Ring-closing metathesis for the synthesis of substituted indenols, indenones, indanones and indenes: Tandem RCM-dehydrogenative oxidation and RCM-formal redox isomerization EM Coyanis, JL Panayides, MA Fernandes, CB de Koning, ... Journal of organometallic chemistry 691 (24-25), 5222-5239, 2006 | 52 | 2006 |
Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil DG van Greunen, W Cordier, M Nell, C van der Westhuyzen, ... European journal of medicinal chemistry 127, 671-690, 2017 | 49 | 2017 |
Synthesis of Substituted 2, 3‐Dihydro‐1H‐2‐benzazepines and 1, 2‐Dihydroisoquinolines Using an Isomerization‐Ring‐Closing Metathesis Strategy: Scope and Limitations JL Panayides, R Pathak, CB de Koning, WAL van Otterlo European Journal of Organic Chemistry 2007 (29), 4953-4961, 2007 | 37 | 2007 |
Novel N-benzylpiperidine carboxamide derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease DG van Greunen, CJ van der Westhuizen, W Cordier, M Nell, A Stander, ... European journal of medicinal chemistry 179, 680-693, 2019 | 28 | 2019 |
The synthesis of 2-benzazocines using ring-closing metathesis as a key step JL Panayides, R Pathak, H Panagiotopoulos, H Davids, MA Fernandes, ... Tetrahedron 63 (22), 4737-4747, 2007 | 28 | 2007 |
Tandem catalysis: A ring-closing metathesis followed by dehydrogenative oxidation to afford substituted indenones WAL Van Otterlo, EM Coyanis, JL Panayides, CB de Koning, ... Synlett 2005 (03), 501-505, 2005 | 26 | 2005 |
Landscape and opportunities for active pharmaceutical ingredient manufacturing in developing African economies DL Riley, I Strydom, R Chikwamba, JL Panayides Reaction Chemistry & Engineering 4 (3), 457-489, 2019 | 20 | 2019 |
Potential of Essential Oil-Based Anticholinesterase Insecticides against Anopheles Vectors: A Review TA Rants’o, LL Koekemoer, JL Panayides, RL van Zyl Molecules 27 (20), 7026, 2022 | 17 | 2022 |
Synthesis and in vitro growth inhibitory activity of novel silyl-and trityl-modified nucleosides JL Panayides, V Mathieu, LMY Banuls, H Apostolellis, N Dahan-Farkas, ... Bioorganic & medicinal chemistry 24 (12), 2716-2724, 2016 | 16 | 2016 |
Immobilized tetrakis (triphenylphosphine) palladium (0) for Suzuki–Miyaura coupling reactions under flow conditions GV Ramaotsoa, I Strydom, JL Panayides, D Riley Reaction Chemistry & Engineering 4 (2), 372-382, 2019 | 15 | 2019 |
Design, synthesis, and In vitro antituberculosis activity of 2 (5H)‐Furanone derivatives AH Ngwane, JL Panayides, F Chouteau, L Macingwana, A Viljoen, ... IUBMB life 68 (8), 612-620, 2016 | 15 | 2016 |
Aberrant apoptotic response of colorectal cancer cells to novel nucleoside analogues L Harmse, N Dahan-Farkas, JL Panayides, W Van Otterlo, C Penny PloS one 10 (9), e0138607, 2015 | 13 | 2015 |
The synthesis of 5-, 6-, 7-and 8-membered oxygen-containing benzo-fused rings using alkene isomerization and ring-closing metathesis reactions R Pathak, JL Panayides, TD Jeftic, CB De Koning, WAL Van Otterlo South African Journal of Chemistry 60 (1), 1-7, 2007 | 13 | 2007 |
Discovery of Novel Acetylcholinesterase Inhibitors by Virtual Screening, In Vitro Screening, and Molecular Dynamics Simulations CJ van der Westhuizen, A Stander, DL Riley, JL Panayides Journal of Chemical Information and Modeling 62 (6), 1550-1572, 2022 | 9 | 2022 |
N-{3-Isopropoxy-4-methoxy-2-[(E)-1-propenyl] benzyl}(phenyl) methanesulfonamide WAL van Otterlo, JL Panayides, MA Fernandes Acta Crystallographica Section E: Structure Reports Online 60 (9), o1586-o1588, 2004 | 6 | 2004 |
Use of open-source software platform to develop dashboards for control and automation of flow chemistry equipment CJ van der Westhuizen, J du Toit, N Neyt, D Riley, JL Panayides Digital Discovery 1 (5), 596-604, 2022 | 5 | 2022 |
Anti-mycobacterial peroxides: a new class of agents for development against tuberculosis CW Van der Westhuyzen, RK Haynes, JL Panayides, I Wiid, CJ Parkinson Medicinal Chemistry 16 (3), 392-402, 2020 | 5 | 2020 |
Design and testing of an ozonolysis reactor module with on-the-fly ozone degassing under flow conditions NC Neyt, CJ van der Westhuizen, JL Panayides, DL Riley Reaction Chemistry & Engineering 7 (8), 1718-1727, 2022 | 4 | 2022 |
Rapid formation of 2-lithio-1-(triphenylmethyl) imidazole and substitution reactions in flow S Wang, JL Panayides, D Riley, CJ Tighe, K Hellgardt, KKM Hii, PW Miller Reaction Chemistry & Engineering 6 (11), 2018-2023, 2021 | 3 | 2021 |
The in silico and in vitro analysis of donepezil derivatives for Anopheles acetylcholinesterase inhibition TA Rants’o, DG van Greunen, CJ van der Westhuizen, DL Riley, ... Plos one 17 (11), e0277363, 2022 | 2 | 2022 |