Structural analysis and classification of native proteins from E. coli commonly co-purified by immobilised metal affinity chromatography VM Bolanos-Garcia, OR Davies Biochimica et Biophysica Acta (BBA)-General Subjects 1760 (9), 1304-1313, 2006 | 341 | 2006 |
Interaction with the BRCA2 C terminus protects RAD51–DNA filaments from disassembly by BRC repeats OR Davies, L Pellegrini Nature structural & molecular biology 14 (6), 475-483, 2007 | 261 | 2007 |
Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery TL Blundell, BL Sibanda, RW Montalvão, S Brewerton, V Chelliah, ... Philosophical Transactions of the Royal Society B: Biological Sciences 361 …, 2006 | 246 | 2006 |
Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity B Carroll, D Maetzel, ODK Maddocks, G Otten, M Ratcliff, GR Smith, ... Elife 5, e11058, 2016 | 206 | 2016 |
A molecular model for the role of SYCP3 in meiotic chromosome organisation JL Syrjänen, L Pellegrini, OR Davies elife 3, e02963, 2014 | 145 | 2014 |
Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ Y Li, DY Chirgadze, VM Bolanos‐Garcia, BL Sibanda, OR Davies, ... The EMBO journal 27 (1), 290-300, 2008 | 143 | 2008 |
C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility L Gómez-h, N Felipe-Medina, M Sánchez-Martín, OR Davies, I Ramos, ... Nature communications 7 (1), 13298, 2016 | 98 | 2016 |
A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange MKK Shivji, OR Davies, JM Savill, DL Bates, L Pellegrini, ... Nucleic acids research 34 (14), 4000-4011, 2006 | 93 | 2006 |
Structure of an Xrcc4–DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode AS Doré, N Furnham, OR Davies, BL Sibanda, DY Chirgadze, ... DNA repair 5 (3), 362-368, 2006 | 88 | 2006 |
CtIP tetramer assembly is required for DNA-end resection and repair OR Davies, JV Forment, M Sun, R Belotserkovskaya, J Coates, Y Galanty, ... Nature structural & molecular biology 22 (2), 150-157, 2015 | 78 | 2015 |
Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly JM Dunce, OM Dunne, M Ratcliff, C Millán, S Madgwick, I Uson, ... Nature structural & molecular biology 25 (7), 557-569, 2018 | 73 | 2018 |
Structural analysis of the human SYCE2–TEX12 complex provides molecular insights into synaptonemal complex assembly OR Davies, JD Maman, L Pellegrini Open biology 2 (7), 120099, 2012 | 73 | 2012 |
Tcf15 primes pluripotent cells for differentiation OR Davies, CY Lin, A Radzisheuskaya, X Zhou, J Taube, G Blin, ... Cell reports 3 (2), 472-484, 2013 | 69 | 2013 |
SUMO is a pervasive regulator of meiosis NR Bhagwat, SN Owens, M Ito, JV Boinapalli, P Poa, A Ditzel, ... Elife 10, e57720, 2021 | 63 | 2021 |
Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition S D'Arcy, OR Davies, TL Blundell, VM Bolanos-Garcia Journal of Biological Chemistry 285 (19), 14764-14776, 2010 | 50 | 2010 |
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells J Zhang, M Gurusaran, Y Fujiwara, K Zhang, M Echbarthi, E Vorontsov, ... Nature communications 11 (1), 2055, 2020 | 49 | 2020 |
Molecular structure of human synaptonemal complex protein SYCE1 OM Dunne, OR Davies Chromosoma 128 (3), 223-236, 2019 | 45 | 2019 |
Single-molecule observation of DNA compaction by meiotic protein SYCP3 JL Syrjänen, I Heller, A Candelli, OR Davies, EJG Peterman, GJL Wuite, ... Elife 6, e22582, 2017 | 45 | 2017 |
An engineered complement factor H construct for treatment of C3 glomerulopathy Y Yang, H Denton, OR Davies, K Smith-Jackson, H Kerr, AP Herbert, ... Journal of the American Society of Nephrology 29 (6), 1649-1661, 2018 | 43 | 2018 |
Aneuploidy in oocytes is prevented by sustained CDK1 activity through degron masking in cyclin B1 MD Levasseur, C Thomas, OR Davies, JMG Higgins, S Madgwick Developmental cell 48 (5), 672-684. e5, 2019 | 42 | 2019 |