| On the evolution of structure in aminoacyl-tRNA synthetases P O'Donoghue, Z Luthey-Schulten Microbiol. Mol. Biol. Rev. 67 (4), 550-573, 2003 | 329 | 2003 |
| UGA is an additional glycine codon in uncultured SR1 bacteria from the human microbiota JH Campbell, P O’Donoghue, AG Campbell, P Schwientek, A Sczyrba, ... Proceedings of the National Academy of Sciences 110 (14), 5540-5545, 2013 | 300 | 2013 |
| Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation JM Kavran, S Gundllapalli, P O'Donoghue, M Englert, D Söll, TA Steitz Proceedings of the National Academy of Sciences 104 (27), 11268-11273, 2007 | 269 | 2007 |
| RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea J Yuan, S Palioura, JC Salazar, D Su, P O'Donoghue, MJ Hohn, ... Proceedings of the National Academy of Sciences 103 (50), 18923-18927, 2006 | 241 | 2006 |
| Pyrrolysyl-tRNA synthetase–tRNAPyl structure reveals the molecular basis of orthogonality K Nozawa, P O’Donoghue, S Gundllapalli, Y Araiso, R Ishitani, ... Nature 457 (7233), 1163-1167, 2009 | 211 | 2009 |
| Upgrading protein synthesis for synthetic biology P O'donoghue, J Ling, YS Wang, D Söll Nature chemical biology 9 (10), 594-598, 2013 | 181 | 2013 |
| Genetic code flexibility in microorganisms: novel mechanisms and impact on physiology J Ling, P O'donoghue, D Söll Nature Reviews Microbiology 13 (11), 707-721, 2015 | 131 | 2015 |
| Genetic code flexibility in microorganisms: novel mechanisms and impact on physiology J Ling, P O'donoghue, D Söll Nature Reviews Microbiology 13 (11), 707-721, 2015 | 131 | 2015 |
| Polyspecific pyrrolysyl-tRNA synthetases from directed evolution LT Guo, YS Wang, A Nakamura, D Eiler, JM Kavran, M Wong, ... Proceedings of the National Academy of Sciences 111 (47), 16724-16729, 2014 | 128 | 2014 |
| Recoding the Genetic Code with Selenocysteine MJ Bröcker, JML Ho, GM Church, D Söll, P O'Donoghue Angewandte Chemie International Edition 53 (1), 319-323, 2014 | 101 | 2014 |
| The evolutionary history of Cys-tRNACys formation P O'Donoghue, A Sethi, CR Woese, ZA Luthey-Schulten Proceedings of the National Academy of Sciences 102 (52), 19003-19008, 2005 | 101 | 2005 |
| The evolutionary history of Cys-tRNACys formation P O'Donoghue, A Sethi, CR Woese, ZA Luthey-Schulten Proceedings of the National Academy of Sciences 102 (52), 19003-19008, 2005 | 101 | 2005 |
| Near-cognate suppression of amber, opal and quadruplet codons competes with aminoacyl-tRNA Pyl for genetic code expansion P O’Donoghue, L Prat, IU Heinemann, J Ling, K Odoi, WR Liu, D Söll FEBS letters 586 (21), 3931-3937, 2012 | 95 | 2012 |
| Revealing the amino acid composition of proteins within an expanded genetic code HR Aerni, MA Shifman, S Rogulina, P O'Donoghue, J Rinehart Nucleic acids research 43 (2), e8-e8, 2015 | 93 | 2015 |
| Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems J Yuan, P O’Donoghue, A Ambrogelly, S Gundllapalli, RL Sherrer, ... FEBS letters 584 (2), 342-349, 2010 | 88 | 2010 |
| Evolutionary profiles derived from the QR factorization of multiple structural alignments gives an economy of information P O'Donoghue, Z Luthey-Schulten Journal of molecular biology 346 (3), 875-894, 2005 | 78 | 2005 |
| Pathways to disease from natural variations in human cytoplasmic tRNAs JT Lant, MD Berg, IU Heinemann, CJ Brandl, P O'Donoghue Journal of Biological Chemistry 294 (14), 5294-5308, 2019 | 74 | 2019 |
| The amino-terminal domain of pyrrolysyl-tRNA synthetase is dispensable in vitro but required for in vivo activity S Herring, A Ambrogelly, S Gundllapalli, P O’Donoghue, CR Polycarpo, ... FEBS letters 581 (17), 3197-3203, 2007 | 68 | 2007 |
| Emergence of the universal genetic code imprinted in an RNA record MJ Hohn, HS Park, P O'Donoghue, M Schnitzbauer, D Söll Proceedings of the National Academy of Sciences 103 (48), 18095-18100, 2006 | 67 | 2006 |
| Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation Y Araiso, S Palioura, R Ishitani, RL Sherrer, P O’Donoghue, J Yuan, ... Nucleic acids research 36 (4), 1187-1199, 2008 | 65 | 2008 |
