Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal M Valius, A Kazlauskas Cell 73 (2), 321-334, 1993 | 797 | 1993 |
The CDK inhibitors in cancer research and therapy J Cicenas, M Valius Journal of cancer research and clinical oncology 137, 1409-1418, 2011 | 278 | 2011 |
The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp. A Kazlauskas, GS Feng, T Pawson, M Valius Proceedings of the National Academy of Sciences 90 (15), 6939-6943, 1993 | 274 | 1993 |
Roscovitine in cancer and other diseases J Cicenas, K Kalyan, A Sorokinas, E Stankunas, J Levy, I Meskinyte, ... Annals of translational medicine 3 (10), 2015 | 273 | 2015 |
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor β subunit A Kazlauskas, A Kashishian, JA Cooper, M Valius Molecular and cellular biology 12 (6), 2534-2544, 1992 | 269 | 1992 |
Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor β subunit and are required for binding of phospholipase … M Valius, C Bazenet, A Kazlauskas Molecular and cellular biology 13 (1), 133-143, 1993 | 262 | 1993 |
Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity RA Klinghoffer, B Duckworth, M Valius, L Cantley, A Kazlauskas Molecular and cellular biology 16 (10), 5905-5914, 1996 | 164 | 1996 |
KRAS, NRAS and BRAF mutations in colorectal cancer and melanoma J Cicenas, L Tamosaitis, K Kvederaviciute, R Tarvydas, G Staniute, ... Medical oncology 34, 1-11, 2017 | 152 | 2017 |
Highlights of the latest advances in research on CDK inhibitors J Cicenas, K Kalyan, A Sorokinas, A Jatulyte, D Valiunas, A Kaupinis, ... Cancers 6 (4), 2224-2242, 2014 | 152 | 2014 |
Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation RR Vaillancourt, LE Heasley, J Zamarripa, B Storey, M Valius, ... Molecular and Cellular Biology, 1995 | 129 | 1995 |
APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis M Yokouchi, T Wakioka, H Sakamoto, H Yasukawa, S Ohtsuka, A Sasaki, ... Oncogene 18 (3), 759-767, 1999 | 99 | 1999 |
Platelet-derived growth factor stimulates protein kinase D through the activation of phospholipase Cγ and protein kinase C J Van Lint, Y Ni, M Valius, W Merlevede, JR Vandenheede Journal of Biological Chemistry 273 (12), 7038-7043, 1998 | 94 | 1998 |
Human amniotic fluid mesenchymal stem cells from second‐and third‐trimester amniocentesis: differentiation potential, molecular signature, and proteome analysis J Savickiene, G Treigyte, S Baronaite, G Valiuliene, A Kaupinis, M Valius, ... Stem cells international 2015 (1), 319238, 2015 | 92 | 2015 |
Klebsiella phage vB_KleM-RaK2—A giant singleton virus of the family Myoviridae E Šimoliūnas, L Kaliniene, L Truncaitė, A Zajančkauskaitė, J Staniulis, ... PLoS One 8 (4), e60717, 2013 | 77 | 2013 |
Intracellular distribution of nontargeted quantum dots after natural uptake and microinjection L Damalakiene, V Karabanovas, S Bagdonas, M Valius, R Rotomskis International journal of nanomedicine, 555-568, 2013 | 76 | 2013 |
The GTPase-activating protein of Ras suppresses platelet-derived growth factor β receptor signaling by silencing phospholipase C-γ1 M Valius, JP Secrist, A Kazlauskas Molecular and cellular biology 15 (6), 3058-3071, 1995 | 68 | 1995 |
The post-abscission midbody is an intracellular signaling organelle that regulates cell proliferation E Peterman, P Gibieža, J Schafer, VA Skeberdis, A Kaupinis, M Valius, ... Nature communications 10 (1), 3181, 2019 | 63 | 2019 |
The platelet-derived growth factor β receptor triggers multiple cytoplasmic signaling cascades that arrive at the nucleus as distinguishable inputs JP Montmayeur, M Valius, J Vandenheede, A Kazlauskas Journal of Biological Chemistry 272 (51), 32670-32678, 1997 | 53 | 1997 |
Tailored dual PEGylation of inorganic porous nanocarriers for extremely long blood circulation in vivo T Nissinen, S Nakki, H Laakso, D Kuciauskas, A Kaupinis, MI Kettunen, ... ACS applied materials & interfaces 8 (48), 32723-32731, 2016 | 51 | 2016 |
PLC-γ activation is required for PDGF-βR-mediated mitogenesis and monocytic differentiation of myeloid progenitor cells M Alimandi, MA Heidaran, JS Gutkind, J Zhang, N Ellmore, M Valius, ... Oncogene 15 (5), 585-593, 1997 | 44 | 1997 |