Synthesis and in Vitro Cannabinoid Receptor 1 Activity of Recently Detected Synthetic Cannabinoids 4F-MDMB-BICA, 5F-MPP-PICA, MMB-4en-PICA, CUMYL … A Cannaert, E Sparkes, E Pike, JL Luo, A Fang, RC Kevin, R Ellison, ... ACS Chemical Neuroscience 11 (24), 4434-4446, 2020 | 91 | 2020 |
Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB‐4en‐PICA, MDMB‐4en‐PINACA, ADB‐4en‐PINACA and MMB‐4CN‐BUTINACA using … KE Grafinger, A Cannaert, A Ametovski, E Sparkes, E Cairns, SD Banister, ... Drug Testing and Analysis, 2021 | 39 | 2021 |
Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB‐4en‐PICA, MDMB‐4en‐PINACA, ADB‐4en‐PINACA, and MMB‐4CN‐BUTINACA using … E Pike, KE Grafinger, A Cannaert, A Ametovski, JL Luo, E Sparkes, ... Drug testing and analysis 13 (7), 1383-1401, 2021 | 26 | 2021 |
Structure–activity relationships of valine, tert-leucine, and phenylalanine amino acid-derived synthetic cannabinoid receptor agonists related to ADB-BUTINACA, APP-BUTINACA … E Sparkes, EA Cairns, RC Kevin, F Lai, KE Grafinger, S Chen, ... RSC Medicinal Chemistry 13 (2), 156-174, 2022 | 20 | 2022 |
Exploring Stereochemical and Conformational Requirements at Cannabinoid Receptors for Synthetic Cannabinoids Related to SDB-006, 5F-SDB-006, CUMYL-PICA, and 5F-CUMYL-PICA A Ametovski, C Macdonald, JJ Manning, SAS Haneef, M Santiago, ... ACS Chemical Neuroscience 11 (21), 3672-3682, 2020 | 18 | 2020 |
Defining Steric Requirements at CB1 and CB2 Cannabinoid Receptors Using Synthetic Cannabinoid Receptor Agonists 5F-AB-PINACA, 5F-ADB-PINACA, PX-1 … J Markham, E Sparkes, R Boyd, S Chen, JJ Manning, D Finlay, F Lai, ... ACS Chemical Neuroscience 13 (8), 1281-1295, 2022 | 10 | 2022 |
Characterisation of AMB-FUBINACA metabolism and CB1-mediated activity of its acid metabolite HDJ Webb, DB Finlay, S Chen, AJ Vernall, E Sparkes, SD Banister, ... Forensic Toxicology 41 (1), 114-125, 2023 | 5 | 2023 |
Comprehensive Characterization of a Systematic Library of Alkyl and Alicyclic Synthetic Cannabinoids Related to CUMYL-PICA, CUMYL-BUTICA, CUMYL-CBMICA, and CUMYL-PINACA LK Janssens, A Ametovski, E Sparkes, R Boyd, F Lai, CJ Maloney, ... ACS Chemical Neuroscience 14 (1), 35-52, 2022 | 4 | 2022 |
Synthesis and pharmacological evaluation of newly detected synthetic cannabinoid receptor agonists AB-4CN-BUTICA, MMB-4CN-BUTINACA, MDMB-4F-BUTICA, MDMB-4F-BUTINACA and their … E Sparkes, R Boyd, S Chen, JW Markham, JL Luo, T Foyzun, H Zaman, ... Frontiers in Psychiatry, 2022 | 3 | 2022 |
Investigating selectivity and bias for G protein subtypes and β-arrestins by synthetic cannabinoid receptor agonists at the cannabinoid CB1 receptor B Ryalls, M Patel, E Sparkes, SD Banister, DB Finlay, M Glass Biochemical Pharmacology 222, 116052, 2024 | 2 | 2024 |
Structure–Activity Relationships, Deuteration, and Fluorination of Synthetic Cannabinoid Receptor Agonists Related to AKB48, 5F-AKB-48, and AFUBIATA E Sparkes, CJ Maloney, JW Markham, C Dane, R Boyd, J Gilchrist, M Moir, ... ACS Chemical Neuroscience, 2024 | | 2024 |
Synthesis and Functional Evaluation of Synthetic Cannabinoid Receptor Agonists Related to ADB-HEXINACA E Sparkes, A Timmerman, JW Markham, R Boyd, R Gordon, KA Walker, ... ACS Chemical Neuroscience 15 (9), 1787-1812, 2024 | | 2024 |
Exploring structure-activity relationships of synthetic cannabinoid receptor agonists EJ Sparkes | | 2024 |
Synthesis and functional evaluation of proteinogenic amino acid-derived synthetic cannabinoid receptor agonists related to MPP-5F-PICA, MMB-5F-PICA, and MDMB-5F-PICA E Sparkes, J Markham, R Boyd, M Udoh, R Gordon, H Zaman, K Walker, ... RSC Medicinal Chemistry, 2024 | | 2024 |