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Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes SL Masters, A Dunne, SL Subramanian, RL Hull, GM Tannahill, FA Sharp, ... Nature immunology 11 (10), 897-904, 2010 | 1437 | 2010 |
A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis C Sutton, C Brereton, B Keogh, KHG Mills, EC Lavelle The Journal of experimental medicine 203 (7), 1685, 2006 | 1312 | 2006 |
Autophagy controls IL-1β secretion by targeting pro-IL-1β for degradation J Harris, M Hartman, C Roche, SG Zeng, A O'Shea, FA Sharp, EM Lambe, ... Journal of Biological Chemistry 286 (11), 9587, 2011 | 909 | 2011 |
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The vaccine adjuvant chitosan promotes cellular immunity via DNA sensor cGAS-STING-dependent induction of type I interferons EC Carroll, L Jin, A Mori, N Munoz-Wolf, E Oleszycka, HBT Moran, ... Immunity 44 (3), 597-608, 2016 | 515 | 2016 |
TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells SC Higgins, AG Jarnicki, EC Lavelle, KHG Mills The Journal of Immunology 177 (11), 7980, 2006 | 494 | 2006 |
NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components SL Doyle, M Campbell, E Ozaki, RG Salomon, A Mori, PF Kenna, ... Nature medicine 18 (5), 791-798, 2012 | 466 | 2012 |
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Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation EC Lavelle, E McNeela, ME Armstrong, O Leavy, SC Higgins, KHG Mills The Journal of Immunology 171 (5), 2384, 2003 | 201 | 2003 |
Autophagy regulates IL-23 secretion and innate T cell responses through effects on IL-1 secretion C Peral de Castro, SA Jones, C Ní Cheallaigh, CA Hearnden, L Williams, ... The Journal of Immunology 189 (8), 4144-4153, 2012 | 195 | 2012 |