Hypermutability and mismatch repair deficiency in RER+ tumor cells R Parsons, GM Li, MJ Longley, W Fang, N Papadopoulos, J Jen, ... Cell 75 (6), 1227-1236, 1993 | 1373 | 1993 |
Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells JT Drummond, GM Li, MJ Longley, P Modrich Science 268 (5219), 1909-1912, 1995 | 784 | 1995 |
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. A Kat, WG Thilly, WH Fang, MJ Longley, GM Li, P Modrich Proceedings of the National Academy of Sciences 90 (14), 6424-6428, 1993 | 558 | 1993 |
Mismatch repair deficiency in phenotypically normal human cells R Parsons, GM Li, M Longley, P Modrich, B Liu, T Berk, SR Hamilton, ... Science 268 (5211), 738-740, 1995 | 418 | 1995 |
DNA polymerase γ in mitochondrial DNA replication and repair MA Graziewicz, MJ Longley, WC Copeland Chemical reviews 106 (2), 383-405, 2006 | 352 | 2006 |
DNA polymerase δ is required for human mismatch repair in vitro MJ Longley, AJ Pierce, P Modrich Journal of Biological Chemistry 272 (16), 10917-10921, 1997 | 324 | 1997 |
The fidelity of human DNA polymerase γ with and without exonucleolytic proofreading and the p55 accessory subunit MJ Longley, D Nguyen, TA Kunkel, WC Copeland Journal of Biological Chemistry 276 (42), 38555-38562, 2001 | 302 | 2001 |
The mitochondrial p55 accessory subunit of human DNA polymerase γ enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance SE Lim, MJ Longley, WC Copeland Journal of Biological Chemistry 274 (53), 38197-38203, 1999 | 291 | 1999 |
Mutant POLG2 disrupts DNA polymerase γ subunits and causes progressive external ophthalmoplegia MJ Longley, S Clark, CYW Man, G Hudson, SE Durham, RW Taylor, ... The American Journal of Human Genetics 78 (6), 1026-1034, 2006 | 286 | 2006 |
Identification of 5′-deoxyribose phosphate lyase activity in human DNA polymerase γ and its role in mitochondrial base excision repair in vitro MJ Longley, R Prasad, DK Srivastava, SH Wilson, WC Copeland Proceedings of the National Academy of Sciences 95 (21), 12244-12248, 1998 | 280 | 1998 |
DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity S Song, ZF Pursell, WC Copeland, MJ Longley, TA Kunkel, CK Mathews Proceedings of the National Academy of Sciences 102 (14), 4990-4995, 2005 | 244 | 2005 |
Characterization of the native and recombinant catalytic subunit of human DNA polymerase γ: identification of residues critical for exonuclease activity and dideoxynucleotide … MJ Longley, PA Ropp, SE Lim, WC Copeland Biochemistry 37 (29), 10529-10539, 1998 | 216 | 1998 |
Long patch base excision repair in mammalian mitochondrial genomes B Szczesny, AW Tann, MJ Longley, WC Copeland, S Mitra Journal of Biological Chemistry 283 (39), 26349-26356, 2008 | 189 | 2008 |
Consequences of mutations in human DNA polymerase γ MJ Longley, MA Graziewicz, RJ Bienstock, WC Copeland Gene 354, 125-131, 2005 | 172 | 2005 |
Active site mutation in DNA polymerase γ associated with progressive external ophthalmoplegia causes error-prone DNA synthesis MV Ponamarev, MJ Longley, D Nguyen, TA Kunkel, WC Copeland Journal of Biological Chemistry 277 (18), 15225-15228, 2002 | 169 | 2002 |
The common A467T mutation in the human mitochondrial DNA polymerase (POLG) compromises catalytic efficiency and interaction with the accessory subunit SSL Chan, MJ Longley, WC Copeland Journal of Biological Chemistry 280 (36), 31341-31346, 2005 | 164 | 2005 |
Structure-function defects of human mitochondrial DNA polymerase in autosomal dominant progressive external ophthalmoplegia MA Graziewicz, MJ Longley, RJ Bienstock, M Zeviani, WC Copeland Nature structural & molecular biology 11 (8), 770-776, 2004 | 158 | 2004 |
Mitochondrial genome maintenance in health and disease WC Copeland, MJ Longley DNA repair 19, 190-198, 2014 | 157 | 2014 |
Characterization of the 5′ to 3′ exonuclease associated with Thermus aquaticus DNA polymerase MJ Longley, SE Bennett, DW Mosbaugh Nucleic acids research 18 (24), 7317-7322, 1990 | 132 | 1990 |
POS5 Gene of Saccharomyces cerevisiae Encodes a Mitochondrial NADH Kinase Required for Stability of Mitochondrial DNA MK Strand, GR Stuart, MJ Longley, MA Graziewicz, OC Dominick, ... Eukaryotic Cell 2 (4), 809-820, 2003 | 131 | 2003 |