Nutritional control of gene expression: how mammalian cells respond to amino acid limitation MS Kilberg, YX Pan, H Chen, V Leung-Pineda Annu. Rev. Nutr. 25, 59-85, 2005 | 340 | 2005 |
Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive … H Chen, YX Pan, EE Dudenhausen, MS Kilberg Journal of Biological Chemistry 279 (49), 50829-50839, 2004 | 242 | 2004 |
Gestational high fat diet programs hepatic phosphoenolpyruvate carboxykinase gene expression and histone modification in neonatal offspring rats RS Strakovsky, X Zhang, D Zhou, YX Pan The Journal of physiology 589 (11), 2707-2717, 2011 | 170 | 2011 |
Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic … RS Strakovsky, H Wang, NJ Engeseth, JA Flaws, WG Helferich, YX Pan, ... Toxicology and applied pharmacology 284 (2), 101-112, 2015 | 155 | 2015 |
Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in … S Zhong, CR Fields, N Su, YX Pan, KD Robertson Oncogene 26 (18), 2621-2634, 2007 | 155 | 2007 |
Gestational low protein diet in the rat mediates Igf2 gene expression in male offspring via altered hepatic DNA methylation L Gong, YX Pan, H Chen Epigenetics 5 (7), 619-626, 2010 | 149 | 2010 |
Dietary protein level and stage of development affect expression of an intestinal peptide transporter (cPepT1) in chickens H Chen, YX Pan, EA Wong, KE Webb Jr The Journal of nutrition 135 (2), 193-198, 2005 | 139 | 2005 |
Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple activating transcription factor-3 mRNA species that, when overexpressed in HepG2 cells … YX Pan, H Chen, F Siu, MS Kilberg Journal of Biological Chemistry 278 (40), 38402-38412, 2003 | 120 | 2003 |
Molecular cloning and functional expression of a chicken intestinal peptide transporter (cPepT1) in Xenopus oocytes and Chinese hamster ovary cells H Chen, YX Pan, EA Wong, KE Webb Jr, JR Bloomquist The Journal of nutrition 132 (3), 387-393, 2002 | 119 | 2002 |
Hepatic cellular senescence pathway genes are induced through histone modifications in a diet-induced obese rat model X Zhang, D Zhou, R Strakovsky, Y Zhang, YX Pan American Journal of Physiology-Gastrointestinal and Liver Physiology, 2012 | 117 | 2012 |
Molecular mechanisms underlying the link between diet and DNA methylation FZ Kadayifci, S Zheng, YX Pan International journal of molecular sciences 19 (12), 4055, 2018 | 112 | 2018 |
Correlation between asparaginase sensitivity and asparagine synthetase protein content, but not mRNA, in acute lymphoblastic leukemia cell lines N Su, YX Pan, M Zhou, RC Harvey, SP Hunger, MS Kilberg Pediatric blood & cancer 50 (2), 274-279, 2008 | 108 | 2008 |
Activation of the ATF3 gene through a co-ordinated amino acid-sensing response programme that controls transcriptional regulation of responsive genes following … YX Pan, H Chen, MM Thiaville, MS Kilberg Biochemical Journal 401 (1), 299-307, 2007 | 107 | 2007 |
Expression of a cloned ovine gastrointestinal peptide transporter (oPepT1) in Xenopus oocytes induces uptake of oligopeptides in vitro YX Pan, EA Wong, KE Webb Jr, JR Bloomquist The Journal of nutrition 131 (4), 1264-1270, 2001 | 105 | 2001 |
Early-life nutritional programming of cognition—the fundamental role of epigenetic mechanisms in mediating the relation between early-life environment and learning and memory … L Moody, H Chen, YX Pan Advances in nutrition 8 (2), 337-350, 2017 | 102 | 2017 |
Characterization of the amino acid response element within the human sodium-coupled neutral amino acid transporter 2 (SNAT2) System A transporter gene SS Palii, MM Thiaville, YX Pan, C Zhong, MS Kilberg Biochemical Journal 395 (3), 517-527, 2006 | 94 | 2006 |
Interaction of RNA-binding proteins HuR and AUF1 with the human ATF3 mRNA 3′-untranslated region regulates its amino acid limitation-induced stabilization YX Pan, H Chen, MS Kilberg Journal of Biological Chemistry 280 (41), 34609-34616, 2005 | 91 | 2005 |
Human CCAAT/enhancer-binding protein β gene expression is activated by endoplasmic reticulum stress through an unfolded protein response element downstream of the protein … C Chen, EE Dudenhausen, YX Pan, C Zhong, MS Kilberg Journal of Biological Chemistry 279 (27), 27948-27956, 2004 | 80 | 2004 |
MEK signaling is required for phosphorylation of eIF2α following amino acid limitation of HepG2 human hepatoma cells MM Thiaville, YX Pan, A Gjymishka, C Zhong, RJ Kaufman, MS Kilberg Journal of biological chemistry 283 (16), 10848-10857, 2008 | 72 | 2008 |
Maternal protein restriction during pregnancy induces CCAAT/enhancer-binding protein (C/EBPβ) expression through the regulation of histone modification at its promoter region … S Zheng, M Rollet, YX Pan Epigenetics 6 (2), 161-170, 2011 | 70 | 2011 |