Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes G Lomberk, Y Blum, R Nicolle, A Nair, KS Gaonkar, L Marisa, A Mathison, ... Nature communications 9 (1), 1978, 2018 | 241 | 2018 |
Pancreatic adenocarcinoma therapeutic targets revealed by tumor-stroma cross-talk analyses in patient-derived xenografts R Nicolle, Y Blum, L Marisa, C Loncle, O Gayet, V Moutardier, O Turrini, ... Cell reports 21 (9), 2458-2470, 2017 | 184 | 2017 |
Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis B Bian, S Mongrain, S Cagnol, MJ Langlois, J Boulanger, G Bernatchez, ... Molecular carcinogenesis 55 (5), 671-687, 2016 | 165 | 2016 |
Prognostic significance of circulating PD-1, PD-L1, pan-BTN3As, BTN3A1 and BTLA in patients with pancreatic adenocarcinoma B Bian, D Fanale, N Dusetti, J Roque, S Pastor, AS Chretien, L Incorvaia, ... Oncoimmunology 8 (4), e1561120, 2019 | 127 | 2019 |
Gene expression profiling of patient‐derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ 1: implications for individualized medicine … B Bian, M Bigonnet, O Gayet, C Loncle, A Maignan, M Gilabert, ... EMBO molecular medicine 9 (4), 482-497, 2017 | 71 | 2017 |
Pancreatic cancer organoids for determining sensitivity to bromodomain and extra-terminal inhibitors (BETi) B Bian, NA Juiz, O Gayet, M Bigonnet, N Brandone, J Roques, J Cros, ... Frontiers in Oncology 9, 475, 2019 | 35 | 2019 |
E2F signature is predictive for the pancreatic adenocarcinoma clinical outcome and sensitivity to E2F inhibitors, but not for the response to cytotoxic-based treatments W Lan, B Bian, Y Xia, S Dou, O Gayet, M Bigonnet, P Santofimia-Castaño, ... Scientific Reports 8 (1), 8330, 2018 | 34 | 2018 |
A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT M Barraud, J Garnier, C Loncle, O Gayet, C Lequeue, S Vasseur, B Bian, ... Oncotarget 7 (33), 53783, 2016 | 33 | 2016 |
Functional impact of colorectal cancer-associated mutations in the transcription factor E2F4 MC Paquin, C Leblanc, E Lemieux, B Bian, N Rivard International journal of oncology 43 (6), 2015-2022, 2013 | 20 | 2013 |
Pancreatic adenocarcinoma therapeutic targets revealed by tumor-stroma cross-talk analyses in patient-derived xenografts. Cell Rep. 2017; 21 (9): 2458–70 R Nicolle, Y Blum, L Marisa, C Loncle, O Gayet, V Moutardier, O Turrini, ... | 7 | |
Coupling live-cell imaging and in situ isolation of the same single cell to profile the transient states of predicted drug-tolerant cells B Bian, A Paquet, MJ Arguel, M Meyer, L Peyre, A Chalabi, M Péré, ... STAR protocols 3 (3), 101600, 2022 | 2 | 2022 |
Novel therapeutic targets for pancreatic adenocarcinoma revealed by a multi-omics analysis of patient-derived xenografts R Nicolle, Y Blum, L Marisa, C Loncle, O Gayet, V Moutardier, O Turrini, ... Pancreatology 17 (3), S36, 2017 | 1 | 2017 |
Multiomics assessment of the cancer and stromal compartments of patient-derived pancreatic xenografts reveals clinically-relevant subtypes and novel targeted therapies R Nicolle, Y Blum, L Marisa, C Loncle, O Gayet, V Moutardier, O Turrini, ... Cancer Research 77 (13_Supplement), 4396-4396, 2017 | | 2017 |
Differential Therapy Based on Tumor Heterogeneity in Pancreatic Cancer J Iovanna, B Bian, M Bigonnet, N Dusetti | | 2017 |
Abstract A48: Multi-omics characterization of PDAC subtypes using PDX reveals that epigenetic but not genetic analysis permit a clinically relevant classification R Nicolle, Y Blum, L Marisa, J Garnier, B Bian, C Loncle, M Bigonnet, ... Cancer Research 76 (24_Supplement), A48-A48, 2016 | | 2016 |
Abstract B72: Pancreatic cancer cell drives stroma composition R Nicolle, Y Blum, L Marisa, J Garnier, B Bian, C Loncle, M Bigonnet, ... Cancer Research 76 (24_Supplement), B72-B72, 2016 | | 2016 |
Multi-omics characterization of PDAC subtypes using PDX reveals that epigenetic but not genetic analysis permit a clinically relevant classification R Nicolle, Y Blum, L Marisa, J Garnier, B Bian, C Loncle, M Bigonnet, ... CANCER RESEARCH 76, 2016 | | 2016 |
Le profil d’expression génique préopératoire: un outil nécessaire pour mieux sélectionner les patients avant traitement chirurgical du cancer du pancréas J Garnier, B Bian, V Moutardier, O Turrini, JR Delpero, M Gasmi, ... Journal de Chirurgie Viscérale 153 (4), A6, 2016 | | 2016 |
L'implication de la Protéase À Cystéine Cathepsine B Dans la Tumorigénèse Colorectale B Bian Université de Sherbrooke, 2014 | | 2014 |
The role of cathepsin B in colorectal tumorigenesis B Bian, S Mongrain, F Boudreau, N Rivard Cancer Research 71 (8_Supplement), 1505-1505, 2011 | | 2011 |