| The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo KL Meerbrey, G Hu, JD Kessler, K Roarty, MZ Li, JE Fang, JI Herschkowitz, ... Proceedings of the National Academy of Sciences 108 (9), 3665-3670, 2011 | 715 | 2011 |
| TGF-β promotes Th17 cell development through inhibition of SOCS3 H Qin, L Wang, T Feng, CO Elson, SA Niyongere, SJ Lee, SL Reynolds, ... The Journal of Immunology 183 (1), 97-105, 2009 | 313 | 2009 |
| Wnt5a is required for proper mammary gland development and TGF-β-mediated inhibition of ductal growth K Roarty, R Serra Oxford University Press for The Company of Biologists Limited 134 (21), 3929 …, 2007 | 208 | 2007 |
| Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression EC Brantley, LB Nabors, GY Gillespie, YH Choi, CA Palmer, K Harrison, ... Clinical cancer research 14 (15), 4694-4704, 2008 | 206 | 2008 |
| STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer W Wei, DJ Tweardy, M Zhang, X Zhang, J Landua, I Petrovic, W Bu, ... Stem cells 32 (10), 2571-2582, 2014 | 128 | 2014 |
| Fibroblast growth factor receptor signaling is essential for normal mammary gland development and stem cell function AC Pond, X Bin, T Batts, K Roarty, S Hilsenbeck, JM Rosen Stem cells 31 (1), 178-189, 2013 | 104 | 2013 |
| Wnt and mammary stem cells: hormones cannot fly wingless K Roarty, JM Rosen Current opinion in pharmacology 10 (6), 643-649, 2010 | 101 | 2010 |
| Loss of TGF-β or Wnt5a results in an increase in Wnt/β-catenin activity and redirects mammary tumour phenotype K Roarty, SE Baxley, MR Crowley, AR Frost, R Serra Breast Cancer Research 11, 1-11, 2009 | 88 | 2009 |
| The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes A Sreekumar, K Roarty, JM Rosen Endocrine-related cancer 22 (6), T161, 2015 | 77 | 2015 |
| Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium K Roarty, AN Shore, CJ Creighton, JM Rosen Journal of Cell Biology 208 (3), 351-366, 2015 | 62 | 2015 |
| Pregnancy-Induced Noncoding RNA (PINC) Associates with Polycomb Repressive Complex 2 and Regulates Mammary Epithelial Differentiation AN Shore, EB Kabotyanski, K Roarty, MA Smith, Y Zhang, CJ Creighton, ... PLoS Genetics 8 (7), e1002840, 2012 | 62 | 2012 |
| WNT-mediated regulation of FOXO1 constitutes a critical axis maintaining pubertal mammary stem cell homeostasis A Sreekumar, MJ Toneff, E Toh, K Roarty, CJ Creighton, GK Belka, ... Developmental cell 43 (4), 436-448. e6, 2017 | 42 | 2017 |
| Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition N Zhao, RT Powell, X Yuan, G Bae, KP Roarty, F Stossi, M Strempfl, ... Nature communications 12 (1), 4262, 2021 | 41 | 2021 |
| Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression K Roarty, AD Pfefferle, CJ Creighton, CM Perou, JM Rosen Oncogene 36 (43), 5958-5968, 2017 | 40 | 2017 |
| Laboratory models for investigating breast cancer therapy resistance and metastasis K Roarty, GV Echeverria Frontiers in oncology 11, 645698, 2021 | 38 | 2021 |
| Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity? JM Rosen, K Roarty Breast Cancer Research 16, 1-6, 2014 | 31 | 2014 |
| Role for primary cilia in the regulation of mouse ovarian function ET Johnson, T Nicola, K Roarty, BK Yoder, CJ Haycraft, R Serra Developmental Dynamics: An Official Publication of the American Association …, 2008 | 31 | 2008 |
| FGFR1-activated translation of WNT pathway components with structured 5′ UTRs is vulnerable to inhibition of EIF4A-dependent translation initiation TM Nguyen, EB Kabotyanski, Y Dou, LC Reineke, P Zhang, XHF Zhang, ... Cancer research 78 (15), 4229-4240, 2018 | 25 | 2018 |
| Noncanonical Wnt/Ror2 signaling regulates cell–matrix adhesion to prompt directional tumor cell invasion in breast cancer H Si, N Zhao, A Pedroza, AM Zaske, JM Rosen, CJ Creighton, K Roarty Molecular Biology of the Cell 33 (11), ar103, 2022 | 4 | 2022 |
| Pygopus 2: tilting the Wnt-Notch balance in mammary epithelial lineage determination K Roarty, JM Rosen Breast Cancer Research 15, 1-3, 2013 | 4 | 2013 |
