M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination VE Miron, A Boyd, JW Zhao, TJ Yuen, JM Ruckh, JL Shadrach, ... Nature neuroscience 16 (9), 1211-1218, 2013 | 1776 | 2013 |
Remyelination in the CNS: from biology to therapy RJM Franklin, C Ffrench-Constant Nature Reviews Neuroscience 9 (11), 839-855, 2008 | 1713 | 2008 |
Single-cell RNA sequencing of microglia throughout the mouse lifespan and in the injured brain reveals complex cell-state changes TR Hammond, C Dufort, L Dissing-Olesen, S Giera, A Young, A Wysoker, ... Immunity 50 (1), 253-271. e6, 2019 | 1649 | 2019 |
Debris clearance by microglia: an essential link between degeneration and regeneration H Neumann, MR Kotter, RJM Franklin Brain 132 (2), 288-295, 2009 | 1254 | 2009 |
Why does remyelination fail in multiple sclerosis? RJM Franklin Nature Reviews Neuroscience 3 (9), 705-714, 2002 | 1021 | 2002 |
Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation MR Kotter, WW Li, C Zhao, RJM Franklin Journal of Neuroscience 26 (1), 328-332, 2006 | 847 | 2006 |
Rejuvenation of regeneration in the aging central nervous system JM Ruckh, JW Zhao, JL Shadrach, P van Wijngaarden, TN Rao, ... Cell stem cell 10 (1), 96-103, 2012 | 728 | 2012 |
CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination M Zawadzka, LE Rivers, SPJ Fancy, C Zhao, R Tripathi, F Jamen, ... Cell stem cell 6 (6), 578-590, 2010 | 680 | 2010 |
The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation FJ Sim, C Zhao, J Penderis, RJM Franklin Journal of Neuroscience 22 (7), 2451-2459, 2002 | 677 | 2002 |
Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS SPJ Fancy, SE Baranzini, C Zhao, DI Yuk, KA Irvine, S Kaing, N Sanai, ... Genes & development 23 (13), 1571-1585, 2009 | 664 | 2009 |
Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis F Mei, SPJ Fancy, YAA Shen, J Niu, C Zhao, B Presley, E Miao, S Lee, ... Nature medicine 20 (8), 954-960, 2014 | 579 | 2014 |
Retinoid X receptor gamma signaling accelerates CNS remyelination JK Huang, AA Jarjour, B Nait Oumesmar, C Kerninon, A Williams, ... Nature neuroscience 14 (1), 45-53, 2011 | 561 | 2011 |
Multiple sclerosis genetics S Sawcer, RJM Franklin, M Ban The Lancet Neurology 13 (7), 700-709, 2014 | 552 | 2014 |
Regenerating CNS myelin—from mechanisms to experimental medicines RJM Franklin, C Ffrench-Constant Nature Reviews Neuroscience 18 (12), 753-769, 2017 | 523 | 2017 |
bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS HA Arnett, SPJ Fancy, JA Alberta, C Zhao, SR Plant, S Kaing, CS Raine, ... Science 306 (5704), 2111-2115, 2004 | 514 | 2004 |
Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency S Shen, J Sandoval, VA Swiss, J Li, J Dupree, RJM Franklin, ... Nature neuroscience 11 (9), 1024-1034, 2008 | 511 | 2008 |
Repair of demyelinated lesions by transplantation of purified 0-2A progenitor cells AK Groves, SC Barnett, RJM Franklin, AJ Crang, M Mayer, WF Blakemore, ... Nature 362 (6419), 453-455, 1993 | 509 | 1993 |
Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system BG Brinkmann, A Agarwal, MW Sereda, AN Garratt, T Müller, H Wende, ... Neuron 59 (4), 581-595, 2008 | 471 | 2008 |
Neuronal vulnerability and multilineage diversity in multiple sclerosis L Schirmer, D Velmeshev, S Holmqvist, M Kaufmann, S Werneburg, ... Nature 573 (7772), 75-82, 2019 | 463 | 2019 |
Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin‐induced demyelination MR Kotter, A Setzu, FJ Sim, N Van Rooijen, RJM Franklin Glia 35 (3), 204-212, 2001 | 451 | 2001 |