| Discovery of a proneurogenic, neuroprotective chemical AA Pieper, S Xie, E Capota, SJ Estill, J Zhong, JM Long, GL Becker, ... Cell 142 (1), 39-51, 2010 | 429 | 2010 |
| Allosteric inhibition of hypoxia inducible factor-2 with small molecules TH Scheuermann, Q Li, HW Ma, J Key, L Zhang, R Chen, JA Garcia, ... Nature chemical biology 9 (4), 271-276, 2013 | 315 | 2013 |
| Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration Y Zhang, A Desai, SY Yang, KB Bae, MI Antczak, SP Fink, S Tiwari, ... Science 348 (6240), aaa2340, 2015 | 286 | 2015 |
| P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage G Wang, T Han, D Nijhawan, P Theodoropoulos, J Naidoo, S Yadavalli, ... Cell 158 (6), 1324-1334, 2014 | 258 | 2014 |
| Development of proneurogenic, neuroprotective small molecules KS MacMillan, J Naidoo, J Liang, L Melito, NS Williams, L Morlock, ... Journal of the American Chemical Society 133 (5), 1428-1437, 2011 | 211 | 2011 |
| Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis R Tesla, HP Wolf, P Xu, J Drawbridge, SJ Estill, P Huntington, ... Proceedings of the National Academy of Sciences 109 (42), 17016-17021, 2012 | 178 | 2012 |
| The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis AK Walker, PD Rivera, Q Wang, JC Chuang, S Tran, ... Molecular psychiatry 20 (4), 500-508, 2015 | 171 | 2015 |
| Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease H De Jesús-Cortés, P Xu, J Drawbridge, SJ Estill, P Huntington, S Tran, ... Proceedings of the National Academy of Sciences 109 (42), 17010-17015, 2012 | 171 | 2012 |
| Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor JL Rogers, L Bayeh, TH Scheuermann, J Longgood, J Key, J Naidoo, ... Journal of medicinal chemistry 56 (4), 1739-1747, 2013 | 140 | 2013 |
| Metabolomics of tomato xylem sap during bacterial wilt reveals Ralstonia solanacearum produces abundant putrescine, a metabolite that accelerates wilt disease TM Lowe‐Power, CG Hendrich, E von Roepenack‐Lahaye, B Li, D Wu, ... Environmental microbiology 20 (4), 1330-1349, 2018 | 129 | 2018 |
| P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury TC Yin, JK Britt, H De Jesús-Cortés, Y Lu, RM Genova, MZ Khan, ... Cell reports 8 (6), 1731-1740, 2014 | 125 | 2014 |
| Small-molecule activation of the TRAIL receptor DR5 in human cancer cells G Wang, X Wang, H Yu, S Wei, N Williams, DL Holmes, R Halfmann, ... Nature chemical biology 9 (2), 84-89, 2013 | 117 | 2013 |
| Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury MO Blaya, HM Bramlett, J Naidoo, AA Pieper, WD Dietrich Journal of neurotrauma 31 (5), 476-486, 2014 | 103 | 2014 |
| Early detection of subclinical visual damage after blast-mediated TBI enables prevention of chronic visual deficit by treatment with P7C3-S243 LM Dutca, SF Stasheff, A Hedberg-Buenz, DS Rudd, N Batra, FR Blodi, ... Investigative ophthalmology & visual science 55 (12), 8330-8341, 2014 | 93 | 2014 |
| Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses P Luthra, J Naidoo, CA Pietzsch, S De, S Khadka, M Anantpadma, ... Antiviral research 158, 288-302, 2018 | 85 | 2018 |
| Discovery of a Neuroprotective Chemical, (S)-N-(3-(3,6-Dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(−)-P7C3-S243], with Improved … J Naidoo, H De Jesus-Cortes, P Huntington, S Estill, LK Morlock, ... Journal of medicinal chemistry 57 (9), 3746-3754, 2014 | 76 | 2014 |
| Protective efficacy of P7C3-S243 in the 6-hydroxydopamine model of Parkinson's disease D Jesús-Cortés, AD Miller, JK Britt, AJ DeMarco, E Stuebing, J Naidoo, ... NPJ Parkinson's disease 1 (1), 1-6, 2015 | 52 | 2015 |
| Spermidine promotes Bacillus subtilis biofilm formation by activating expression of the matrix regulator slrR L Hobley, B Li, JL Wood, SH Kim, J Naidoo, AS Ferreira, M Khomutov, ... Journal of Biological Chemistry 292 (29), 12041-12053, 2017 | 49 | 2017 |
| Pharmacologic rescue of motor and sensory function by the neuroprotective compound P7C3 following neonatal nerve injury SWP Kemp, M Szynkaruk, KN Stanoulis, MD Wood, EH Liu, MP Willand, ... Neuroscience 284, 202-216, 2015 | 49 | 2015 |
| A kinetic study of the reaction of atomic oxygen with SO2 J Naidoo, A Goumri, P Marshall Proceedings of the Combustion Institute 30 (1), 1219-1225, 2005 | 44 | 2005 |
