| Structure of the nanobody-stabilized active state of the kappa opioid receptor T Che, S Majumdar, SA Zaidi, P Ondachi, JD McCorvy, S Wang, ... Cell 172 (1), 55-67. e15, 2018 | 365 | 2018 |
| Crystal structure of the Frizzled 4 receptor in a ligand-free state S Yang, Y Wu, TH Xu, PW de Waal, Y He, M Pu, Y Chen, ZJ DeBruine, ... Nature 560 (7720), 666-670, 2018 | 109 | 2018 |
| Harnessing ion-binding sites for GPCR pharmacology B Zarzycka, SA Zaidi, BL Roth, V Katritch Pharmacological reviews 71 (4), 571-595, 2019 | 84 | 2019 |
| Intracellular transfer of Na+ in an active-state G-protein-coupled receptor ON Vickery, CA Carvalheda, SA Zaidi, AV Pisliakov, V Katritch, ... Structure 26 (1), 171-180. e2, 2018 | 81 | 2018 |
| Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site R Uprety, T Che, SA Zaidi, SG Grinnell, BR Varga, A Faouzi, ST Slocum, ... Elife 10, e56519, 2021 | 52 | 2021 |
| Structure-based design of bitopic ligands for the µ-opioid receptor A Faouzi, H Wang, SA Zaidi, JF DiBerto, T Che, Q Qu, MJ Robertson, ... Nature 613 (7945), 767-774, 2023 | 51 | 2023 |
| Design, synthesis, and biological evaluation of 14-heteroaromatic-substituted naltrexone derivatives: pharmacological profile switch from mu opioid receptor selectivity to mu … Y Yuan, SA Zaidi, O Elbegdorj, LCK Aschenbach, G Li, DL Stevens, ... Journal of medicinal chemistry 56 (22), 9156-9169, 2013 | 49 | 2013 |
| Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells L Seidel, B Zarzycka, SA Zaidi, V Katritch, I Coin Elife 6, e27711, 2017 | 48 | 2017 |
| Structure-based discovery of new antagonist and biased agonist chemotypes for the kappa opioid receptor Z Zheng, XP Huang, TJ Mangano, R Zou, X Chen, SA Zaidi, BL Roth, ... Journal of medicinal chemistry 60 (7), 3070-3081, 2017 | 47 | 2017 |
| Dynamic strategic bond analysis yields a ten-step synthesis of 20-nor-Salvinorin A, a potent κ-OR agonist JJ Roach, Y Sasano, CL Schmid, S Zaidi, V Katritch, RC Stevens, ... ACS central science 3 (12), 1329-1336, 2017 | 46 | 2017 |
| Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3, 14β-dihydroxy-4, 5α-epoxy-6α-(isoquinoline-3′-carboxamido) morphinan analogues as opioid … Y Yuan, SA Zaidi, DL Stevens, KL Scoggins, PD Mosier, GE Kellogg, ... Bioorganic & medicinal chemistry 23 (8), 1701-1715, 2015 | 30 | 2015 |
| 5-Hydroxy-2-(2-phenylethyl) chromone (5-HPEC): A novel non-nitrogenous ligand for 5-HT2B receptor DA Williams, SA Zaidi, Y Zhang Bioorganic & medicinal chemistry letters 24 (6), 1489-1492, 2014 | 25 | 2014 |
| Binding mode characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed … SA Zaidi, CK Arnatt, H He, DE Selley, PD Mosier, GE Kellogg, Y Zhang Bioorganic & medicinal chemistry 21 (21), 6405-6413, 2013 | 25 | 2013 |
| Design, syntheses, and characterization of pharmacophore based chemokine receptor CCR5 antagonists as anti prostate cancer agents CK Arnatt, SA Zaidi, Z Zhang, G Li, AC Richardson, JL Ware, Y Zhang European journal of medicinal chemistry 69, 647-658, 2013 | 21 | 2013 |
| Regio-and stereoselective syntheses of the natural product CCR5 antagonist anibamine and its three olefin isomers F Zhang, S Zaidi, KM Haney, GE Kellogg, Y Zhang The Journal of organic chemistry 76 (19), 7945-7952, 2011 | 21 | 2011 |
| Novel Dual-Target μ-Opioid Receptor and Dopamine D3 Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management A Bonifazi, FO Battiti, J Sanchez, SA Zaidi, E Bow, M Makarova, J Cao, ... Journal of medicinal chemistry 64 (11), 7778-7808, 2021 | 18 | 2021 |
| 17-cyclopropylmethyl-3, 14β-dihydroxy-4, 5α-epoxy-6β-(4′-pyridylcarboxamido) morphinan (NAP) modulating the mu opioid receptor in a biased fashion Y Zhang, DA Williams, SA Zaidi, Y Yuan, A Braithwaite, EJ Bilsky, ... ACS chemical neuroscience 7 (3), 297-304, 2016 | 18 | 2016 |
| 6β-N-heterocyclic substituted naltrexamine derivative BNAP: a peripherally selective mixed MOR/KOR ligand DA Williams, Y Zheng, BG David, Y Yuan, SA Zaidi, DL Stevens, ... ACS chemical neuroscience 7 (8), 1120-1129, 2016 | 14 | 2016 |
| Synthesis and Characterization of 5-Hydroxy-2-(2-phenylethyl)chromone (5-HPEC) and Its Analogues as Non-nitrogenous 5-HT2B Ligands DA Williams, SA Zaidi, Y Zhang Journal of natural products 78 (8), 1859-1867, 2015 | 14 | 2015 |
| Binding mode analyses of NAP derivatives as mu opioid receptor selective ligands through docking studies and molecular dynamics simulation H Wang, SA Zaidi, Y Zhang Bioorganic & medicinal chemistry 25 (8), 2463-2471, 2017 | 12 | 2017 |
Vsevolod KatritchUniversity of Southern California在 usc.edu 的电子邮件经过验证
