Structural basis for inhibition of human PNP by immucillin-H WF de Azevedo Jr, F Canduri, DM dos Santos, JH Pereira, MVB Dias, ... Biochemical and biophysical research communications 309 (4), 917-922, 2003 | 91* | 2003 |
Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid JH Pereira, JS De Oliveira, F Canduri, MV Dias, MS Palma, LA Basso, ... Acta Crystallographica Section D: Biological Crystallography 60 (12), 2310-2319, 2004 | 90 | 2004 |
Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis MVB Dias, IB Vasconcelos, AMX Prado, V Fadel, LA Basso Journal of structural biology 159 (3), 369-380, 2007 | 68 | 2007 |
Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir DM dos Santos, F Canduri, JH Pereira, MVB Dias, RG Silva, MA Mendes, ... Biochemical and biophysical research communications 308 (3), 553-559, 2003 | 68 | 2003 |
Chimeric glycosyltransferases for the generation of hybrid glycopeptides AW Truman, MVB Dias, S Wu, TL Blundell, F Huang, JB Spencer Chemistry & biology 16 (6), 676-685, 2009 | 65 | 2009 |
Chorismate synthase: an attractive target for drug development against orphan diseases MV B Dias, F Ely, MS Palma, WF de Azevedo, LA Basso, DS Santos Current drug targets 8 (3), 437-444, 2007 | 61 | 2007 |
Enzymology of pyran ring A formation in salinomycin biosynthesis H Luhavaya, MVB Dias, SR Williams, H Hong, LG de Oliveira, PF Leadlay Angewandte Chemie 127 (46), 13826-13829, 2015 | 55 | 2015 |
Structure of chorismate synthase from Mycobacterium tuberculosis MVB Dias, JC Borges, F Ely, JH Pereira, F Canduri, CHI Ramos, ... Journal of structural biology 154 (2), 130-143, 2006 | 49 | 2006 |
Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis MVB Dias, WC Snee, KM Bromfield, RJ Payne, SK Palaninathan, A Ciulli, ... Biochemical Journal 436 (3), 729-739, 2011 | 48 | 2011 |
Folate biosynthesis pathway: mechanisms and insights into drug design for infectious diseases MV Bertacine Dias, JC Santos, GA Libreros-Zuniga, JA Ribeiro, ... Future Medicinal Chemistry 10 (8), 935-959, 2018 | 47 | 2018 |
Crystal structure of human PNP complexed with guanine WF de Azevedo Jr, F Canduri, DM dos Santos, JH Pereira, MVB Dias, ... Biochemical and biophysical research communications 312 (3), 767-772, 2003 | 45 | 2003 |
Effects of the magnesium and chloride ions and shikimate on the structure of shikimate kinase from Mycobacterium tuberculosis MVB Dias, LM Faím, IB Vasconcelos, JS De Oliveira, LA Basso, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006 | 43 | 2006 |
Mycobacterium tuberculosis dihydrofolate reductase reveals two conformational states and a possible low affinity mechanism to antifolate drugs MVB Dias, P Tyrakis, RR Domingues, AFP Leme, TL Blundell Structure 22 (1), 94-103, 2014 | 36 | 2014 |
Crystal structure of human PNP complexed with hypoxanthine and sulfate ion F Canduri, V Fadel, MVB Dias, LA Basso, MS Palma, DS Santos Biochemical and biophysical research communications 326 (2), 335-338, 2005 | 31 | 2005 |
Structural basis for the activity and substrate specificity of fluoroacetyl-CoA thioesterase FlK MVB Dias, F Huang, DY Chirgadze, M Tosin, D Spiteller, EFV Dry, ... Journal of Biological Chemistry 285 (29), 22495-22504, 2010 | 29 | 2010 |
Molecular models of tryptophan synthase from Mycobacterium tuberculosis complexed with inhibitors MVB Dias, F Canduri, NJF da Silveira, CM Czekster, LA Basso, MS Palma, ... Cell biochemistry and biophysics 44 (3), 375-384, 2006 | 23 | 2006 |
Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3α AM Fala, JF Oliveira, D Adamoski, JA Aricetti, MM Dias, MVB Dias, ... Scientific reports 5 (1), 12698, 2015 | 22 | 2015 |
Unexpected enzyme-catalysed [4+ 2] cycloaddition and rearrangement in polyether antibiotic biosynthesis R Little, FCR Paiva, R Jenkins, H Hong, Y Sun, Y Demydchuk, ... Nature Catalysis 2 (11), 1045-1054, 2019 | 21 | 2019 |
Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis PS Bury, F Huang, S Li, Y Sun, PF Leadlay, MVB Dias ACS Chemical Biology 12 (11), 2779-2787, 2017 | 18 | 2017 |
Discovery of Schaeffer’s Acid Analogues as Lead Structures of Mycobacterium tuberculosis Type II Dehydroquinase Using a Rational Drug Design Approach MF Schmidt, O Korb, NI Howard, MVB Dias, TL Blundell, C Abell ChemMedChem 8 (1), 54-58, 2013 | 17 | 2013 |