Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution DA Drummond, CO Wilke Cell 134 (2), 341-352, 2008 | 1160 | 2008 |
Why highly expressed proteins evolve slowly DA Drummond, JD Bloom, C Adami, CO Wilke, FH Arnold Proceedings of the National Academy of Sciences 102 (40), 14338-14343, 2005 | 901 | 2005 |
Stress-triggered phase separation is an adaptive, evolutionarily tuned response JA Riback, CD Katanski, JL Kear-Scott, EV Pilipenko, AE Rojek, ... Cell 168 (6), 1028-1040, 2017 | 804 | 2017 |
The evolutionary consequences of erroneous protein synthesis D Allan Drummond, CO Wilke Nature Reviews Genetics 10 (10), 715-724, 2009 | 585 | 2009 |
Reversible, specific, active aggregates of endogenous proteins assemble upon heat stress EWJ Wallace, JL Kear-Scott, EV Pilipenko, MH Schwartz, PR Laskowski, ... Cell 162 (6), 1286-1298, 2015 | 506 | 2015 |
A single determinant dominates the rate of yeast protein evolution DA Drummond, A Raval, CO Wilke Molecular biology and evolution 23 (2), 327-337, 2006 | 471 | 2006 |
Thermodynamic prediction of protein neutrality JD Bloom, JJ Silberg, CO Wilke, DA Drummond, C Adami, FH Arnold Proceedings of the National Academy of Sciences 102 (3), 606-611, 2005 | 399 | 2005 |
Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast KA Geiler-Samerotte, MF Dion, BA Budnik, SM Wang, DL Hartl, ... Proceedings of the National Academy of Sciences 108 (2), 680-685, 2011 | 321 | 2011 |
A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments Y Li, DA Drummond, AM Sawayama, CD Snow, JD Bloom, FH Arnold Nature Biotechnology 25 (9), 1051-1056, 2007 | 215 | 2007 |
Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast G Csárdi, A Franks, DS Choi, EM Airoldi, DA Drummond PLOS Genetics 11 (5), e1005206, 2015 | 205 | 2015 |
Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteins DA Drummond, BL Iverson, G Georgiou, FH Arnold Journal of molecular biology 350 (4), 806-816, 2005 | 204 | 2005 |
Structural determinants of the rate of protein evolution in yeast JD Bloom, DA Drummond, FH Arnold, CO Wilke Molecular biology and evolution 23 (9), 1751-1761, 2006 | 192 | 2006 |
Cellular sensing by phase separation: Using the process, not just the products H Yoo, C Triandafillou, DA Drummond Journal of Biological Chemistry 294 (18), 7151-7159, 2019 | 175 | 2019 |
Good codons, bad transcript: large reductions in gene expression and fitness arising from synonymous mutations in a key enzyme D Agashe, NC Martinez-Gomez, DA Drummond, CJ Marx Molecular biology and evolution 30 (3), 549-560, 2013 | 163 | 2013 |
On the conservative nature of intragenic recombination DA Drummond, JJ Silberg, MM Meyer, CO Wilke, FH Arnold Proceedings of the National Academy of Sciences 102 (15), 5380-5385, 2005 | 130 | 2005 |
A nutrient-driven tRNA modification alters translational fidelity and genome-wide protein coding across an animal genus JM Zaborske, VL Bauer DuMont, EWJ Wallace, T Pan, CF Aquadro, ... PLoS biology 12 (12), e1002015, 2014 | 104 | 2014 |
Stressful steps: progress and challenges in understanding stress-induced mRNA condensation and accumulation in stress granules H Glauninger, CJW Hickernell, JAM Bard, DA Drummond Molecular cell 82 (14), 2544-2556, 2022 | 79 | 2022 |
Chaperones directly and efficiently disperse stress-triggered biomolecular condensates H Yoo, JAM Bard, E Pilipenko, DA Drummond Molecular Cell 82 (4), 741–755, 2022 | 78 | 2022 |
Transient intracellular acidification regulates the core transcriptional heat shock response CG Triandafillou, CD Katanski, AR Dinner, DA Drummond Elife 9, e54880, 2020 | 74 | 2020 |
Contact density affects protein evolutionary rate from bacteria to animals T Zhou, DA Drummond, CO Wilke Journal of molecular evolution 66, 395-404, 2008 | 70 | 2008 |