Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1847* | 2020 |
Midbrain-like organoids from human pluripotent stem cells contain functional dopaminergic and neuromelanin-producing neurons J Jo, Y Xiao, AX Sun, E Cukuroglu, HD Tran, J Göke, ZY Tan, TY Saw, ... Cell stem cell 19 (2), 248-257, 2016 | 750 | 2016 |
The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity X Lu, F Sachs, LA Ramsay, PÉ Jacques, J Göke, G Bourque, HH Ng Nature structural & molecular biology 21 (4), 423-425, 2014 | 450 | 2014 |
Induction of a human pluripotent state with distinct regulatory circuitry that resembles preimplantation epiblast YS Chan*, J Göke*, JH Ng*, X Lu, KAU Gonzales, CP Tan, WQ Tng, ... Cell stem cell 13 (6), 663-675, 2013 | 447 | 2013 |
Dynamic transcription of distinct classes of endogenous retroviral elements marks specific populations of early human embryonic cells J Göke, X Lu, YS Chan, HH Ng, LH Ly, F Sachs, I Szczerbinska Cell stem cell 16 (2), 135-141, 2015 | 359 | 2015 |
X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes H Hu, SA Haas, J Chelly, H Van Esch, M Raynaud, APM de Brouwer, ... Molecular psychiatry 21 (1), 133-148, 2016 | 311 | 2016 |
Genomic basis for RNA alterations in cancer PCAWG Transcriptome Core Group Calabrese Claudia 2 Davidson Natalie R. 3 4 5 ... Nature 578 (7793), 129-136, 2020 | 310 | 2020 |
Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog V Karwacki-Neisius, J Göke, R Osorno, F Halbritter, JH Ng, AY Weiße, ... Cell stem cell 12 (5), 531-545, 2013 | 214 | 2013 |
Identification of differential RNA modifications from nanopore direct RNA sequencing with xPore PN Pratanwanich, F Yao, Y Chen, CWQ Koh, YK Wan, C Hendra, P Poon, ... Nature biotechnology 39 (11), 1394-1402, 2021 | 205 | 2021 |
Localized Plasticity in the Streamlined Genomes of Vinyl Chloride Respiring Dehalococcoides PJ McMurdie, SF Behrens, JA Müller, J Göke, KM Ritalahti, R Wagner, ... PLoS Genetics 5 (11), e1000714, 2009 | 191 | 2009 |
A pan-cancer transcriptome analysis reveals pervasive regulation through alternative promoters D Demircioğlu, E Cukuroglu, M Kindermans, T Nandi, C Calabrese, ... Cell 178 (6), 1465-1477. e17, 2019 | 179 | 2019 |
Reproducible, scalable, and shareable analysis pipelines with bioinformatics workflow managers L Wratten, A Wilm, J Göke Nature methods 18 (10), 1161-1168, 2021 | 161 | 2021 |
Klf2 is an essential factor that sustains ground state pluripotency JC Yeo, J Jiang, ZY Tan, GR Yim, JH Ng, J Göke, P Kraus, H Liang, ... Cell stem cell 14 (6), 864-872, 2014 | 144 | 2014 |
Detection of m6A from direct RNA sequencing using a multiple instance learning framework C Hendra, PN Pratanwanich, YK Wan, WSS Goh, A Thiery, J Göke Nature methods 19 (12), 1590-1598, 2022 | 127 | 2022 |
Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma A Lechner, HA Schlößer, M Thelen, K Wennhold, SI Rothschild, R Gilles, ... Oncoimmunology 8 (3), 1535293, 2019 | 125 | 2019 |
Genome-wide kinase-chromatin interactions reveal the regulatory network of ERK signaling in human embryonic stem cells J Göke, YS Chan, J Yan, M Vingron, HH Ng Molecular cell 50 (6), 844-855, 2013 | 110 | 2013 |
SON connects the splicing-regulatory network with pluripotency in human embryonic stem cells X Lu*, J Göke*, F Sachs, PÉ Jacques, H Liang, B Feng, G Bourque, ... Nature cell biology 15 (10), 1141, 2013 | 107 | 2013 |
Molecular features underlying neurodegeneration identified through in vitro modeling of genetically diverse Parkinson’s disease patients L Lin, J Göke, E Cukuroglu, MR Dranias, AMJ VanDongen, LW Stanton Cell reports 15 (11), 2411-2426, 2016 | 103 | 2016 |
Zscan4c activates endogenous retrovirus MERVL and cleavage embryo genes W Zhang, F Chen, R Chen, D Xie, J Yang, X Zhao, R Guo, Y Zhang, ... Nucleic acids research 47 (16), 8485-8501, 2019 | 90 | 2019 |
CTRL+ INSERT: retrotransposons and their contribution to regulation and innovation of the transcriptome J Göke, HH Ng EMBO reports 17 (8), 1131-1144, 2016 | 89 | 2016 |