Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor MF Segura, D Hanniford, S Menendez, L Reavie, X Zou, S Alvarez-Diaz, ... Proceedings of the National Academy of Sciences 106 (6), 1814-1819, 2009 | 656 | 2009 |
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8 A Kapoor, MS Goldberg, LK Cumberland, K Ratnakumar, MF Segura, ... Nature 468 (7327), 1105-1109, 2010 | 465 | 2010 |
miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis A Gaziel-Sovran, MF Segura, R Di Micco, MK Collins, D Hanniford, ... Cancer cell 20 (1), 104-118, 2011 | 385 | 2011 |
BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapy MF Segura, B Fontanals-Cirera, A Gaziel-Sovran, MV Guijarro, ... Cancer research 73 (20), 6264-6276, 2013 | 274 | 2013 |
Melanoma MicroRNA signature predicts post-recurrence survival MF Segura, I Belitskaya-Lévy, AE Rose, J Zakrzewski, A Gaziel, ... Clinical cancer research 16 (5), 1577-1586, 2010 | 239 | 2010 |
Histone variant H2A. Z. 2 mediates proliferation and drug sensitivity of malignant melanoma C Vardabasso, A Gaspar-Maia, D Hasson, S Pünzeler, D Valle-Garcia, ... Molecular cell 59 (1), 75-88, 2015 | 199 | 2015 |
MiR‐182 overexpression in tumourigenesis of high‐grade serous ovarian carcinoma Z Liu, J Liu, MF Segura, C Shao, P Lee, Y Gong, E Hernando, JJ Wei The Journal of pathology 228 (2), 204-215, 2012 | 188 | 2012 |
MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells S Alvarez-Díaz, N Valle, G Ferrer-Mayorga, L Lombardía, M Herrera, ... Human molecular genetics 21 (10), 2157-2165, 2012 | 173 | 2012 |
6‐Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK‐mediated, p53‐independent activation of Bax and PUMA M Gomez‐Lazaro, MF Galindo, CG Concannon, MF Segura, ... Journal of neurochemistry 104 (6), 1599-1612, 2008 | 155 | 2008 |
Reactive oxygen species and p38 mitogen-activated protein kinase activate Bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate M Gomez-Lazaro, MF Galindo, RMMF De Mera, FJ Fernandez-Gómez, ... Molecular pharmacology 71 (3), 736-743, 2007 | 154 | 2007 |
Efficient in vivo microRNA targeting of liver metastasis C Huynh, MF Segura, A Gaziel-Sovran, S Menendez, F Darvishian, ... Oncogene 30 (12), 1481-1488, 2011 | 136 | 2011 |
MicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells J Yu, R Lei, X Zhuang, X Li, G Li, S Lev, MF Segura, X Zhang, G Hu Nature communications 7 (1), 13884, 2016 | 122 | 2016 |
The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-κB signaling C Sole, X Dolcet, MF Segura, H Gutierrez, MT Diaz-Meco, R Gozzelino, ... The Journal of cell biology 167 (3), 479-492, 2004 | 116 | 2004 |
MicroRNA and cutaneous melanoma: from discovery to prognosis and therapy MF Segura, HS Greenwald, D Hanniford, I Osman, E Hernando Carcinogenesis 33 (10), 1823-1832, 2012 | 114 | 2012 |
Lifeguard/neuronal membrane protein 35 regulates Fas ligand‐mediated apoptosis in neurons via microdomain recruitment M Fernández, MF Segura, C Solé, A Colino, JX Comella, V Ceña Journal of neurochemistry 103 (1), 190-203, 2007 | 100 | 2007 |
The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis MF Segura, C Sole, M Pascual, RS Moubarak, MJ Perez-Garcia, ... Journal of Neuroscience 27 (42), 11228-11241, 2007 | 97 | 2007 |
μ-opioid receptor activation prevents apoptosis following serum withdrawal in differentiated SH-SY5Y cells and cortical neurons via phosphatidylinositol 3-kinase M Iglesias, MF Segura, JX Comella, G Olmos Neuropharmacology 44 (4), 482-492, 2003 | 92 | 2003 |
miR-99a reveals two novel oncogenic proteins E2F2 and EMR2 and represses stemness in lung cancer A Feliciano, Y Garcia-Mayea, L Jubierre, C Mir, M Hummel, J Castellvi, ... Cell death & disease 8 (10), e3141-e3141, 2017 | 90 | 2017 |
Reelin induces the detachment of postnatal subventricular zone cells and the expression of the Egr-1 through Erk1/2 activation S Simó, L Pujadas, MF Segura, AL Torre, JA Del Río, JM Ureña, ... Cerebral cortex 17 (2), 294-303, 2007 | 86 | 2007 |
BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways L Jubierre, A Soriano, L Planells-Ferrer, L París-Coderch, SP Tenbaum, ... Oncogene 35 (39), 5179-5190, 2016 | 85 | 2016 |