Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation F Filipello, SF You, FS Mirfakhar, S Mahali, B Bollman, M Acquarone, ... Acta Neuropathologica, 1-24, 2023 | 16 | 2023 |
STAT3 promotes CD1d‐mediated lipid antigen presentation by regulating a critical gene in glycosphingolipid biosynthesis AK Iyer, J Liu, RM Gallo, MH Kaplan, RR Brutkiewicz Immunology 146 (3), 444-455, 2015 | 16 | 2015 |
Temporospatial Analysis and New Players in the Immunology of Amyotrophic Lateral Sclerosis AK Iyer, KJ Jones, VM Sanders, CL Walker International journal of molecular sciences 19 (2), 631, 2018 | 9 | 2018 |
Inhibition of CD1d‐mediated antigen presentation by the transforming growth factor‐β/Smad signalling pathway JC Bailey, AK Iyer, GJ Renukaradhya, Y Lin, H Nguyen, RR Brutkiewicz Immunology 143 (4), 679-691, 2014 | 8 | 2014 |
JNK2 modulates the CD1d‐dependent and‐independent activation of iNKT cells J Liu, RM Gallo, MA Khan, AK Iyer, IM Kratzke, RR Brutkiewicz European journal of immunology 49 (2), 255-265, 2019 | 7 | 2019 |
CD4+ T cell expression of the IL-10 receptor is necessary for facial motoneuron survival after axotomy EM Runge, AK Iyer, DO Setter, FM Kennedy, VM Sanders, KJ Jones Journal of Neuroinflammation 17, 1-16, 2020 | 6 | 2020 |
Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling CMK Miguel A. Minaya, Sidhartha Mahali, Abhirami K. Iyer, Abdallah M ... Frontiers in Molecular Biosciences 10, 2023 | 5 | 2023 |
MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state SF You, L Brase, F Filipello, AK Iyer, J Del-Aguila, J He, RDO Albanus, ... medRxiv, 2023 | 4 | 2023 |
Cellular Sources and Neuroprotective Roles of Interleukin-10 in the Facial Motor Nucleus after Axotomy EM Runge, DO Setter, AK Iyer, EJ Regele, FM Kennedy, VM Sanders, ... Cells 11 (19), 3167, 2022 | 3 | 2022 |
A tale of motor neurons and CD4+ T cells: moving forward by looking back AK Iyer, KJ Jones Neural Regeneration Research 12 (4), 562-565, 2017 | 1 | 2017 |
Cell autonomous microglia defects in a stem cell model of frontotemporal dementia AK Iyer, L Vermunt, FS Mirfakhar, M Minaya, M Acquarone, RK Koppisetti, ... medRxiv, 2024 | | 2024 |
Phospholipase D3 drives microglial response to amyloid pathology in Alzheimer’s disease MJ Rosene, E Danhash, SF You, AK Iyer, S Hsu, MA de Sa Lopes, ... Alzheimer's & Dementia 19, e076884, 2023 | | 2023 |
Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice AB Abhirami K. Iyer,Kathleen M. Schoch,Anthony Verbeck,Grant Galasso,Hao ... PLoS ONE 18 (11), 2023 | | 2023 |
Systematic analysis of cellular crosstalk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer’s diseaseRicardo D'Oliveira Albanus, Gina M Finan, Logan … bioRxiv 2022.11.11.516215; doi: https://doi.org/10.1101/2022.11.11.516215, 2023 | | 2023 |
Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation CMK Fabia Filipello, Shih Feng You, Sidhartha Mahali, Abhirami Kannan Iyer ... medRxiv, 2022.07.05.22277068, 2022 | | 2022 |
Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling VOPCMK Miguel A. Minaya, Sidhartha Mahali, Abhirami K. Iyer, Rita Martinez ... medRxiv, https://doi.org/10.1101/2022.06.10.22276, 2022 | | 2022 |
Differentiation of iPSC into Microglia-Like Cells (iMGL) V3 CMK Abhirami Kannan Iyer, Emma Danhash, Fabia Filipello, Jacob Marsh,RJ Martinez protocols.io, 2022 | | 2022 |
Phospholipase D3 contributes to Alzheimer's disease risk via disruption of Aβ clearance and microglia response to amyloid plaques medRxiv https://doi.org/10.1101/2022.01.31.22270175, 2022 | | 2022 |
Targeted Atp1a2 knockdown by antisense oligonucleotides leads to reduced SOD1 aggregation and accelerated disease progression in the SOD1*G93A mouse model of ALS AB Abhirami Kannan Iyer, Kathleen M. Schoch, Anna Oldenborg, Hao Chen, Sarah ... Alzheimer's and Dementia 17 (S9), 2021 | | 2021 |
STAT3 expression in dendritic cells protects mice from colitis by a gut microbiome-dependent mechanism J Liu, KL Szilágyi, ML Capitano, AK Iyer, J He, MR Olson, J Du, ... bioRxiv, 2021.07. 31.453520, 2021 | | 2021 |