Tracking the evolution of non–small-cell lung cancer M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ... New England Journal of Medicine 376 (22), 2109-2121, 2017 | 2225 | 2017 |
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ... Nature 545 (7655), 446-451, 2017 | 1711 | 2017 |
Pan-cancer analysis of whole genomes I The, TPCA of Whole, Genomes Consortium Nature 578 (7793), 82, 2020 | 1601 | 2020 |
Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal S Turajlic, H Xu, K Litchfield, A Rowan, S Horswell, T Chambers, ... Cell 173 (3), 595-610. e11, 2018 | 559 | 2018 |
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ... Nature Medicine, 1-14, 2021 | 555* | 2021 |
Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling Y Yuan, H Failmezger, OM Rueda, HR Ali, S Gräf, SF Chin, RF Schwarz, ... Science translational medicine 4 (157), 157ra143-157ra143, 2012 | 466 | 2012 |
Cancer evolution: mathematical models and computational inference N Beerenwinkel, RF Schwarz, M Gerstung, F Markowetz Systematic biology 64 (1), e1-e25, 2015 | 409 | 2015 |
Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis RF Schwarz, CKY Ng, SL Cooke, S Newman, J Temple, AM Piskorz, ... PLoS Med 12 (2), e1001789, 2015 | 402 | 2015 |
The ITS2 Database III—sequences and structures for phylogeny C Koetschan, F Förster, A Keller, T Schleicher, B Ruderisch, R Schwarz, ... Nucleic acids research 38 (suppl 1), D275-D279, 2010 | 314 | 2010 |
Genomic basis for RNA alterations in cancer PCAWG Transcriptome Core Group Calabrese Claudia 2 Davidson Natalie R. 3 4 5 ... Nature 578 (7793), 129-136, 2020 | 304 | 2020 |
Pervasive chromosomal instability and karyotype order in tumour evolution TBK Watkins, EL Lim, M Petkovic, S Elizalde, NJ Birkbak, GA Wilson, ... Nature 587 (7832), 126-132, 2020 | 291 | 2020 |
Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma RP Koche, E Rodriguez-Fos, K Helmsauer, M Burkert, IC MacArthur, ... Nature Genetics, 1-6, 2019 | 248 | 2019 |
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution S López, EL Lim, S Horswell, K Haase, A Huebner, M Dietzen, ... Nature Genetics 52 (3), 283-293, 2020 | 206 | 2020 |
Diverse epigenetic strategies interact to control epidermal differentiation KW Mulder, X Wang, C Escriu, Y Ito, RF Schwarz, J Gillis, G Sirokmany, ... Nature cell biology 14 (7), 753-763, 2012 | 170 | 2012 |
Phylogenetic quantification of intra-tumour heterogeneity RF Schwarz, A Trinh, B Sipos, JD Brenton, N Goldman, F Markowetz PLoS computational biology 10 (4), e1003535, 2014 | 168 | 2014 |
13C isotopologue perturbation studies of Listeria monocytogenes carbon metabolism and its modulation by the virulence regulator PrfA W Eisenreich, J Slaghuis, R Laupitz, J Bussemer, J Stritzker, C Schwarz, ... Proceedings of the National Academy of Sciences 103 (7), 2040-2045, 2006 | 110 | 2006 |
YANA–a software tool for analyzing flux modes, gene-expression and enzyme activities R Schwarz, P Musch, A von Kamp, B Engels, H Schirmer, S Schuster, ... BMC bioinformatics 6, 1-12, 2005 | 102 | 2005 |
The evolution of lung cancer and impact of subclonal selection in TRACERx AM Frankell, M Dietzen, M Al Bakir, EL Lim, T Karasaki, S Ward, ... Nature 616 (7957), 525-533, 2023 | 97 | 2023 |
Integrated network reconstruction, visualization and analysis using YANAsquare R Schwarz, C Liang, C Kaleta, M Kühnel, E Hoffmann, S Kuznetsov, ... BMC bioinformatics 8, 1-10, 2007 | 96 | 2007 |
The metabolic background is a global player in Saccharomyces gene expression epistasis MT Alam, A Zelezniak, M Mülleder, P Shliaha, R Schwarz, F Capuano, ... Nature microbiology 1 (3), 1-10, 2016 | 93 | 2016 |