| New 1, 2, 4-triazole-Chalcone hybrids induce Caspase-3 dependent apoptosis in A549 human lung adenocarcinoma cells FF Ahmed, AA Abd El-Hafeez, SH Abbas, D Abdelhamid, M Abdel-Aziz European journal of medicinal chemistry 151, 705-722, 2018 | 82 | 2018 |
| 1, 3, 4-oxadiazole/chalcone hybrids: Design, synthesis, and inhibition of leukemia cell growth and EGFR, Src, IL-6 and STAT3 activities MAA Fathi, AA Abd El-Hafeez, D Abdelhamid, SH Abbas, MM Montano, ... Bioorganic chemistry 84, 150-163, 2019 | 58 | 2019 |
| New quinoline/chalcone hybrids as anti-cancer agents: Design, synthesis, and evaluations of cytotoxicity and PI3K inhibitory activity SH Abbas, AA Abd El-Hafeez, ME Shoman, MM Montano, HA Hassan Bioorganic chemistry 82, 360-377, 2019 | 55 | 2019 |
| New antiproliferative 7-(4-(N-substituted carbamoylmethyl) piperazin-1-yl) derivatives of ciprofloxacin induce cell cycle arrest at G2/M phase HHH Mohammed, AA Abd El-Hafeez, SH Abbas, ESMN Abdelhafez, ... Bioorganic & medicinal chemistry 24 (19), 4636-4646, 2016 | 38 | 2016 |
| The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells IM Sayed, A Chakraborty, AA Abd El-Hafeez, A Sharma, AZ Sahan, ... Cells 9 (9), 1980, 2020 | 34 | 2020 |
| Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3 AAA El-Hafeez, HO Khalifa, EAM Mahdy, V Sharma, T Hosoi, P Ghosh, ... Pharmacological Reports 71, 289-298, 2019 | 31 | 2019 |
| Discovery of antiproliferative and anti-FAK inhibitory activity of 1, 2, 4-triazole derivatives containing acetamido carboxylic acid skeleton M Mustafa, GEDA Abuo-Rahma, AA Abd El-Hafeez, ER Ahmed, ... Bioorganic & medicinal chemistry letters 40, 127965, 2021 | 25 | 2021 |
| New 1, 2, 3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization HHH Mohammed, AA Abd El-Hafeez, K Ebeid, AI Mekkawy, ... Journal of enzyme inhibition and medicinal chemistry 37 (1), 1346-1363, 2022 | 24 | 2022 |
| A first-in-class anticancer dual HDAC2/FAK inhibitors bearing hydroxamates/benzamides capped by pyridinyl-1, 2, 4-triazoles M Mustafa, AA Abd El-Hafeez, D Abdelhamid, GD Katkar, YA Mostafa, ... European journal of medicinal chemistry 222, 113569, 2021 | 22 | 2021 |
| First Report of Multidrug-Resistant Carbapenemase-Producing Bacteria Coharboring mcr-9 Associated with Respiratory Disease Complex in Pets: Potential of … HO Khalifa, AF Oreiby, AA Abd El-Hafeez, T Okanda, A Haque, KS Anwar, ... Antimicrobial agents and chemotherapy 65 (1), 10.1128/aac. 01890-20, 2020 | 21 | 2020 |
| 2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights MM Elbadawi, WM Eldehna, AA Abd El-Hafeez, WR Somaa, A Albohy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 355-378, 2022 | 20 | 2022 |
| Comparative evaluation of five assays for detection of carbapenemases with a proposed scheme for their precise application HO Khalifa, T Okanda, AA Abd El-Hafeez, A Abd El Latif, AGK Habib, ... The Journal of Molecular Diagnostics 22 (9), 1129-1138, 2020 | 18 | 2020 |
| Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer EA Abdelsalam, AA Abd El-Hafeez, WM Eldehna, MA El Hassab, ... Journal of enzyme inhibition and medicinal chemistry 37 (1), 2265-2282, 2022 | 17 | 2022 |
| Melilotus indicus extract induces apoptosis in hepatocellular carcinoma cells via a mechanism involving mitochondria-mediated pathways AA Abd El-Hafeez, HO Khalifa, RA Elgawish, SA Shouman, ... Cytotechnology 70, 831-842, 2018 | 17 | 2018 |
| FAK inhibitors as promising anticancer targets: present and future directions M Mustafa, AA Abd El-Hafeez, DA Abdelhafeez, D Abdelhamid, ... Future Medicinal Chemistry 13 (18), 1559-1590, 2021 | 15 | 2021 |
| Design, synthesis and cytotoxicity evaluation of new 3, 5-disubstituted-2-thioxoimidazolidinones KRA Abdellatif, MM Elbadawi, MT Elsaady, AA Abd El-Hafeez, T Fujimura, ... Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018 | 15 | 2018 |
| Synergistic tumor suppression by a Perilla frutescens-derived methoxyflavanone and anti-cancer tyrosine kinase inhibitors in A549 human lung adenocarcinoma AA Abd El-Hafeez, T Fujimura, R Kamei, N Hirakawa, K Baba, K Ono, ... Cytotechnology 70, 913-919, 2018 | 13 | 2018 |
| A methoxyflavanone derivative from the Asian medicinal herb (Perilla frutescens) induces p53-mediated G2/M cell cycle arrest and apoptosis in A549 human lung … AA Abd El-Hafeez, T Fujimura, R Kamei, N Hirakawa, K Baba, K Ono, ... Cytotechnology 70, 899-912, 2018 | 11 | 2018 |
| Identification of novel piperazine-tethered phthalazines as selective CDK1 inhibitors endowed with in vitro anticancer activity toward the pancreatic cancer L Akl, AA Abd El-Hafeez, TM Ibrahim, R Salem, HMM Marzouk, ... European Journal of Medicinal Chemistry 243, 114704, 2022 | 10 | 2022 |
| A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding J Ear, AA Abd El-Hafeez, S Roy, T Ngo, N Rajapakse, J Choi, ... Journal of Biological Chemistry 296, 2021 | 10 | 2021 |
