| Relaxin family peptides and their receptors RAD Bathgate, ML Halls, ET van der Westhuizen, GE Callander, M Kocan, ... Physiological reviews 93 (1), 405-480, 2013 | 547 | 2013 |
| Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists A Gillis, AB Gondin, A Kliewer, J Sanchez, HD Lim, C Alamein, ... Science signaling 13 (625), eaaz3140, 2020 | 261 | 2020 |
| Regulation by Ca2+-signaling pathways of adenylyl cyclases ML Halls, DMF Cooper Cold Spring Harbor perspectives in biology 3 (1), a004143, 2011 | 228 | 2011 |
| Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ... Science Translational Medicine 9 (392), eaal3447, 2017 | 197 | 2017 |
| Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2 I Mookerjee, TD Hewitson, ML Halls, RJ Summers, ML Mathai, ... The FASEB journal 23 (4), 1219-1229, 2009 | 159 | 2009 |
| Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission RE Yarwood, WL Imlach, TM Lieu, NA Veldhuis, DD Jensen, ... Proceedings of the National Academy of Sciences 114 (46), 12309-12314, 2017 | 156 | 2017 |
| Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome NN Jimenez-Vargas, LA Pattison, P Zhao, TM Lieu, R Latorre, DD Jensen, ... Proceedings of the National Academy of Sciences 115 (31), E7438-E7447, 2018 | 151 | 2018 |
| Relaxin family peptide receptors RXFP1 and RXFP2 modulate cAMP signaling by distinct mechanisms ML Halls, RAD Bathgate, RJ Summers Molecular pharmacology 70 (1), 214-226, 2006 | 144 | 2006 |
| Direct binding between Orai1 and AC8 mediates dynamic interplay between Ca2+ and cAMP signaling D Willoughby, KL Everett, ML Halls, J Pacheco, P Skroblin, L Vaca, ... Science signaling 5 (219), ra29-ra29, 2012 | 139 | 2012 |
| Relaxin family peptide receptors–former orphans reunite with their parent ligands to activate multiple signalling pathways ML Halls, ET van der Westhuizen, RAD Bathgate, RJ Summers British journal of pharmacology 150 (6), 677-691, 2007 | 137 | 2007 |
| International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1 … ML Halls, RAD Bathgate, SW Sutton, TB Dschietzig, RJ Summers Pharmacological Reviews 67 (2), 389-440, 2015 | 134 | 2015 |
| Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy EE To, R Vlahos, R Luong, ML Halls, PC Reading, PT King, C Chan, ... Nature communications 8 (1), 69, 2017 | 133 | 2017 |
| Ligand-dependent modulation of G protein conformation alters drug efficacy SGB Furness, YL Liang, CJ Nowell, ML Halls, PJ Wookey, E Dal Maso, ... Cell 167 (3), 739-749. e11, 2016 | 128 | 2016 |
| Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8) ML Halls, CP Bond, S Sudo, J Kumagai, T Ferraro, S Layfield, ... Journal of Pharmacology and Experimental Therapeutics 313 (2), 677-687, 2005 | 123 | 2005 |
| Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization E Miess, AB Gondin, A Yousuf, R Steinborn, N Mösslein, Y Yang, ... Science signaling 11 (539), eaas9609, 2018 | 116 | 2018 |
| Adenylyl cyclase signalling complexes–Pharmacological challenges and opportunities ML Halls, DMF Cooper Pharmacology & therapeutics 172, 171-180, 2017 | 108 | 2017 |
| β2-Adrenoceptors on tumor cells play a critical role in stress-enhanced metastasis in a mouse model of breast cancer A Chang, CP Le, AK Walker, SJ Creed, CK Pon, S Albold, D Carroll, ... Brain, behavior, and immunity 57, 106-115, 2016 | 97 | 2016 |
| Sub‐picomolar relaxin signalling by a pre‐assembled RXFP1, AKAP79, AC2, β‐arrestin 2, PDE4D3 complex ML Halls, DMF Cooper The EMBO journal 29 (16), 2772-2787, 2010 | 94 | 2010 |
| The β2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasion CK Pon, JR Lane, EK Sloan, ML Halls The FASEB Journal 30 (3), 1144, 2016 | 88 | 2016 |
| β2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion SJ Creed, CP Le, M Hassan, CK Pon, S Albold, KT Chan, ME Berginski, ... Breast cancer research 17, 1-12, 2015 | 87 | 2015 |
Roger SummersEmeritus Professor of Pharmacology, Monash University在 monash.edu 的电子邮件经过验证
