The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase T Gerken, CA Girard, YCL Tung, CJ Webby, V Saudek, KS Hewitson, ... Science 318 (5855), 1469-1472, 2007 | 1799 | 2007 |
Role for the obesity-related FTO gene in the cellular sensing of amino acids P Gulati, MK Cheung, R Antrobus, CD Church, HP Harding, YCL Tung, ... Proceedings of the National Academy of Sciences 110 (7), 2557-2562, 2013 | 199 | 2013 |
Prevalence of Loss-of-Function FTO Mutations in Lean and Obese Individuals D Meyre, K Proulx, H Kawagoe-Takaki, V Vatin, R Gutiérrez-Aguilar, ... Diabetes 59 (1), 311-318, 2010 | 132 | 2010 |
Novel leptin-regulated genes revealed by transcriptional profiling of the hypothalamic paraventricular nucleus YCL Tung, M Ma, S Piper, A Coll, S O'Rahilly, GSH Yeo Journal of Neuroscience 28 (47), 12419-12426, 2008 | 125 | 2008 |
Comparison of human and murine enteroendocrine cells by transcriptomic and peptidomic profiling GP Roberts, P Larraufie, P Richards, RG Kay, SG Galvin, ... Diabetes 68 (5), 1062-1072, 2019 | 111 | 2019 |
Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome J Polex-Wolf, BYH Lam, R Larder, J Tadross, D Rimmington, F Bosch, ... The Journal of clinical investigation 128 (3), 960-969, 2018 | 95 | 2018 |
Human embryonic genome activation initiates at the one-cell stage M Asami, BYH Lam, MK Ma, K Rainbow, S Braun, MD VerMilyea, ... Cell Stem Cell 29 (2), 209-216. e4, 2022 | 88 | 2022 |
Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm P Gulati, E Avezov, M Ma, R Antrobus, P Lehner, S O’Rahilly, GSH Yeo Bioscience reports 34 (5), e00144, 2014 | 87 | 2014 |
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells M Yang, T Darwish, P Larraufie, D Rimmington, I Cimino, DA Goldspink, ... Scientific Reports 11 (1), 2529, 2021 | 64 | 2021 |
SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation G Bidault, S Virtue, K Petkevicius, HE Jolin, A Dugourd, AC Guénantin, ... Nature metabolism 3 (9), 1150-1162, 2021 | 40 | 2021 |
FTO is necessary for the induction of leptin resistance by high-fat feeding YCL Tung, P Gulati, CH Liu, D Rimmington, R Dennis, M Ma, V Saudek, ... Molecular metabolism 4 (4), 287-298, 2015 | 39 | 2015 |
A coding variant in FTO confers susceptibility to thiopurine-induced leukopenia in East Asian patients with IBD HS Kim, JH Cheon, ES Jung, J Park, S Aum, SJ Park, S Eun, J Lee, ... Gut 66 (11), 1926-1935, 2017 | 38 | 2017 |
Contributions of function-altering variants in genes implicated in pubertal timing and body mass for self-limited delayed puberty SR Howard, L Guasti, A Poliandri, A David, CP Cabrera, MR Barnes, ... The Journal of Clinical Endocrinology & Metabolism 103 (2), 649-659, 2018 | 35 | 2018 |
Innate lymphoid cells promote recovery of ventricular function after myocardial infarction X Yu, SA Newland, TX Zhao, Y Lu, AS Sage, Y Sun, RS Sriranjan, ... Journal of the American College of Cardiology 78 (11), 1127-1142, 2021 | 33 | 2021 |
Impaired Autophagy in CD11b+ Dendritic Cells Expands CD4+ Regulatory T Cells and Limits Atherosclerosis in Mice M Clement, J Raffort, F Lareyre, D Tsiantoulas, S Newland, Y Lu, ... Circulation Research 125 (11), 1019-1034, 2019 | 33 | 2019 |
Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate M Ma, HP Harding, S O'rahilly, D Ron, GSH Yeo Biochemical Journal 444 (2), 183-187, 2012 | 33 | 2012 |
Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function CM Hammerle, I Sandovici, GV Brierley, NM Smith, WE Zimmer, ... PLoS Genetics 16 (10), e1009069, 2020 | 17 | 2020 |
Adult-onset hyperinsulinaemic hypoglycaemia in clinical practice: diagnosis, aetiology and management BG Challis, AS Powlson, RT Casey, C Pearson, BY Lam, M Ma, D Pitfield, ... Endocrine connections 6 (7), 540-548, 2017 | 14 | 2017 |
Combination of ginsenosides Rb2 and Rg3 promotes angiogenic phenotype of human endothelial cells via PI3K/akt and MAPK/ERK pathways RJ Choi, SZ Mohamad Zobir, B Alexander-Dann, N Sharma, MKL Ma, ... Frontiers in Pharmacology 12, 618773, 2021 | 13 | 2021 |
Behavioural and neurochemical mechanisms underpinning the feeding-suppressive effect of GLP-1/CCK combinatorial therapy E Roth, S Benoit, B Quentin, B Lam, S Will, M Ma, N Heeley, T Darwish, ... Molecular Metabolism 43, 101118, 2021 | 13 | 2021 |