Synthesis of site-specific antibody-drug conjugates using unnatural amino acids JY Axup, KM Bajjuri, M Ritland, BM Hutchins, CH Kim, SA Kazane, ... Proceedings of the National Academy of Sciences 109 (40), 16101-16106, 2012 | 725 | 2012 |
Restoration of X-ray resistance and V (D) J recombination in mutant cells by Ku cDNA V Smider, WK Rathmell, MR Lieber, G Chu Science 266 (5183), 288-291, 1994 | 422 | 1994 |
Reshaping antibody diversity F Wang, DC Ekiert, I Ahmad, W Yu, Y Zhang, O Bazirgan, A Torkamani, ... Cell 153 (6), 1379-1393, 2013 | 228 | 2013 |
Ku86 defines the genetic defect and restores X-ray resistance and V (D) J recombination to complementation group 5 hamster cell mutants A Errami, V Smider, WK Rathmell, DM He, EA Hendrickson, ... Molecular and cellular biology, 1996 | 209 | 1996 |
Synthesis of bispecific antibodies using genetically encoded unnatural amino acids CH Kim, JY Axup, A Dubrovska, SA Kazane, BA Hutchins, ED Wold, ... Journal of the American Chemical Society 134 (24), 9918-9921, 2012 | 207 | 2012 |
Protein evolution with an expanded genetic code CC Liu, AV Mack, ML Tsao, JH Mills, HS Lee, H Choe, M Farzan, ... Proceedings of the National Academy of Sciences 105 (46), 17688-17693, 2008 | 188 | 2008 |
Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR SA Kazane, D Sok, EH Cho, ML Uson, P Kuhn, PG Schultz, VV Smider Proceedings of the National Academy of Sciences 109 (10), 3731-3736, 2012 | 187 | 2012 |
Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows D Sok, KM Le, M Vadnais, KL Saye-Francisco, JG Jardine, JL Torres, ... Nature 548 (7665), 108-111, 2017 | 171 | 2017 |
Antibody conjugates with unnatural amino acids TJ Hallam, E Wold, A Wahl, VV Smider Molecular pharmaceutics 12 (6), 1848-1862, 2015 | 136 | 2015 |
Self-assembled antibody multimers through peptide nucleic acid conjugation SA Kazane, JY Axup, CH Kim, M Ciobanu, ED Wold, S Barluenga, ... Journal of the American Chemical Society 135 (1), 340-346, 2013 | 109 | 2013 |
A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union RK Grover, X Zhu, T Nieusma, T Jones, I Boero, AS MacLeod, A Mark, ... Science 343 (6171), 656-661, 2014 | 102 | 2014 |
A genetically encoded aza-Michael acceptor for covalent cross-linking of protein–receptor complexes JL Furman, M Kang, S Choi, Y Cao, ED Wold, SB Sun, VV Smider, ... Journal of the American Chemical Society 136 (23), 8411-8417, 2014 | 100 | 2014 |
Site-specific coupling and sterically controlled formation of multimeric antibody fab fragments with unnatural amino acids BM Hutchins, SA Kazane, K Staflin, JS Forsyth, B Felding-Habermann, ... Journal of molecular biology 406 (4), 595-603, 2011 | 96 | 2011 |
The end-joining reaction in V (D) J recombination V Smider, G Chu Seminars in immunology 9 (3), 189-197, 1997 | 96 | 1997 |
Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation F Wang, S Sen, Y Zhang, I Ahmad, X Zhu, IA Wilson, VV Smider, ... Proceedings of the National Academy of Sciences 110 (11), 4261-4266, 2013 | 94 | 2013 |
Bispecific small molecule–antibody conjugate targeting prostate cancer CH Kim, JY Axup, BR Lawson, H Yun, V Tardif, SH Choi, Q Zhou, ... Proceedings of the National Academy of Sciences 110 (44), 17796-17801, 2013 | 90 | 2013 |
Evolution of proteins with genetically encoded “chemical warheads” CC Liu, AV Mack, EM Brustad, JH Mills, D Groff, VV Smider, PG Schultz Journal of the American Chemical Society 131 (28), 9616-9617, 2009 | 90 | 2009 |
Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids J Grünewald, GS Hunt, L Dong, F Niessen, BG Wen, ML Tsao, R Perera, ... Proceedings of the National Academy of Sciences 106 (11), 4337-4342, 2009 | 84 | 2009 |
Immunochemical termination of self-tolerance J Grünewald, ML Tsao, R Perera, L Dong, F Niessen, BG Wen, DM Kubitz, ... Proceedings of the National Academy of Sciences 105 (32), 11276-11280, 2008 | 82 | 2008 |
Structural and genetic diversity in antibody repertoires from diverse species M de Los Rios, MF Criscitiello, VV Smider Current opinion in structural biology 33, 27-41, 2015 | 78 | 2015 |