| Metabolic modulation of glioblastoma with dichloroacetate ED Michelakis, G Sutendra, P Dromparis, L Webster, A Haromy, E Niven, ... Science translational medicine 2 (31), 31ra34-31ra34, 2010 | 886 | 2010 |
| A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation G Sutendra, A Kinnaird, P Dromparis, R Paulin, TH Stenson, A Haromy, ... Cell 158 (1), 84-97, 2014 | 548 | 2014 |
| Mitochondria in vascular health and disease P Dromparis, ED Michelakis Annual review of physiology 75, 95-126, 2013 | 251 | 2013 |
| The role of Nogo and the mitochondria–endoplasmic reticulum unit in pulmonary hypertension G Sutendra, P Dromparis, P Wright, S Bonnet, A Haromy, Z Hao, ... Science translational medicine 3 (88), 88ra55-88ra55, 2011 | 239 | 2011 |
| A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary … G Sutendra, P Dromparis, R Paulin, S Zervopoulos, A Haromy, ... Journal of molecular medicine 91, 1315-1327, 2013 | 233 | 2013 |
| Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer G Sutendra, P Dromparis, A Kinnaird, TH Stenson, A Haromy, JMR Parker, ... Oncogene 32 (13), 1638-1650, 2013 | 230 | 2013 |
| Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans R Paulin, P Dromparis, G Sutendra, V Gurtu, S Zervopoulos, L Bowers, ... Cell metabolism 20 (5), 827-839, 2014 | 222 | 2014 |
| Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension P Dromparis, R Paulin, TH Stenson, A Haromy, G Sutendra, ... Circulation 127 (1), 115-125, 2013 | 173 | 2013 |
| Dehydroepiandrosterone reverses systemic vascular remodeling through the inhibition of the Akt/GSK3-β/NFAT axis S Bonnet, R Paulin, G Sutendra, P Dromparis, M Roy, KO Watson, ... Circulation 120 (13), 1231-1240, 2009 | 152 | 2009 |
| A miR-208–Mef2 axis drives the decompensation of right ventricular function in pulmonary hypertension R Paulin, G Sutendra, V Gurtu, P Dromparis, A Haromy, S Provencher, ... Circulation research 116 (1), 56-69, 2015 | 135 | 2015 |
| Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodeling and … P Dromparis, R Paulin, G Sutendra, AC Qi, S Bonnet, ED Michelakis Circulation research 113 (2), 126-136, 2013 | 135 | 2013 |
| Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension G Sutendra, P Dromparis, S Bonnet, A Haromy, MS McMurtry, ... Journal of molecular medicine 89, 771-783, 2011 | 127 | 2011 |
| The role of mitochondria in pulmonary vascular remodeling P Dromparis, G Sutendra, ED Michelakis Journal of molecular medicine 88, 1003-1010, 2010 | 122 | 2010 |
| Metabolic modulation of clear-cell renal cell carcinoma with dichloroacetate, an inhibitor of pyruvate dehydrogenase kinase A Kinnaird, P Dromparis, B Saleme, V Gurtu, K Watson, R Paulin, ... European urology 69 (4), 734-744, 2016 | 77 | 2016 |
| Negative pressure ventilation decreases inflammation and lung edema during normothermic ex-vivo lung perfusion NS Aboelnazar, S Himmat, S Hatami, CW White, MS Burhani, ... The Journal of Heart and Lung Transplantation 37 (4), 520-530, 2018 | 59 | 2018 |
| Ex vivo perfusion induces a time-and perfusate-dependent molecular repair response in explanted porcine lungs P Dromparis, NS Aboelnazar, S Wagner, S Himmat, CW White, S Hatami, ... American Journal of Transplantation 19 (4), 1024-1036, 2019 | 23 | 2019 |
| Pioglitazone inhibits HIF-1α-dependent angiogenesis in rats by paracrine and direct effects on endothelial cells P Dromparis, G Sutendra, R Paulin, S Proctor, ED Michelakis, ... Journal of Molecular Medicine 92, 497-507, 2014 | 20 | 2014 |
| Continuous hemodialysis does not improve graft function during ex vivo lung perfusion over 24 hours MT Buchko, S Himmat, CJ Stewart, S Hatami, P Dromparis, BA Adam, ... Transplantation proceedings 51 (6), 2022-2028, 2019 | 14 | 2019 |
| A decrease in hypoxic pulmonary vasoconstriction correlates with increased inflammation during extended normothermic ex vivo lung perfusion S Himmat, A Alzamil, N Aboelnazar, S Hatami, C White, P Dromparis, ... Artificial organs 42 (3), 271-279, 2018 | 13 | 2018 |
| F2-isoprostanes: an emerging pulmonary arterial hypertension biomarker and potential link to the metabolic theory of pulmonary arterial hypertension? P Dromparis, ED Michelakis Chest 142 (4), 816-820, 2012 | 10 | 2012 |
