Brain somatic mutations in MTOR reveal translational dysregulations underlying intractable focal epilepsy JK Kim, J Cho, SH Kim, HC Kang, DS Kim, VN Kim, JH Lee The Journal of clinical investigation 129 (10), 4207-4223, 2019 | 52 | 2019 |
Mechanistic target of rapamycin pathway in epileptic disorders JK Kim, JH Lee Journal of Korean Neurosurgical Society 62 (3), 272-287, 2019 | 38 | 2019 |
Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA) EG Overbey, K Ryon, JK Kim, BT Tierney, R Klotz, V Ortiz, S Mullane, ... Nature Communications 15 (1), 4964, 2024 | 13 | 2024 |
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight JK Kim, BT Tierney, EG Overbey, E Dantas, M Fuentealba, J Park, ... Nature Communications 15 (1), 4954, 2024 | 8 | 2024 |
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight J Park, EG Overbey, SA Narayanan, JK Kim, BT Tierney, N Damle, ... Nature Communications 15 (1), 4773, 2024 | 8 | 2024 |
Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight BT Tierney, JK Kim, EG Overbey, KA Ryon, J Foox, MA Sierra, ... Nature Microbiology, 1-15, 2024 | 6 | 2024 |
A Second Space Age Spanning Omics, Platforms, and Medicine Across Orbits CE Mason, J Green, KI Adamopoulos, EE Afshin, JJ Baechle, M Basner, ... Nature, 1-4, 2024 | 6 | 2024 |
Secretome profiling captures acute changes in oxidative stress, brain homeostasis and coagulation from spaceflight N Houerbi, J Kim, EG Overbey Nat. Commun 10, 2024 | 6 | 2024 |
Design, synthesis and biological evaluation of novel MDH inhibitors targeting tumor microenvironment S Godesi, JR Han, JK Kim, DI Kwak, J Lee, H Nada, M Kim, HA Yang, ... Pharmaceuticals 16 (5), 683, 2023 | 6 | 2023 |
Spaceflight alters insulin and estrogen signaling pathways BA Mathyk, M Tabetah, R Karim, V Zaksas, JK Kim, I Anu, M Muratani, ... | 6 | 2023 |
Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight F Wu, H Du, E Overbey, JK Kim, P Makhijani, N Martin, CA Lerner, ... Nature Communications 15 (1), 4795, 2024 | 5 | 2024 |
The Space Omics and Medical Atlas (SOMA): A comprehensive data resource and biobank for astronauts EG Overbey, K Ryon, J Kim Nature, 2024 | 5 | 2024 |
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank EG Overbey, JK Kim, BT Tierney, J Park, N Houerbi, AG Lucaci, ... Nature, 1-3, 2024 | 4 | 2024 |
Lethal COVID-19 associates with raas-induced inflammation for multiple organ damage including mediastinal lymph nodes JW Guarnieri, MJ Topper, K Beigel, JA Haltom, A Chadburn, J Frere, J An, ... bioRxiv, 2023.10. 08.561395, 2023 | 4 | 2023 |
Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight JS Garcia-Medina, K Sienkiewicz, SA Narayanan, EG Overbey, ... Precision Clinical Medicine 7 (1), pbae007, 2024 | 3 | 2024 |
More than a feeling: Dermatological changes impacted by spaceflight H Cope, J Elsborg, S Demharter, JT Mcdonald, C Wernecke, ... Research square, 2023 | 3 | 2023 |
Molecular and physiologic changes in the SpaceX Inspiration4 civilian crew CW Jones, EG Overbey, J Lacombe, AJ Ecker, C Meydan, K Ryon, ... Nature, 1-3, 2024 | 2 | 2024 |
Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight N Houerbi, JK Kim, EG Overbey, R Batra, A Schweickart, L Patras, ... Nature Communications 15 (1), 4862, 2024 | 2 | 2024 |
Spaceflight induces changes in gene expression profiles linked to insulin and estrogen BA Mathyk, M Tabetah, R Karim, V Zaksas, JK Kim, RI Anu, M Muratani, ... Communications Biology 7 (1), 692, 2024 | 2 | 2024 |
Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology H Cope, J Elsborg, S Demharter, JT McDonald, C Wernecke, ... Communications Medicine 4 (1), 106, 2024 | 1 | 2024 |