Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to … S Xia, M Liu, C Wang, W Xu, Q Lan, S Feng, F Qi, L Bao, L Du, S Liu, ... Cell research 30 (4), 343-355, 2020 | 1376 | 2020 |
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein S Xia, Y Zhu, M Liu, Q Lan, W Xu, Y Wu, T Ying, S Liu, Z Shi, S Jiang, L Lu Cellular & molecular immunology 17 (7), 765-767, 2020 | 794 | 2020 |
The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin S Xia, Q Lan, S Su, X Wang, W Xu, Z Liu, Y Zhu, Q Wang, L Lu, S Jiang Signal transduction and targeted therapy 5 (1), 92, 2020 | 327 | 2020 |
Development of oncolytic virotherapy: From genetic modification to combination therapy Q Lan, S Xia, Q Wang, W Xu, H Huang, S Jiang, L Lu Frontiers of Medicine 14, 160-184, 2020 | 50 | 2020 |
Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation S Xia, Q Lan, Y Zhu, C Wang, W Xu, Y Li, L Wang, F Jiao, J Zhou, C Hua, ... Signal Transduction and Targeted Therapy 6 (1), 288, 2021 | 44 | 2021 |
Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant S Xia, JFW Chan, L Wang, F Jiao, KKH Chik, H Chu, Q Lan, W Xu, ... Cell Research 32 (4), 404-406, 2022 | 36 | 2022 |
Potent MERS-CoV fusion inhibitory peptides identified from HR2 domain in spike protein of bat coronavirus HKU4 S Xia, Q Lan, J Pu, C Wang, Z Liu, W Xu, Q Wang, H Liu, S Jiang, L Lu Viruses 11 (1), 56, 2019 | 32 | 2019 |
A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases J Zhou, W Xu, Z Liu, C Wang, S Xia, Q Lan, Y Cai, S Su, J Pu, L Xing, ... Acta Pharmaceutica Sinica B 12 (4), 1652-1661, 2022 | 28 | 2022 |
Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B. 1.1. 7 variant (Alpha) S Xia, Z Wen, L Wang, Q Lan, F Jiao, L Tai, Q Wang, F Sun, S Jiang, L Lu, ... Cell discovery 7 (1), 109, 2021 | 27 | 2021 |
25-Hydroxycholesterol-conjugated EK1 peptide with potent and broad-spectrum inhibitory activity against SARS-CoV-2, its variants of concern, and other human coronaviruses Q Lan, C Wang, J Zhou, L Wang, F Jiao, Y Zhang, Y Cai, L Lu, S Xia, ... International journal of molecular sciences 22 (21), 11869, 2021 | 18 | 2021 |
Inefficiency of sera from mice treated with pseudotyped SARS-CoV to neutralize 2019-nCoV infection Z Liu, S Xia, X Wang, Q Lan, W Xu, Q Wang, S Jiang, L Lu Virologica Sinica 35, 340-343, 2020 | 16 | 2020 |
Sodium copper chlorophyllin is highly effective against enterovirus (EV) A71 infection by blocking its entry into the host cell Z Liu, S Xia, X Wang, Q Lan, P Li, W Xu, Q Wang, L Lu, S Jiang ACS Infectious Diseases 6 (5), 882-890, 2020 | 16 | 2020 |
Pan‐coronavirus fusion inhibitors to combat COVID‐19 and other emerging coronavirus infectious diseases Q Lan, L Wang, F Jiao, L Lu, S Xia, S Jiang Journal of Medical Virology 95 (1), e28143, 2023 | 13 | 2023 |
A palmitic acid-conjugated, peptide-based pan-CoV fusion inhibitor potently inhibits infection of SARS-CoV-2 Omicron and other variants of concern Q Lan, JFW Chan, W Xu, L Wang, F Jiao, G Zhang, J Pu, J Zhou, S Xia, ... Viruses 14 (3), 549, 2022 | 13 | 2022 |
The analogs of furanyl methylidene rhodanine exhibit broad-spectrum inhibitory and inactivating activities against enveloped viruses, including SARS-CoV-2 and its variants J Pu, X He, W Xu, C Wang, Q Lan, C Hua, K Wang, L Lu, S Jiang Viruses 14 (3), 489, 2022 | 13 | 2022 |
A bivalent protein targeting glycans and HR1 domain in spike protein potently inhibited infection of SARS-CoV-2 and other human coronaviruses Y Cai, W Xu, J Tang, N Cao, Q Lan, L Lu, S Jiang Cell & Bioscience 11, 1-14, 2021 | 11 | 2021 |
Supercoiling structure-based design of a trimeric coiled-coil peptide with high potency against HIV-1 and human β-coronavirus infection C Wang, S Xia, X Wang, Y Li, H Wang, R Xiang, Q Jiang, Q Lan, R Liang, ... Journal of Medicinal Chemistry 65 (4), 2809-2819, 2021 | 10 | 2021 |
Antigenic mapping reveals sites of vulnerability on α-HCoV spike protein J Xiang, J Su, Q Lan, W Zhao, Y Zhou, Y Xu, J Niu, S Xia, Q Qi, S Sidhu, ... Communications Biology 5 (1), 1179, 2022 | 4 | 2022 |
Coronavirus entry inhibitors Q Lan, S Xia, L Lu Virus Entry Inhibitors: Stopping the Enemy at the Gate, 101-121, 2022 | 3 | 2022 |
Lipopeptide-based pan-CoV fusion inhibitors potently inhibit HIV-1 infection Q Lan, J Pu, Y Cai, J Zhou, L Wang, F Jiao, W Xu, Q Wang, S Xia, L Lu, ... Microbes and Infection 23 (8), 104840, 2021 | 2 | 2021 |