| Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity DE Lackey, CJ Lynch, KC Olson, R Mostaedi, M Ali, WH Smith, F Karpe, ... American Journal of Physiology-Endocrinology and Metabolism 304 (11), E1175 …, 2013 | 333 | 2013 |
| Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study KM Hastie, H Li, D Bedinger, SL Schendel, SM Dennison, K Li, ... Science 374 (6566), 472-478, 2021 | 269 | 2021 |
| Thermodynamic benchmark study using Biacore technology I Navratilova, GA Papalia, RL Rich, D Bedinger, S Brophy, B Condon, ... Analytical Biochemistry 364 (1), 67-77, 2007 | 119 | 2007 |
| A fully human, allosteric monoclonal antibody that activates the insulin receptor and improves glycemic control V Bhaskar, ID Goldfine, DH Bedinger, A Lau, HF Kuan, LM Gross, ... Diabetes 61 (5), 1263-1271, 2012 | 87 | 2012 |
| Metabolic, anabolic, and mitogenic insulin responses: a tissue-specific perspective for insulin receptor activators DH Bedinger, SH Adams Molecular and cellular endocrinology 415, 143-156, 2015 | 86 | 2015 |
| Discovery of diverse and functional antibodies from large human repertoire antibody libraries LJ Schwimmer, B Huang, H Giang, RL Cotter, DS Chemla-Vogel, FV Dy, ... Journal of immunological methods 391 (1-2), 60-71, 2013 | 61 | 2013 |
| Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets KH Ching, EJ Collarini, YN Abdiche, D Bedinger, D Pedersen, S Izquierdo, ... MAbs 10 (1), 71-80, 2018 | 60 | 2018 |
| Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1β activity MK Roell, H Issafras, RJ Bauer, KS Michelson, N Mendoza, SI Vanegas, ... Journal of Biological Chemistry 285 (27), 20607-20614, 2010 | 47 | 2010 |
| A natively paired antibody library yields drug leads with higher sensitivity and specificity than a randomly paired antibody library AS Adler, D Bedinger, MS Adams, MA Asensio, RC Edgar, R Leong, ... MAbs 10 (3), 431-443, 2018 | 37 | 2018 |
| Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms D Bedinger, L Lao, S Khan, S Lee, T Takeuchi, AM Mirza MAbs 8 (2), 389-404, 2016 | 37 | 2016 |
| Assessing the binding properties of the anti-PD-1 antibody landscape using label-free biosensors ME Brown, D Bedinger, A Lilov, P Rathanaswami, M Vásquez, S Durand, ... PLoS One 15 (3), e0229206, 2020 | 28 | 2020 |
| Differential pathway coupling of the activated insulin receptor drives signaling selectivity by XMetA, an allosteric partial agonist antibody DH Bedinger, ID Goldfine, JA Corbin, MK Roell, SH Adams Journal of Pharmacology and Experimental Therapeutics 353 (1), 35-43, 2015 | 26 | 2015 |
| Inhibition of insulin receptor function by a human, allosteric monoclonal antibody: a potential new approach for the treatment of hyperinsulinemic hypoglycemia JA Corbin, V Bhaskar, ID Goldfine, H Issafras, DH Bedinger, A Lau, ... MAbs 6 (1), 262-272, 2014 | 25 | 2014 |
| Selective allosteric antibodies to the insulin receptor for the treatment of hyperglycemic and hypoglycemic disorders H Issafras, DH Bedinger, JA Corbin, ID Goldfine, V Bhaskar, ML White, ... Journal of Diabetes Science and Technology 8 (4), 865-873, 2014 | 24 | 2014 |
| Improved glucose metabolism in vitro and in vivo by an allosteric monoclonal antibody that increases insulin receptor binding affinity JA Corbin, V Bhaskar, ID Goldfine, DH Bedinger, A Lau, K Michelson, ... PLoS One 9 (2), e88684, 2014 | 23 | 2014 |
| Structure-based design of a highly stable, covalently-linked SARS-CoV-2 spike trimer with improved structural properties and immunogenicity E Olmedillas, CJ Mann, W Peng, YT Wang, RD Avalos, D Bedinger, ... bioRxiv, 2021.05. 06.441046, 2021 | 22 | 2021 |
| Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium HM Callaway, KM Hastie, SL Schendel, H Li, X Yu, J Shek, T Buck, S Hui, ... Cell reports 42 (1), 2023 | 16 | 2023 |
| Acute treatment with XMetA activates hepatic insulin receptors and lowers blood glucose in normal mice DH Bedinger, DA Kieffer, ID Goldfine, MK Roell, SH Adams Journal of Cellular Biochemistry 116 (9), 2109-2119, 2015 | 6 | 2015 |
| A Novel anti-PTH1R receptor antagonist monoclonal antibody reverses hypercalcemia induced by PTH or PTHrP: a potential treatment of primary hyperparathyroidism and humoral … A Choppin, D Bedinger, R Hunt, C Tran, S Wijesuriya, R Cotter, E Pongo, ... Annual Meeting SAT 399, 2017 | 3 | 2017 |
| Impacting Humoral Hypercalcemia of Malignancy (HHM) and associated PTH1R-mediated morbidities: Characterization of an Anti-PTH1R antagonist monoclonal antibody to reverse … A Mirza, D Bedinger, R Hunt, EP Robyn Cotter AACR Annual Meeting LB-L306, 2015 | 1 | 2015 |
