Is the central nervous system a reservoir of HIV-1? LR Gray, M Roche, JK Flynn, SL Wesselingh, PR Gorry, MJ Churchill Current Opinion in HIV and AIDS 9 (6), 552-558, 2014 | 139 | 2014 |
Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy C Devaud, JA Westwood, LB John, JK Flynn, S Paquet-Fifield, ... Molecular Therapy 22 (1), 18-27, 2014 | 137 | 2014 |
Oncolytic virus and anti–4-1BB combination therapy elicits strong antitumor immunity against established cancer LB John, LJ Howland, JK Flynn, AC West, C Devaud, CP Duong, ... Cancer research 72 (7), 1651-1660, 2012 | 117 | 2012 |
Stem memory T cells (TSCM)—their role in cancer and HIV immunotherapies JK Flynn, PR Gorry Clinical & translational immunology 3 (7), e20, 2014 | 111 | 2014 |
A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations M Roche, H Salimi, R Duncan, BL Wilkinson, K Chikere, MS Moore, ... Retrovirology 10, 1-20, 2013 | 89 | 2013 |
Understanding the mechanisms driving the spread of subtype C HIV-1 MJ Gartner, M Roche, MJ Churchill, PR Gorry, JK Flynn EBioMedicine 53, 2020 | 77 | 2020 |
Early IL‐10 predominant responses are associated with progression to chronic hepatitis C virus infection in injecting drug users JK Flynn, GJ Dore, M Hellard, B Yeung, WD Rawlinson, PA White, ... Journal of Viral Hepatitis 18 (8), 549-561, 2011 | 73 | 2011 |
Longitudinal analysis of CCR5 and CXCR4 usage in a cohort of antiretroviral therapy-naive subjects with progressive HIV-1 subtype C infection MR Jakobsen, K Cashin, M Roche, J Sterjovski, A Ellett, K Borm, J Flynn, ... PloS one 8 (6), e65950, 2013 | 41 | 2013 |
Quantifying Susceptibility of CD4+ Stem Memory T-Cells to Infection by Laboratory Adapted and Clinical HIV-1 Strains JK Flynn, G Paukovics, K Cashin, K Borm, A Ellett, M Roche, ... Viruses 6 (2), 709-726, 2014 | 36 | 2014 |
Differences in coreceptor specificity contribute to alternative tropism of HIV-1 subtype C for CD4+T-cell subsets, including stem cell memory T-cells K Cashin, G Paukovics, MR Jakobsen, L Østergaard, MJ Churchill, ... Retrovirology 11, 1-6, 2014 | 33 | 2014 |
Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitrousage of alternative coreceptors during progressive HIV-1 subtype C infection K Cashin, MR Jakobsen, J Sterjovski, M Roche, A Ellett, JK Flynn, K Borm, ... Retrovirology 10, 1-10, 2013 | 32 | 2013 |
The magnitude of HIV-1 resistance to the CCR5 antagonist maraviroc may impart a differential alteration in HIV-1 tropism for macrophages and T-cell subsets JK Flynn, G Paukovics, MS Moore, A Ellett, LR Gray, R Duncan, H Salimi, ... Virology 442 (1), 51-58, 2013 | 28 | 2013 |
Impaired Hepatitis C Virus (HCV)–Specific Interferon-γ Responses in Individuals With HIV Who Acquire HCV Infection: Correlation With CD4+ T-Cell Counts JK Flynn, GJ Dore, G Matthews, M Hellard, B Yeung, WD Rawlinson, ... The Journal of infectious diseases 206 (10), 1568-1576, 2012 | 27 | 2012 |
Maintenance of T h1 hepatitis C virus (HCV)‐specific responses in individuals with acute HCV who achieve sustained virological clearance after treatment JK Flynn, GJ Dore, M Hellard, B Yeung, WD Rawlinson, PA White, ... Journal of gastroenterology and hepatology 28 (11), 1770-1781, 2013 | 24 | 2013 |
Could GILZ be the answer to glucocorticoid toxicity in lupus? JK Flynn, W Dankers, EF Morand Frontiers in immunology 10, 1684, 2019 | 20 | 2019 |
Necrotic cell death increases the release of macrophage migration inhibitory factor by monocytes/macrophages W Dankers, MA Hasnat, V Swann, A Alharbi, JPW Lee, MA Cristofaro, ... Immunology and Cell Biology 98 (9), 782-790, 2020 | 19 | 2020 |
Molecular gymnastics: mechanisms of HIV-1 resistance to CCR5 antagonists and impact on virus phenotypes M Roche, K Borm, J K Flynn, S R Lewin, M J Churchill, P R Gorry Current topics in medicinal chemistry 16 (10), 1091-1106, 2016 | 15 | 2016 |
GILZ regulates the expression of pro-inflammatory cytokines and protects against end-organ damage in a model of lupus C Nataraja, W Dankers, J Flynn, JPW Lee, W Zhu, FB Vincent, LJ Gearing, ... Frontiers in immunology 12, 652800, 2021 | 13 | 2021 |
Analysis of clinical HIV-1 strains with resistance to maraviroc reveals strain-specific resistance mutations, variable degrees of resistance, and minimal cross-resistance to … JK Flynn, P Ellenberg, R Duncan, A Ellett, J Zhou, J Sterjovski, K Cashin, ... AIDS research and human retroviruses 33 (12), 1220-1235, 2017 | 13 | 2017 |
Onset of immunity in salmonids vaccinated by direct immersion with Yersinia ruckeri and Vibrio anguillarum bacterins KA Johnson, JK Flynn, DF Amend Journal of Fish Diseases 5, 197-205, 1982 | 12 | 1982 |