关注
Sarah S Grant
Sarah S Grant
VP Clinical Development, Respiratory and Immunology
在 astrazeneca.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response
SS Grant, DT Hung
Virulence 4 (4), 273-283, 2013
4172013
Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening
SA Stanley, SS Grant, T Kawate, N Iwase, M Shimizu, C Wivagg, M Silvis, ...
ACS chemical biology 7 (8), 1377-1384, 2012
3122012
Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals
SS Grant, BB Kaufmann, NS Chand, N Haseley, DT Hung
Proceedings of the National Academy of Sciences 109 (30), 12147-12152, 2012
3112012
COPDGene® 2019: redefining the diagnosis of chronic obstructive pulmonary disease
KE Lowe, EA Regan, A Anzueto, E Austin, JHM Austin, TH Beaty, ...
Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation 6 (5 …, 2019
2212019
Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32
SA Stanley, T Kawate, N Iwase, M Shimizu, AE Clatworthy, ...
Proceedings of the National Academy of Sciences 110 (28), 11565-11570, 2013
1162013
Interacting Components of the Flagellar Motor ofEscherichia coliRevealed by the Two-hybrid System in Yeast
DL Marykwas, SA Schmidt, HC Berg
Journal of molecular biology 256 (3), 564-576, 1996
1061996
Identification of novel inhibitors of nonreplicating Mycobacterium tuberculosis using a carbon starvation model
SS Grant, T Kawate, PP Nag, MR Silvis, K Gordon, SA Stanley, ...
ACS chemical biology 8 (10), 2224-2234, 2013
932013
Structure-Function Analysis of BfpB, a Secretin-Like Protein Encoded by the Bundle-Forming-Pilus Operon of EnteropathogenicEscherichia coli
SA Schmidt, D Bieber, SW Ramer, J Hwang, CY Wu, G Schoolnik
Journal of bacteriology 183 (16), 4848-4859, 2001
842001
The Type IV Pilus Assembly Complex: Biogenic Interactions among the Bundle-Forming Pilus Proteins of Enteropathogenic Escherichia coli
SW Ramer, GK Schoolnik, CY Wu, J Hwang, SA Schmidt, D Bieber
Journal of bacteriology 184 (13), 3457-3465, 2002
812002
Baeyer-Villiger monooxygenases EthA and MymA are required for activation of replicating and non-replicating Mycobacterium tuberculosis inhibitors
SS Grant, S Wellington, T Kawate, CA Desjardins, MR Silvis, C Wivagg, ...
Cell chemical biology 23 (6), 666-677, 2016
602016
Efficacy and safety of the CFTR potentiator icenticaftor (QBW251) in COPD: results from a phase 2 randomized trial
SM Rowe, I Jones, MT Dransfield, N Haque, S Gleason, KA Hayes, ...
International journal of chronic obstructive pulmonary disease, 2399-2409, 2020
422020
Inhaled anti-TSLP antibody fragment, ecleralimab, blocks responses to allergen in mild asthma
GM Gauvreau, JM Hohlfeld, JM FitzGerald, LP Boulet, DW Cockcroft, ...
European Respiratory Journal 61 (3), 2023
352023
Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response. Virulence 4: 273–283
SS Grant, DT Hung
302013
Efficacy and safety of an inhaled anti-TSLP antibody fragment in adults with mild atopic asthma
GM Gauvreau, JM Hohlfeld, S Grant, M Jain, M Cabanski, P Pertel, ...
B93. Late Breaking Clinical Trials in Airway Diseases, A4207-A4207, 2020
262020
Late breaking abstract-efficacy of CSJ117 on allergen-induced asthmatic responses in mild atopic asthma patients
G Gauvreau, J Hohlfeld, LP Boulet, D Cockcroft, B Davis, JM Fitzgerald, ...
European Respiratory Journal 56 (suppl 64), 2020
222020
The biological pathways underlying response to anti-IL-17A (AIN457; secukinumab) therapy differ across severe asthmatic patients
E Khokhlovich, S Grant, S Kazani, R Strieter, T Thornton-Wells, J Laramie, ...
Eur Respir J 50 (suppl61), OA2897, 2017
15*2017
Compounds for the treatment of tuberculosis
TA Lewis, S Dandapani, D Hung, B Munoz, P Nag, S Grant, T Kawate
US Patent 10,301,294, 2019
112019
A randomized, placebo controlled 4-week study in COPD of QBW251, a potentiator of the cystic fibrosis transmembrane conductance regulator (CFTR) protein
SM Rowe, N Haque, S Gleason, I Jones, K Kulmatycki, D Rowlands, ...
European Respiratory Journal 52 (suppl 62), 2018
82018
Efficacy of CSJ117 on allergen-induced asthmatic response in mild atopic asthma patients
J Hohlfeld, GM Gauvreau, LP Boulet, DW Cockcroft, BE Davis, ...
Pneumologie 75 (S 01), P683, 2021
22021
Silvis 274 M, Kazyanskaya E, Aquadro J, Golas A, Fitzgerald M, Dai H, Zhang L, Hung DT
SA Stanley, SS Grant, T Kawate, N Iwase, M Shimizu, C Wivagg
22012
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