Controlling the SARS-CoV-2 spike glycoprotein conformation R Henderson, RJ Edwards, K Mansouri, K Janowska, V Stalls, ... Nature structural & molecular biology 27 (10), 925-933, 2020 | 400 | 2020 |
D614G spike mutation increases SARS CoV-2 susceptibility to neutralization D Weissman, MG Alameh, T de Silva, P Collini, H Hornsby, R Brown, ... Cell host & microbe 29 (1), 23-31. e4, 2021 | 365 | 2021 |
Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity SMC Gobeil, K Janowska, S McDowell, K Mansouri, R Parks, V Stalls, ... Science 373 (6555), eabi6226, 2021 | 361 | 2021 |
D614G mutation alters SARS-CoV-2 spike conformation and enhances protease cleavage at the S1/S2 junction SMC Gobeil, K Janowska, S McDowell, K Mansouri, R Parks, K Manne, ... Cell reports 34 (2), 2021 | 274 | 2021 |
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer, SM Alam, K Wiehe, ... Cell 184 (16), 4203-4219. e32, 2021 | 248 | 2021 |
Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses KO Saunders, E Lee, R Parks, DR Martinez, D Li, H Chen, RJ Edwards, ... Nature 594 (7864), 553-559, 2021 | 228 | 2021 |
Structural diversity of the SARS-CoV-2 Omicron spike SMC Gobeil, R Henderson, V Stalls, K Janowska, X Huang, A May, ... Molecular cell 82 (11), 2050-2068. e6, 2022 | 156 | 2022 |
Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents PR Juvvadi, D Fox III, BG Bobay, MJ Hoy, SMC Gobeil, RA Venters, ... Nature Communications 10 (1), 4275, 2019 | 96 | 2019 |
A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice DR Martinez, A Schäfer, S Gobeil, D Li, G De la Cruz, R Parks, X Lu, ... Science translational medicine 14 (629), eabj7125, 2021 | 92 | 2021 |
Cryo-EM structures of SARS-CoV-2 Omicron BA. 2 spike V Stalls, J Lindenberger, SMC Gobeil, R Henderson, R Parks, M Barr, ... Cell Reports 39 (13), 2022 | 78 | 2022 |
Cold sensitivity of the SARS-CoV-2 spike ectodomain RJ Edwards, K Mansouri, V Stalls, K Manne, B Watts, R Parks, ... Nature Structural & Molecular Biology 28 (2), 128-131, 2021 | 71 | 2021 |
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies WB Williams, RR Meyerhoff, RJ Edwards, H Li, K Manne, NI Nicely, ... Cell 184 (11), 2955-2972. e25, 2021 | 70 | 2021 |
The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer, SM Alam, K Wiehe, ... BioRxiv, 2020.12. 31.424729, 2021 | 60 | 2021 |
Maintenance of native-like protein dynamics may not be required for engineering functional proteins SMC Gobeil, CM Clouthier, J Park, D Gagné, AM Berghuis, N Doucet, ... Chemistry & biology 21 (10), 1330-1340, 2014 | 38 | 2014 |
A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice DR Martinez, A Schaefer, S Gobeil, D Li, G De la Cruz, R Parks, X Lu, ... BioRxiv, 2021 | 35 | 2021 |
D614G mutation alters SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at the S1/S2 junction SMC Gobeil, K Janowska, S McDowell, K Mansouri, R Parks, K Manne, ... BioRxiv, 2020.10. 11.335299, 2020 | 22 | 2020 |
The structural dynamics of engineered β-lactamases vary broadly on three timescales yet sustain native function SMC Gobeil, MC Ebert, J Park, D Gagné, N Doucet, AM Berghuis, J Pleiss, ... Scientific Reports 9 (1), 6656, 2019 | 22 | 2019 |
Chimeric β-lactamases: global conservation of parental function and fast time-scale dynamics with increased slow motions CM Clouthier, S Morin, SMC Gobeil, N Doucet, J Blanchet, E Nguyen, ... PloS one 7 (12), e52283, 2012 | 21 | 2012 |
SARS-CoV-2 vaccination induces neutralizing antibodies against pandemic and pre-emergent SARS-related coronaviruses in monkeys KO Saunders, E Lee, R Parks, DR Martinez, D Li, H Chen, RJ Edwards, ... bioRxiv, 2021.02. 17.431492, 2021 | 15 | 2021 |
Backbone resonance assignments of an artificially engineered TEM-1/PSE-4 Class A β-lactamase chimera S Morin, CM Clouthier, S Gobeil, JN Pelletier, SM Gagné Biomolecular NMR assignments 4, 127-130, 2010 | 11 | 2010 |