High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections L Zhang, K Yan, Y Zhang, R Huang, J Bian, C Zheng, H Sun, Z Chen, ... Proceedings of the National Academy of Sciences 104 (11), 4606-4611, 2007 | 298 | 2007 |
Heterologous expression of bacterial natural product biosynthetic pathways L Huo, JJ Hug, C Fu, X Bian, Y Zhang, R Müller Natural product reports 36 (10), 1412-1436, 2019 | 219 | 2019 |
Novel lipolytic genes from the microbial metagenomic library of the South China Sea marine sediment Y Hu, C Fu, Y Huang, Y Yin, G Cheng, F Lei, NA Lu, J Li, EJ Ashforth, ... FEMS microbiology ecology 72 (2), 228-237, 2010 | 96 | 2010 |
A marine-derived Streptomyces sp. MS449 produces high yield of actinomycin X2 and actinomycin D with potent anti-tuberculosis activity C Chen, F Song, Q Wang, WM Abdel-Mageed, H Guo, C Fu, W Hou, ... Applied microbiology and biotechnology 95, 919-927, 2012 | 82 | 2012 |
The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD C Fu, A Sikandar, J Donner, N Zaburannyi, J Herrmann, M Reck, ... Nature communications 8 (1), 1529, 2017 | 75 | 2017 |
Molecular cloning and characterization of a new cold-active esterase from a deep-sea metagenomic library C Fu, Y Hu, F Xie, H Guo, EJ Ashforth, SW Polyak, B Zhu, L Zhang Applied microbiology and biotechnology 90, 961-970, 2011 | 75 | 2011 |
Bioprospecting for antituberculosis leads from microbial metabolites EJ Ashforth, C Fu, X Liu, H Dai, F Song, H Guo, L Zhang Natural product reports 27 (11), 1709-1719, 2010 | 75 | 2010 |
Biosynthetic studies of telomycin reveal new lipopeptides with enhanced activity C Fu, L Keller, A Bauer, M Brönstrup, A Froidbise, P Hammann, ... Journal of the American Chemical Society 137 (24), 7692-7705, 2015 | 73 | 2015 |
Interrogation of Streptomyces avermitilis for efficient production of avermectins J Chen, M Liu, X Liu, J Miao, C Fu, H Gao, R Müller, Q Zhang, L Zhang Synthetic and Systems Biotechnology 1 (1), 7-16, 2016 | 41 | 2016 |
Construction and preliminary analysis of a deep-sea sediment metagenomic fosmid library from Qiongdongnan Basin, South China Sea Y Hu, C Fu, Y Yin, G Cheng, F Lei, X Yang, J Li, EJ Ashforth, L Zhang, ... Marine biotechnology 12, 719-727, 2010 | 36 | 2010 |
Isolation, Structure Elucidation, and (Bio) Synthesis of Haprolid, a Cell‐Type‐Specific Myxobacterial Cytotoxin H Steinmetz, J Li, C Fu, N Zaburannyi, B Kunze, K Harmrolfs, V Schmitt, ... Angewandte Chemie International Edition 55 (34), 10113-10117, 2016 | 28 | 2016 |
Inactivation of SACE_3446, a TetR family transcriptional regulator, stimulates erythromycin production in Saccharopolyspora erythraea H Wu, Y Wang, L Yuan, Y Mao, W Wang, L Zhu, P Wu, C Fu, R Müller, ... Synthetic and Systems Biotechnology 1 (1), 39-46, 2016 | 25 | 2016 |
Dual-function chromogenic screening-based CRISPR/Cas9 genome editing system for actinomycetes Q Wang, F Xie, Y Tong, R Habisch, B Yang, L Zhang, R Müller, C Fu Applied microbiology and biotechnology 104, 225-239, 2020 | 23 | 2020 |
Solving the Puzzle of One‐Carbon Loss in Ripostatin Biosynthesis C Fu, D Auerbach, Y Li, U Scheid, E Luxenburger, R Garcia, H Irschik, ... Angewandte Chemie International Edition 56 (8), 2192-2197, 2017 | 17 | 2017 |
Discovery and characterization of a myxobacterial lanthipeptide with unique biosynthetic features and anti-inflammatory activity X Wang, X Chen, ZJ Wang, M Zhuang, L Zhong, C Fu, R Garcia, ... Journal of the American Chemical Society 145 (30), 16924-16937, 2023 | 10 | 2023 |
Armeniaspirol antibiotic biosynthesis: chlorination and oxidative dechlorination steps affording spiro [4.4] non‐8‐ene C Fu, F Xie, J Hoffmann, Q Wang, A Bauer, M Brönstrup, T Mahmud, ... ChemBioChem 20 (6), 764-769, 2019 | 10 | 2019 |
Rational design for over-production of desirable microbial metabolites by precision engineering H Gao, X Zhou, Z Gou, Y Zhuo, C Fu, M Liu, F Song, E Ashforth, L Zhang Antonie van Leeuwenhoek 98, 151-163, 2010 | 6 | 2010 |
Persicamidines—Unprecedented sesquarterpenoids with potent antiviral bioactivity against coronaviruses L Keller, E Oueis, A Kaur, N Safaei, SH Kirsch, AP Gunesch, S Haid, ... Angewandte Chemie International Edition 62 (6), e202214595, 2023 | 5 | 2023 |
The Disorazole Z Family of Highly Potent Anticancer Natural Products from Sorangium cellulosum: Structure, Bioactivity, Biosynthesis, and Heterologous Expression Y Gao, J Birkelbach, C Fu, J Herrmann, H Irschik, B Morgenstern, ... Microbiology Spectrum 11 (4), e00730-23, 2023 | 3 | 2023 |
Isolierung, Strukturaufklärung und (Bio‐) Synthese von Haprolid, einem zellspezifisch zytotoxischen myxobakteriellen Makrolidnaturstoff H Steinmetz, J Li, C Fu, N Zaburannyi, B Kunze, K Harmrolfs, V Schmitt, ... Angewandte Chemie 128 (34), 10267-10271, 2016 | 3 | 2016 |