Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape Z Ku, X Xie, E Davidson, X Ye, H Su, VD Menachery, Y Li, Z Yuan, ... Nature communications 12 (1), 469, 2021 | 159 | 2021 |
Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants Z Ku, X Xie, PR Hinton, X Liu, X Ye, AE Muruato, DC Ng, S Biswas, J Zou, ... Nature 595 (7869), 718-723, 2021 | 126 | 2021 |
A virus-like particle based bivalent vaccine confers dual protection against enterovirus 71 and coxsackievirus A16 infections in mice Z Ku, Q Liu, X Ye, Y Cai, X Wang, J Shi, D Li, X Jin, W An, Z Huang Vaccine 32 (34), 4296-4303, 2014 | 82 | 2014 |
Neutralizing antibodies induced by recombinant virus-like particles of enterovirus 71 genotype C4 inhibit infection at pre-and post-attachment steps Z Ku, X Ye, X Huang, Y Cai, Q Liu, Y Li, Z Su, Z Huang PLoS One 8 (2), e57601, 2013 | 79 | 2013 |
Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms X Ye, Z Ku, Q Liu, X Wang, J Shi, Y Zhang, L Kong, Y Cong, Z Huang Journal of virology 88 (1), 72-81, 2014 | 76 | 2014 |
High-yield production of recombinant virus-like particles of enterovirus 71 in Pichia pastoris and their protective efficacy against oral viral challenge in mice C Zhang, Z Ku, Q Liu, X Wang, T Chen, X Ye, D Li, X Jin, Z Huang Vaccine 33 (20), 2335-2341, 2015 | 70 | 2015 |
A virus-like particle-based tetravalent vaccine for hand, foot, and mouth disease elicits broad and balanced protective immunity W Zhang, W Dai, C Zhang, Y Zhou, P Xiong, S Wang, X Ye, Q Liu, D Zhou, ... Emerging Microbes & Infections 7 (1), 1-12, 2018 | 52 | 2018 |
Transcutaneous immunization via rapidly dissolvable microneedles protects against hand-foot-and-mouth disease caused by enterovirus 71 Z Zhu, X Ye, Z Ku, Q Liu, C Shen, H Luo, H Luan, C Zhang, S Tian, ... Journal of Controlled Release 243, 291-302, 2016 | 51 | 2016 |
A modular vaccine development platform based on sortase-mediated site-specific tagging of antigens onto virus-like particles S Tang, B Xuan, X Ye, Z Huang, Z Qian Scientific reports 6 (1), 25741, 2016 | 50 | 2016 |
Structural basis for recognition of human enterovirus 71 by a bivalent broadly neutralizing monoclonal antibody X Ye, C Fan, Z Ku, T Zuo, L Kong, C Zhang, J Shi, Q Liu, T Chen, Y Zhang, ... PLoS pathogens 12 (3), e1005454, 2016 | 48 | 2016 |
Single neutralizing monoclonal antibodies targeting the VP1 GH loop of enterovirus 71 inhibit both virus attachment and internalization during viral entry Z Ku, X Ye, J Shi, X Wang, Q Liu, Z Huang Journal of Virology 89 (23), 12084-12095, 2015 | 48 | 2015 |
A replication-defective human cytomegalovirus vaccine elicits humoral immune responses analogous to those with natural infection Y Liu, DC Freed, L Li, A Tang, F Li, EM Murray, SP Adler, MA McVoy, ... Journal of virology 93 (23), 10.1128/jvi. 00747-19, 2019 | 42 | 2019 |
A bivalent virus-like particle based vaccine induces a balanced antibody response against both enterovirus 71 and norovirus in mice X Wang, Z Ku, W Dai, T Chen, X Ye, C Zhang, Y Zhang, Q Liu, X Jin, ... Vaccine 33 (43), 5779-5785, 2015 | 35 | 2015 |
Beta-propiolactone inactivation of coxsackievirus A16 induces structural alteration and surface modification of viral capsids C Fan, X Ye, Z Ku, L Kong, Q Liu, C Xu, Y Cong, Z Huang Journal of virology 91 (8), 10.1128/jvi. 00038-17, 2017 | 33 | 2017 |
Coxsackievirus A16-like particles produced in Pichia pastoris elicit high-titer neutralizing antibodies and confer protection against lethal viral challenge in mice C Zhang, Q Liu, Z Ku, Y Hu, X Ye, Y Zhang, Z Huang Antiviral Research 129, 47-51, 2016 | 30 | 2016 |
Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses J Chen, X Ye, XY Zhang, Z Zhu, X Zhang, Z Xu, Z Ding, G Zou, Q Liu, ... Cell discovery 5 (1), 4, 2019 | 29 | 2019 |
A conditionally replication-defective cytomegalovirus vaccine elicits potent and diverse functional monoclonal antibodies in a phase I clinical trial L Li, DC Freed, Y Liu, F Li, DF Barrett, W Xiong, X Ye, SP Adler, RE Rupp, ... npj Vaccines 6 (1), 79, 2021 | 24 | 2021 |
Inactivated coxsackievirus A10 experimental vaccines protect mice against lethal viral challenge C Shen, Q Liu, Y Zhou, Z Ku, L Wang, K Lan, X Ye, Z Huang Vaccine 34 (41), 5005-5012, 2016 | 24 | 2016 |
Antibody therapies for the treatment of COVID-19 Z Ku, X Ye, GT Salazar, N Zhang, Z An Antibody Therapeutics 3 (2), 101-108, 2020 | 23 | 2020 |
Coxsackievirus A16 utilizes cell surface heparan sulfate glycosaminoglycans as its attachment receptor X Zhang, J Shi, X Ye, Z Ku, C Zhang, Q Liu, Z Huang Emerging microbes & infections 6 (1), 1-7, 2017 | 23 | 2017 |