cGAS-STING signaling regulates initial innate control of cytomegalovirus infection CWJ Lio, B McDonald, M Takahashi, R Dhanwani, N Sharma, J Huang, ... Journal of virology 90 (17), 7789-7797, 2016 | 134 | 2016 |
The receptor LMIR3 negatively regulates mast cell activation and allergic responses by binding to extracellular ceramide K Izawa, Y Yamanishi, A Maehara, M Takahashi, M Isobe, S Ito, A Kaitani, ... Immunity 37 (5), 827-839, 2012 | 118 | 2012 |
Cytosolic sensing of immuno-stimulatory DNA, the enemy within R Dhanwani, M Takahashi, S Sharma Current opinion in immunology 50, 82-87, 2018 | 112 | 2018 |
Eμ/miR-125b transgenic mice develop lethal B-cell malignancies Y Enomoto, J Kitaura, K Hatakeyama, J Watanuki, T Akasaka, N Kato, ... Leukemia 25 (12), 1849-1856, 2011 | 100 | 2011 |
An activating and inhibitory signal from an inhibitory receptor LMIR3/CLM-1: LMIR3 augments lipopolysaccharide response through association with FcRγ in mast cells K Izawa, J Kitaura, Y Yamanishi, T Matsuoka, A Kaitani, M Sugiuchi, ... The Journal of Immunology 183 (2), 925-936, 2009 | 70 | 2009 |
Ceramide-CD300f binding suppresses experimental colitis by inhibiting ATP-mediated mast cell activation T Matsukawa, K Izawa, M Isobe, M Takahashi, A Maehara, Y Yamanishi, ... Gut 65 (5), 777-787, 2016 | 67 | 2016 |
Sphingomyelin and ceramide are physiological ligands for human LMIR3/CD300f, inhibiting FcεRI-mediated mast cell activation K Izawa, M Isobe, T Matsukawa, S Ito, A Maehara, M Takahashi, ... Journal of allergy and clinical immunology 133 (1), 270-273. e7, 2014 | 61 | 2014 |
The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING–IFN-β pathway M Takahashi, CWJ Lio, A Campeau, M Steger, F Ay, M Mann, ... Nature immunology 22 (4), 485-496, 2021 | 58 | 2021 |
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway J Zhang, CM Simpson, J Berner, HB Chong, J Fang, Z Ordulu, ... Cell 186 (11), 2361-2379. e25, 2023 | 46 | 2023 |
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer T Weiss-Sadan, M Ge, M Hayashi, M Gohar, CH Yao, A de Groot, S Harry, ... Cell metabolism 35 (3), 487-503. e7, 2023 | 46 | 2023 |
Human CD300C delivers an Fc receptor-γ-dependent activating signal in mast cells and monocytes and differs from CD300A in ligand recognition M Takahashi, K Izawa, J Kashiwakura, Y Yamanishi, Y Enomoto, ... Journal of Biological Chemistry 288 (11), 7662-7675, 2013 | 37 | 2013 |
A soluble form of LMIR5/CD300b amplifies lipopolysaccharide-induced lethal inflammation in sepsis Y Yamanishi, M Takahashi, K Izawa, M Isobe, S Ito, A Tsuchiya, ... The Journal of Immunology 189 (4), 1773-1779, 2012 | 35 | 2012 |
Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response R Dhanwani, M Takahashi, IT Mathews, C Lenzi, A Romanov, JD Watrous, ... Science Advances 6 (30), eaba3688, 2020 | 32 | 2020 |
Disrupting ceramide-CD300f interaction prevents septic peritonitis by stimulating neutrophil recruitment K Izawa, A Maehara, M Isobe, Y Yasuda, M Urai, Y Hoshino, K Ueno, ... Scientific reports 7 (1), 4298, 2017 | 27 | 2017 |
Characterization of leukocyte mono-immunoglobulin-like receptor 7 (LMIR7)/CLM-3 as an activating receptor: its similarities to and differences from LMIR4/CLM-5 Y Enomoto, Y Yamanishi, K Izawa, A Kaitani, M Takahashi, A Maehara, ... Journal of Biological Chemistry 285 (46), 35274-35283, 2010 | 22 | 2010 |
The CD300e molecule in mice is an immune-activating receptor M Isobe, K Izawa, M Sugiuchi, T Sakanishi, A Kaitani, A Takamori, ... Journal of Biological Chemistry 293 (10), 3793-3805, 2018 | 18 | 2018 |
The phytosphingosine-CD300b interaction promotes zymosan-induced, nitric oxide–dependent neutrophil recruitment M Takahashi, K Izawa, M Urai, Y Yamanishi, A Maehara, M Isobe, ... Science Signaling 12 (564), eaar5514, 2019 | 12 | 2019 |
MicroRNA-125b-1 accelerates a C-terminal mutant of C/EBPα (C/EBPα-Cm)-induced myeloid leukemia Y Enomoto, J Kitaura, M Shimanuki, N Kato, K Nishimura, M Takahashi, ... International journal of hematology 96, 334-341, 2012 | 11 | 2012 |
Leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 is an FcRγ-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells A Kaitani, K Izawa, A Maehara, M Isobe, A Takamori, T Matsukawa, ... Scientific reports 8 (1), 8259, 2018 | 7 | 2018 |
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability M Takahashi, HB Chong, S Zhang, TY Yang, MJ Lazarov, S Harry, ... Cell 187 (10), 2536-2556. e30, 2024 | 6 | 2024 |