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Sam Afkhami
Sam Afkhami
在 mcmaster.ca 的电子邮件经过验证
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引用次数
引用次数
年份
Immunological considerations for COVID-19 vaccine strategies
M Jeyanathan, S Afkhami, F Smaill, MS Miller, BD Lichty, Z Xing
Nature Reviews Immunology 20 (10), 615-632, 2020
11682020
Induction of autonomous memory alveolar macrophages requires T cell help and is critical to trained immunity
Y Yao, M Jeyanathan, S Haddadi, NG Barra, M Vaseghi-Shanjani, ...
Cell 175 (6), 1634-1650. e17, 2018
4102018
Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2
S Afkhami, MR D’Agostino, A Zhang, HD Stacey, A Marzok, A Kang, ...
Cell 185 (5), 896-915. e19, 2022
2292022
COVID‐19: Current knowledge in clinical features, immunological responses, and vaccine development
R Singh, A Kang, X Luo, M Jeyanathan, A Gillgrass, S Afkhami, Z Xing
The FASEB Journal 35 (3), 2021
1192021
Methods and clinical development of adenovirus-vectored vaccines against mucosal pathogens
S Afkhami, Y Yao, Z Xing
Molecular Therapy-Methods & Clinical Development 3, 2016
1122016
New tuberculosis vaccine strategies: taking aim at un-natural immunity
M Jeyanathan, Y Yao, S Afkhami, F Smaill, Z Xing
Trends in immunology 39 (5), 419-433, 2018
742018
Innate immune memory of tissue-resident macrophages and trained innate immunity: Re-vamping vaccine concept and strategies
Z Xing, S Afkhami, J Bavananthasivam, DK Fritz, MR D’Agostino, ...
Journal of Leucocyte Biology 108 (3), 825-834, 2020
722020
Aerosol delivery, but not intramuscular injection, of adenovirus-vectored tuberculosis vaccine induces respiratory-mucosal immunity in humans
M Jeyanathan, DK Fritz, S Afkhami, E Aguirre, KJ Howie, A Zganiacz, ...
JCI insight 7 (3), 2022
582022
Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protection
M Jeyanathan, N Thanthrige-Don, S Afkhami, R Lai, D Damjanovic, ...
Mucosal immunology 8 (6), 1373-1387, 2015
572015
CXCR3 signaling is required for restricted homing of parenteral tuberculosis vaccine–induced T cells to both the lung parenchyma and airway
M Jeyanathan, S Afkhami, A Khera, T Mandur, D Damjanovic, Y Yao, ...
The Journal of Immunology 199 (7), 2555-2569, 2017
552017
Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses
A Banerjee, N El-Sayes, P Budylowski, RA Jacob, D Richard, H Maan, ...
IScience 24 (5), 2021
492021
Mucosal immunity and novel tuberculosis vaccine strategies: route of immunisation-determined T-cell homing to restricted lung mucosal compartments
R Lai, S Afkhami, S Haddadi, M Jeyanathan, Z Xing
European Respiratory Review 24 (136), 356-360, 2015
462015
Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis
M Jeyanathan, M Vaseghi-Shanjani, S Afkhami, JA Grondin, A Kang, ...
Nature Immunology 23 (12), 1687-1702, 2022
422022
Expression and role of VLA-1 in resident memory CD8 T cell responses to respiratory mucosal viral-vectored immunization against tuberculosis
S Haddadi, N Thanthrige-Don, S Afkhami, A Khera, M Jeyanathan, Z Xing
Scientific reports 7 (1), 9525, 2017
422017
Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells
M Jeyanathan, S McCormick, R Lai, S Afkhami, CR Shaler, CN Horvath, ...
Mucosal immunology 7 (3), 670-683, 2014
412014
CD11b+ dendritic cell–mediated anti–Mycobacterium tuberculosis Th1 activation is counterregulated by CD103+ dendritic cells via IL-10
R Lai, M Jeyanathan, S Afkhami, A Zganiacz, JA Hammill, Y Yao, ...
The Journal of Immunology 200 (5), 1746-1760, 2018
402018
Mucosal-pull induction of lung-resident memory CD8 T cells in parenteral TB vaccine-primed hosts requires cognate antigens and CD4 T cells
S Haddadi, M Vaseghi-Shanjani, Y Yao, S Afkhami, MR D'Agostino, ...
Frontiers in immunology 10, 2075, 2019
372019
Spray dried human and chimpanzee adenoviral-vectored vaccines are thermally stable and immunogenic in vivo
S Afkhami, DA LeClair, S Haddadi, R Lai, SP Toniolo, HC Ertl, ...
Vaccine 35 (22), 2916-2924, 2017
372017
Excipient selection for thermally stable enveloped and non-enveloped viral vaccine platforms in dry powders
SP Toniolo, S Afkhami, A Mahmood, C Fradin, BD Lichty, MS Miller, ...
International Journal of Pharmaceutics 561, 66-73, 2019
332019
Airway macrophages mediate mucosal vaccine–induced trained innate immunity against Mycobacterium tuberculosis in early stages of infection
MR D’Agostino, R Lai, S Afkhami, A Khera, Y Yao, M Vaseghi-Shanjani, ...
The Journal of Immunology 205 (10), 2750-2762, 2020
322020
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