Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation C Chen, EA Rowell, RM Thomas, WW Hancock, AD Wells Journal of Biological Chemistry 281 (48), 36828-36834, 2006 | 286 | 2006 |
Epigenetic remodeling of the IL-2 and IFN-γ loci in memory CD8 T cells is influenced by CD4 T cells JK Northrop, RM Thomas, AD Wells, H Shen The Journal of Immunology 177 (2), 1062-1069, 2006 | 268 | 2006 |
Signals from CD28 induce stable epigenetic modification of the IL-2 promoter RM Thomas, L Gao, AD Wells The Journal of Immunology 174 (8), 4639-4646, 2005 | 152 | 2005 |
Ikaros enforces the costimulatory requirement for IL2 gene expression and is required for anergy induction in CD4+ T lymphocytes RM Thomas, N Chunder, C Chen, SE Umetsu, S Winandy, AD Wells The Journal of Immunology 179 (11), 7305-7315, 2007 | 112 | 2007 |
Mbd2 promotes foxp3 demethylation and T-regulatory-cell function L Wang, Y Liu, R Han, UH Beier, RM Thomas, AD Wells, WW Hancock Molecular and cellular biology 33 (20), 4106-4115, 2013 | 109 | 2013 |
Defective activation of protein kinase C and Ras-ERK pathways limits IL-2 production and proliferation by CD4+ CD25+ regulatory T cells SP Hickman, J Yang, RM Thomas, AD Wells, LA Turka The Journal of Immunology 177 (4), 2186-2194, 2006 | 104 | 2006 |
De novo DNA methylation is required to restrict T helper lineage plasticity RM Thomas, CJ Gamper, BH Ladle, JD Powell, AD Wells Journal of Biological Chemistry 287 (27), 22900-22909, 2012 | 88 | 2012 |
Quantification of trace elements in normal human brain by inductively coupled plasma atomic emission spectrometry MT Rajan, KSJ Rao, BM Mamatha, RV Rao, P Shanmugavelu, RB Menon, ... Journal of the neurological sciences 146 (2), 153-166, 1997 | 88 | 1997 |
Ikaros silences T-bet expression and interferon-γ production during T helper 2 differentiation RM Thomas, C Chen, N Chunder, L Ma, J Taylor, EJ Pearce, AD Wells Journal of Biological Chemistry 285 (4), 2545-2553, 2010 | 80 | 2010 |
Conserved intergenic elements and DNA methylation cooperate to regulate transcription at the il17 locus RM Thomas, H Sai, AD Wells Journal of Biological Chemistry 287 (30), 25049-25059, 2012 | 70 | 2012 |
Ikaros imposes a barrier to CD8+ T cell differentiation by restricting autocrine IL-2 production S O’Brien, RM Thomas, GB Wertheim, F Zhang, H Shen, AD Wells The Journal of Immunology 192 (11), 5118-5129, 2014 | 61 | 2014 |
Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells C Su, ME Johnson, A Torres, RM Thomas, E Manduchi, P Sharma, ... Nature communications 11 (1), 3294, 2020 | 53 | 2020 |
Histopathological changes induced by acute toxicity of mercuric chloride on the epidermis of freshwater catfish—Heteropneustes fossilis (Bloch) MT Rajan, TK Banerjee Ecotoxicology and Environmental safety 22 (2), 139-152, 1991 | 53 | 1991 |
Tim-3+ T-bet+ tumor-specific Th1 cells colocalize with and inhibit development and growth of murine neoplasms WJ Simmons, M Koneru, M Mohindru, R Thomas, S Cutro, P Singh, ... The Journal of Immunology 174 (3), 1405-1415, 2005 | 49 | 2005 |
Regulatory T cells suppress CD4+ T cells through NFAT‐dependent transcriptional mechanisms DS Shin, A Jordan, S Basu, RM Thomas, S Bandyopadhyay, ... EMBO reports 15 (9), 991-999, 2014 | 48 | 2014 |
Toxicity with intravenous injection of crude marijuana extract ND Vaziri, R Thomas, M Sterling, K Seiff, MV Pahl, J Davila, A Wilson Clinical toxicology 18 (3), 353-366, 1981 | 46 | 1981 |
Facilitation of the Cellular Uptake of a Triplex-Forming Oligonucleotide by Novel Polyamine Analogues: Structure− Activity Relationships RM Thomas, T Thomas, M Wada, LH Sigal, A Shirahata, TJ Thomas Biochemistry 38 (40), 13328-13337, 1999 | 40 | 1999 |
Ndfip1 restricts mTORC1 signalling and glycolysis in regulatory T cells to prevent autoinflammatory disease AAK Layman, G Deng, CE O’Leary, S Tadros, RM Thomas, JM Dybas, ... Nature Communications 8 (1), 15677, 2017 | 39 | 2017 |
Superantigen-induced CD4+ T cell tolerance is associated with DNA methylation and histone hypo-acetylation at cytokine gene loci RM Thomas, SJ Saouaf, AD Wells Genes & Immunity 8 (7), 613-618, 2007 | 23 | 2007 |
Appearance of Langerhans Cells in the Epidermis of Tgfb1−/− SCID Mice: Paracrine and Autocrine Effects of Transforming Growth Factor-β1 and-β21 RM Thomas, DV Belsito, C Huang, L Chen, I Ormsby, WJ Simmons, ... Journal of investigative dermatology 117 (6), 1574-1580, 2001 | 21 | 2001 |