N Sangwan, SM Skye, L Li, KJ Ho, ... Arteriosclerosis, thrombosis, and vascular biology 40 (5), 1239-1255, 2020 | 140 | 2020 |
Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N‐oxide‐generating pathway, modulates platelet responsiveness and thrombosis risk W Zhu, JA Buffa, Z Wang, M Warrier, R Schugar, DM Shih, N Gupta, ... Journal of Thrombosis and Haemostasis 16 (9), 1857-1872, 2018 | 126 | 2018 |
The artificial sweetener erythritol and cardiovascular event risk M Witkowski, I Nemet, H Alamri, J Wilcox, N Gupta, N Nimer, A Haghikia, ... Nature medicine 29 (3), 710-718, 2023 | 125 | 2023 |
Nonlethal Inhibition of Gut Microbial Trimethylamine N‐oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure CL Organ, Z Li, TE Sharp III, DJ Polhemus, N Gupta, TT Goodchild, ... Journal of the American Heart Association 9 (10), e016223, 2020 | 78 | 2020 |
Proteasome proteolysis supports stimulated platelet function and thrombosis N Gupta, W Li, B Willard, RL Silverstein, TM McIntyre Arteriosclerosis, thrombosis, and vascular biology 34 (1), 160-168, 2014 | 67 | 2014 |
Deubiquitinases modulate platelet proteome ubiquitination, aggregation, and thrombosis N Gupta, W Li, TM McIntyre Arteriosclerosis, thrombosis, and vascular biology 35 (12), 2657-2666, 2015 | 31 | 2015 |
Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation SJ Kim, S Bale, P Verma, Q Wan, F Ma, JE Gudjonsson, SL Hazen, ... Iscience 25 (7), 2022 | 8 | 2022 |
Xylitol is prothrombotic and associated with cardiovascular risk M Witkowski, I Nemet, XS Li, J Wilcox, M Ferrell, H Alamri, N Gupta, ... European Heart Journal, ehae244, 2024 | 7 | 2024 |
THE ORAL PROTEASOME INHIBITOR IXAZOMIB IN COMBINATION WITH MELPHALAN-PREDNISONE FOR PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA: PHASE 1/2 DOSE-ESCALATION STUDY (NCT01335685) JS Miguel, MA Gutierrez, I Spicka, MV Mateos, K Song, M Craig, J Blade, ... Haematologica 102, 111-112, 2017 | 2 | 2017 |
Ubiquitin-proteasome system modulates platelet function N Gupta Cleveland State University, 2014 | 2 | 2014 |
INHIBITION OF GUT MICROBIOTA-DEPENDENT TRIMETHYLAMINE N-OXIDE PRODUCTION RESCUES SYSTOLIC CARDIAC FUNCTION IN A MURINE MODEL OF RENAL DYSFUNCTION R Bhandari, N Gupta, I Nemet, S Cameron, S Hazen Journal of the American College of Cardiology 77 (18_Supplement_1), 3400-3400, 2021 | | 2021 |
Studies on the fusion of myeloma cells with spleen cells N Gupta NDRI, KARNAL, 1990 | | 1990 |
Y. Jia, N. Viswakarma, SE Crawford, J. Sarkar, M. Sambasiva Rao, WJ Karpus, YS Kanwar, Y.-J. Zhu, JK Reddy Early embryonic lethality of mice with disrupted transcription … AJ Taylor, CW Beck, A Khan, A Nakamoto, S Okamoto, M Tai, ... | | |
Gut Microbe-Derived Metabolite Trimethylamine N-Oxide Activates PERK to Drive Mesenchymal Differentiation and Fibrosis S Kim, S Bale, Q Wan, J Gudjonsson, SL Hazen, PW Harms, PS Tsou, ... Available at SSRN 3912949, 0 | | |