Optimal composition and position of histidine-containing tags improves biodistribution of 99m Tc-labeled DARPin G3 A Vorobyeva, A Schulga, E Konovalova, R Güler, J Löfblom, M Sandström, ... Scientific reports 9 (1), 1-11, 2019 | 64 | 2019 |
Comparative Evaluation of Radioiodine and Technetium-Labeled DARPin 9_29 for Radionuclide Molecular Imaging of HER2 Expression in Malignant Tumors A Vorobyeva, O Bragina, M Altai, B Mitran, A Orlova, A Shulga, ... Contrast Media & Molecular Imaging 2018, 2018 | 55 | 2018 |
Comparative evaluation of two DARPin variants: effect of affinity, size, and label on tumor targeting properties S Deyev, A Vorobyeva, A Schulga, G Proshkina, R Guler, J Lofblom, ... Molecular pharmaceutics 16 (3), 995-1008, 2019 | 50 | 2019 |
Development of a bioluminescent nitroreductase probe for preclinical imaging AG Vorobyeva, M Stanton, A Godinat, KB Lund, GG Karateev, KP Francis, ... PLoS One 10 (6), e0131037, 2015 | 50 | 2015 |
Trastuzumab cotreatment improves survival of mice with PC‐3 prostate cancer xenografts treated with the GRPR antagonist 177Lu‐DOTAGA‐PEG2‐RM26 B Mitran, SS Rinne, MW Konijnenberg, T Maina, BA Nock, M Altai, ... International journal of cancer 145 (12), 3347-3358, 2019 | 38 | 2019 |
Cyclic versus Noncyclic Chelating Scaffold for 89Zr-Labeled ZEGFR:2377 Affibody Bioconjugates Targeting Epidermal Growth Factor Receptor Overexpression D Summer, J Garousi, M Oroujeni, B Mitran, KG Andersson, A Vorobyeva, ... Molecular pharmaceutics 15 (1), 175-185, 2018 | 36 | 2018 |
Comparative evaluation of dimeric and monomeric forms of ADAPT scaffold protein for targeting of HER2-expressing tumours J Garousi, S Lindbo, J Borin, E von Witting, A Vorobyeva, M Oroujeni, ... European Journal of Pharmaceutics and Biopharmaceutics 134, 37-48, 2019 | 33 | 2019 |
Comparison of tumor‑targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2 A Vorobyeva, A Sсhulga, E Konovalova, R Güler, B Mitran, J Garousi, ... International Journal of Oncology 54 (4), 1209-1220, 2019 | 30 | 2019 |
Selection of the optimal macrocyclic chelators for labeling with 111In and 68Ga improves contrast of HER2 imaging using engineered scaffold protein ADAPT6 E von Witting, J Garousi, S Lindbo, A Vorobyeva, M Altai, M Oroujeni, ... European journal of pharmaceutics and biopharmaceutics 140, 109-120, 2019 | 29 | 2019 |
Selection of the optimal macrocyclic chelators for labeling with 111In and 68Ga improves contrast of HER2 imaging using engineered scaffold protein ADAPT6 E von Witting, J Garousi, S Lindbo, A Vorobyeva, M Altai, M Oroujeni, ... European Journal of Pharmaceutics and Biopharmaceutics 140, 109-120, 2019 | 29 | 2019 |
Effect of a radiolabel biochemical nature on tumor-targeting properties of EpCAM-binding engineered scaffold protein DARPin Ec1 SM Deyev, A Vorobyeva, A Schulga, A Abouzayed, T Günther, J Garousi, ... International Journal of Biological Macromolecules 145, 216-225, 2020 | 28 | 2020 |
Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging A Vorobyeva, A Schulga, SS Rinne, T Günther, A Orlova, S Deyev, ... International Journal of Molecular Sciences 20 (12), 3047, 2019 | 28 | 2019 |
On the prevention of kidney uptake of radiolabeled DARPins M Altai, J Garousi, SS Rinne, A Schulga, S Deyev, A Vorobyeva EJNMMI research 10 (1), 1-8, 2020 | 25 | 2020 |
Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1 A Vorobyeva, E Konovalova, T Xu, A Schulga, M Altai, J Garousi, ... International Journal of Molecular Sciences 21 (9), 3310, 2020 | 25 | 2020 |
Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of 68Ga-Labeled Tracers C Dahlsson Leitao, SS Rinne, B Mitran, A Vorobyeva, KG Andersson, ... International journal of molecular sciences 20 (5), 1080, 2019 | 25 | 2019 |
Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of 68Ga-Labeled Tracers C Dahlsson Leitao, SS Rinne, B Mitran, A Vorobyeva, KG Andersson, ... International journal of molecular sciences 20 (5), 1080, 2019 | 25 | 2019 |
Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono-and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs M Altai, C Leitao, S Rinne, A Vorobyeva, C Atterby, S Ståhl, V Tolmachev, ... Cells 7 (10), 164, 2018 | 25 | 2018 |
Comparative evaluation of tumor targeting using the anti-HER2 ADAPT scaffold protein labeled at the C-terminus with indium-111 or technetium-99m J Garousi, S Lindbo, B Mitran, J Buijs, A Vorobyeva, A Orlova, ... Scientific reports 7 (1), 1-11, 2017 | 24 | 2017 |
Site-specific conjugation of recognition tags to trastuzumab for peptide nucleic acid-mediated radionuclide HER2 pretargeting K Westerlund, A Vorobyeva, B Mitran, A Orlova, V Tolmachev, ... Biomaterials 203, 73-85, 2019 | 22 | 2019 |
Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody–DM1 Drug Conjugates H Ding, M Altai, SS Rinne, A Vorobyeva, V Tolmachev, T Gräslund, ... Cancers 11 (8), 1168, 2019 | 21 | 2019 |