A single autoimmune T cell receptor recognizes more than a million different peptides L Wooldridge, J Ekeruche-Makinde, H Van Den Berg, A Skowera, ... Journal of Biological Chemistry 287 (2), 1168-1177, 2012 | 503 | 2012 |
VDJdb: a curated database of T-cell receptor sequences with known antigen specificity M Shugay, DV Bagaev, IV Zvyagin, RM Vroomans, JC Crawford, G Dolton, ... Nucleic acids research 46 (D1), D419-D427, 2018 | 443 | 2018 |
VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium DV Bagaev, RMA Vroomans, J Samir, U Stervbo, C Rius, G Dolton, ... Nucleic Acids Research 48 (D1), D1057-D1062, 2020 | 334 | 2020 |
Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1 (vol 12, pg 125, 2020) MD Crowther, G Dolton, M Legut, ME Caillaud, A Lloyd, M Attaf, ... NATURE IMMUNOLOGY 21 (6), 695-695, 2020 | 242 | 2020 |
Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1 MD Crowther, G Dolton, M Legut, ME Caillaud, A Lloyd, M Attaf, ... Nature immunology 21 (2), 178-185, 2020 | 240 | 2020 |
Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination SV Pageon, T Tabarin, Y Yamamoto, Y Ma, PR Nicovich, JS Bridgeman, ... Proceedings of the National Academy of Sciences 113 (37), E5454-E5463, 2016 | 232 | 2016 |
CRISPR-mediated TCR replacement generates superior anticancer transgenic T cells M Legut, G Dolton, AA Mian, OG Ottmann, AK Sewell Blood, The Journal of the American Society of Hematology 131 (3), 311-322, 2018 | 222 | 2018 |
Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes AM Bulek, DK Cole, A Skowera, G Dolton, S Gras, F Madura, A Fuller, ... Nature immunology 13 (3), 283-289, 2012 | 215 | 2012 |
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity DK Cole, AM Bulek, G Dolton, AJ Schauenberg, B Szomolay, W Rittase, ... The Journal of clinical investigation 126 (6), 2191-2204, 2016 | 160 | 2016 |
More tricks with tetramers: a practical guide to staining T cells with peptide–MHC multimers G Dolton, K Tungatt, A Lloyd, V Bianchi, SM Theaker, A Trimby, ... Immunology 146 (1), 11-22, 2015 | 157 | 2015 |
β-Cell–specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure A Skowera, K Ladell, JE McLaren, G Dolton, KK Matthews, E Gostick, ... Diabetes 64 (3), 916-925, 2015 | 137 | 2015 |
Peptide length determines the outcome of TCR/peptide-MHCI engagement J Ekeruche-Makinde, JJ Miles, HA Van Den Berg, A Skowera, DK Cole, ... Blood, The Journal of the American Society of Hematology 121 (7), 1112-1123, 2013 | 116 | 2013 |
Comparison of peptide–major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells G Dolton, A Lissina, A Skowera, K Ladell, K Tungatt, E Jones, ... Clinical & Experimental Immunology 177 (1), 47-63, 2014 | 111 | 2014 |
Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection JJ Miles, AM Bulek, DK Cole, E Gostick, AJA Schauenburg, G Dolton, ... PLoS pathogens 6 (11), e1001198, 2010 | 102 | 2010 |
Peptide–MHC class I tetramers can fail to detect relevant functional T cell clonotypes and underestimate antigen-reactive T cell populations C Rius, M Attaf, K Tungatt, V Bianchi, M Legut, A Bovay, M Donia, ... The Journal of Immunology 200 (7), 2263-2279, 2018 | 92 | 2018 |
Metabolic Adaptation of Human CD4+ and CD8+ T-Cells to T-Cell Receptor-Mediated Stimulation N Jones, JG Cronin, G Dolton, S Panetti, AJ Schauenburg, SAE Galloway, ... Frontiers in immunology 8, 1516, 2017 | 85 | 2017 |
Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV MA Stacey, M Marsden, S Clare, G Dolton, G Stack, E Jones, ... Cell host & microbe 15 (4), 471-483, 2014 | 85 | 2014 |
VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2 M Goncharov, D Bagaev, D Shcherbinin, I Zvyagin, D Bolotin, PG Thomas, ... Nature methods 19 (9), 1017-1019, 2022 | 78 | 2022 |
Optimized peptide–MHC multimer protocols for detection and isolation of autoimmune T-cells G Dolton, E Zervoudi, C Rius, A Wall, HL Thomas, A Fuller, L Yeo, ... Frontiers in immunology 9, 1378, 2018 | 78 | 2018 |
Antibody stabilization of peptide–MHC multimers reveals functional T cells bearing extremely low-affinity TCRs K Tungatt, V Bianchi, MD Crowther, WE Powell, AJ Schauenburg, ... The Journal of Immunology 194 (1), 463-474, 2015 | 77 | 2015 |