A shortened Barnes maze protocol reveals memory deficits at 4-months of age in the triple-transgenic mouse model of Alzheimer's disease A Attar, T Liu, WTC Chan, J Hayes, M Nejad, KC Lei, G Bitan PloS one 8 (11), e80355, 2013 | 163 | 2013 |
Keeping the wolves at bay: antitoxins of prokaryotic type II toxin-antitoxin systems WT Chan, M Espinosa, CC Yeo Frontiers in molecular biosciences 3, 9, 2016 | 155 | 2016 |
Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae SK Khoo, B Loll, WT Chan, RL Shoeman, L Ngoo, CC Yeo, A Meinhart Journal of Biological Chemistry 282 (27), 19606-19618, 2007 | 134 | 2007 |
One cannot rule them all: Are bacterial toxins-antitoxins druggable? WT Chan, D Balsa, M Espinosa FEMS microbiology reviews 39 (4), 522-540, 2015 | 90 | 2015 |
Toxin-antitoxin genes of the Gram-positive pathogen Streptococcus pneumoniae: so few and yet so many WT Chan, I Moreno-Córdoba, CC Yeo, M Espinosa Microbiology and molecular biology reviews 76 (4), 773-791, 2012 | 87 | 2012 |
The yefM-yoeB Toxin-Antitoxin Systems of Escherichia coli and Streptococcus pneumoniae: Functional and Structural Correlation C Nieto, I Cherny, SK Khoo, MG de Lacoba, WT Chan, CC Yeo, E Gazit, ... Journal of bacteriology 189 (4), 1266-1278, 2007 | 86 | 2007 |
Safety and pharmacological characterization of the molecular tweezer CLR01–a broad-spectrum inhibitor of amyloid proteins’ toxicity A Attar, WTC Chan, FG Klärner, T Schrader, G Bitan BMC Pharmacology and Toxicology 15, 1-14, 2014 | 65 | 2014 |
Genetic Regulation of the yefM-yoeB Toxin-Antitoxin Locus of Streptococcus pneumoniae WT Chan, C Nieto, JA Harikrishna, SK Khoo, RY Othman, M Espinosa, ... Journal of bacteriology 193 (18), 4612-4625, 2011 | 61 | 2011 |
Conditional activation of toxin-antitoxin systems: postsegregational killing and beyond AM Hernández-Arriaga, WT Chan, M Espinosa, R Díaz-Orejas Microbiology spectrum 2 (5), 10.1128/microbiolspec. plas-0009-2013, 2014 | 43 | 2014 |
Functional validation of putative toxin-antitoxin genes from the Gram-positive pathogen Streptococcus pneumoniae: phd-doc is the fourth bona-fide operon WT Chan, CC Yeo, E Sadowy, M Espinosa Frontiers in microbiology 5, 677, 2014 | 42 | 2014 |
The Streptococcus pneumoniae yefM-yoeB and relBE Toxin-Antitoxin Operons Participate in Oxidative Stress and Biofilm Formation WT Chan, M Domenech, I Moreno-Córdoba, V Navarro-Martínez, C Nieto, ... Toxins 10 (9), 378, 2018 | 40 | 2018 |
Heterologous expression of toxins from bacterial toxin-antitoxin systems in eukaryotic cells: strategies and applications CC Yeo, F Abu Bakar, WT Chan, M Espinosa, JA Harikrishna Toxins 8 (2), 49, 2016 | 31 | 2016 |
The Streptococcus pneumoniae pezAT Toxin–Antitoxin System Reduces β-Lactam Resistance and Genetic Competence WT Chan, M Espinosa Frontiers in Microbiology 7, 1322, 2016 | 28 | 2016 |
Purification of telluric acid for SNO+ neutrinoless double-beta decay search S Hans, R Rosero, L Hu, O Chkvorets, WT Chan, S Guan, W Beriguete, ... Nuclear Instruments and Methods in Physics Research Section A: Accelerators …, 2015 | 23 | 2015 |
Toxin-Antitoxin Loci in Streptococcus pneumoniae WT Chan, I Moreno-Córdoba, CC Yeo, M Espinosa Prokaryotic toxin-antitoxins, 315-339, 2013 | 10 | 2013 |
Prokaryotic Toxin-Antitoxins WT Chan, I Moreno-Córdoba, CC Yeo, M Espinosa | 8 | 2013 |
Conditional activation of toxin-antitoxin systems: postsegregational killing and beyond. Microbiol. Spectr. 2: PLAS-0009-2013. doi: 10.1128/microbiolspec AM Hernández-Arriaga, WT Chan, M Espinosa, R Díaz-Orejas PLAS-0009-2013, 2014 | 7 | 2014 |
Type II bacterial toxin–antitoxins: hypotheses, facts, and the newfound plethora of the PezAT system WT Chan, MP Garcillán-Barcia, CC Yeo, M Espinosa FEMS Microbiology Reviews 47 (5), fuad052, 2023 | 3 | 2023 |
Interactions of the Streptococcus pneumoniae Toxin-Antitoxin RelBE Proteins with Their Target DNA I Moreno-Córdoba, WT Chan, C Nieto, M Espinosa Microorganisms 9 (4), 851, 2021 | 2 | 2021 |
Genetic regulation of the yefM-yoeB and pezAT toxin-antitoxin loci of Streptococcus pneumoniae WT Chan Institut Sains Biologi, Fakulti Sains, Universiti Malaya, 2011 | 1 | 2011 |