| Adeno-associated virus-based gene therapy for CNS diseases M Hocquemiller, L Giersch, M Audrain, S Parker, N Cartier Human gene therapy 27 (7), 478-496, 2016 | 316 | 2016 |
| Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer’s disease mouse model R Fol, J Braudeau, S Ludewig, T Abel, SW Weyer, JP Roederer, F Brod, ... Acta neuropathologica 131, 247-266, 2016 | 188 | 2016 |
| Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer’s disease mice S Alves, G Churlaud, M Audrain, K Michaelsen-Preusse, R Fol, B Souchet, ... Brain 140 (3), 826-842, 2017 | 162 | 2017 |
| Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology MA Burlot, J Braudeau, K Michaelsen-Preusse, B Potier, S Ayciriex, ... Human molecular genetics 24 (21), 5965-5976, 2015 | 126 | 2015 |
| Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease ND Beckmann, WJ Lin, M Wang, AT Cohain, AW Charney, P Wang, W Ma, ... Nature communications 11 (1), 3942, 2020 | 114 | 2020 |
| Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer’s pathology JV Haure-Mirande, M Audrain, T Fanutza, SH Kim, WL Klein, C Glabe, ... Acta neuropathologica 134, 769-788, 2017 | 108 | 2017 |
| VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice F El Gaamouch, M Audrain, WJ Lin, N Beckmann, C Jiang, S Hariharan, ... Molecular neurodegeneration 15, 1-19, 2020 | 70 | 2020 |
| Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular … JV Haure-Mirande, M Wang, M Audrain, T Fanutza, SH Kim, S Heja, ... Molecular psychiatry 24 (3), 431-446, 2019 | 70 | 2019 |
| Microglial TYROBP/DAP12 in Alzheimer’s disease: Transduction of physiological and pathological signals across TREM2 JV Haure-Mirande, M Audrain, ME Ehrlich, S Gandy Molecular Neurodegeneration 17 (1), 55, 2022 | 59 | 2022 |
| Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and … M Audrain, JV Haure-Mirande, M Wang, SH Kim, T Fanutza, ... Molecular psychiatry 24 (9), 1383-1397, 2019 | 53 | 2019 |
| Alzheimer’s disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression M Audrain, R Fol, P Dutar, B Potier, JM Billard, J Flament, S Alves, ... Molecular neurodegeneration 11, 1-17, 2016 | 46 | 2016 |
| Reactive or transgenic increase in microglial TYROBP reveals a TREM2‐independent TYROBP–APOE link in wild‐type and Alzheimer's‐related mice M Audrain, JV Haure‐Mirande, J Mleczko, M Wang, JK Griffin, ... Alzheimer's & Dementia 17 (2), 149-163, 2021 | 44 | 2021 |
| Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice B Souchet, M Audrain, JM Billard, J Dairou, R Fol, NS Orefice, S Tada, ... Acta neuropathologica communications 7, 1-15, 2019 | 40 | 2019 |
| miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease B Readhead, JV Haure-Mirande, D Mastroeni, M Audrain, T Fanutza, ... Acta neuropathologica 140, 295-315, 2020 | 33 | 2020 |
| βAPP processing drives gradual tau pathology in an age-dependent amyloid rat model of Alzheimer’s disease M Audrain, B Souchet, S Alves, R Fol, A Viode, A Haddjeri, S Tada, ... Cerebral Cortex 28 (11), 3976-3993, 2018 | 22 | 2018 |
| Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD T Afroz, E Chevalier, M Audrain, C Dumayne, T Ziehm, R Moser, ... Neurobiology of Disease 179, 106050, 2023 | 11 | 2023 |
| Multiscale causal network models of Alzheimer’s disease identify VGF as a key regulator of disease ND Beckmann, WJ Lin, M Wang, AT Cohain, P Wang, W Ma, YC Wang, ... bioRxiv, 458430, 2018 | 9 | 2018 |
| Effect of Aging and a Dual Orexin Receptor Antagonist on Sleep Architecture and Non-REM Oscillations Including an REM Behavior Disorder Phenotype in the PS19 Mouse Model of … K Kam, K Vetter, RA Tejiram, WD Pettibone, K Shim, M Audrain, L Yu, ... Journal of Neuroscience 43 (25), 4738-4749, 2023 | 7 | 2023 |
| Cerebral phospho-tau acts synergistically with soluble Aβ42 leading to mild cognitive impairment in AAV-AD rats B Souchet, M Audrain, Y Gu, MF Lindberg, NS Orefice, E Rey, N Cartier, ... The Journal of Prevention of Alzheimer's Disease 9 (3), 480-490, 2022 | 7 | 2022 |
| Is it time to rethink the Alzheimer's disease drug development strategy by targeting its silent phase? B Souchet, M Audrain, B Billoir, L Lecanu, S Tada, J Braudeau Neural regeneration research 13 (2), 224-225, 2018 | 7 | 2018 |
