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David Gay
David Gay
在 bric.ku.dk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Modulating the therapeutic response of tumours to dietary serine and glycine starvation
ODK Maddocks, D Athineos, EC Cheung, P Lee, T Zhang, ...
Nature 544 (7650), 372-376, 2017
5222017
Mannose impairs tumour growth and enhances chemotherapy
PS Gonzalez, J O’Prey, S Cardaci, VJA Barthet, J Sakamaki, F Beaumatin, ...
Nature 563 (7733), 719-723, 2018
3612018
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer
AK Najumudeen, F Ceteci, SK Fey, G Hamm, RT Steven, H Hall, ...
Nature genetics 53 (1), 16-26, 2021
1502021
Age-associated mitochondrial DNA mutations cause metabolic remodeling that contributes to accelerated intestinal tumorigenesis
ALM Smith, JC Whitehall, C Bradshaw, D Gay, F Robertson, AP Blain, ...
Nature cancer 1 (10), 976-989, 2020
902020
A MYC–GCN2–eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer
S Schmidt, D Gay, FW Uthe, S Denk, M Paauwe, N Matthes, ...
Nature cell biology 21 (11), 1413-1424, 2019
882019
mTORC2 signaling drives the development and progression of pancreatic cancer
DR Driscoll, SA Karim, M Sano, DM Gay, W Jacob, J Yu, Y Mizukami, ...
Cancer research 76 (23), 6911-6923, 2016
882016
Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis
A Greenhough, C Bagley, KJ Heesom, DB Gurevich, D Gay, M Bond, ...
EMBO molecular medicine 10 (11), e8699, 2018
852018
Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer
DM Gay, RA Ridgway, M Müller, MC Hodder, A Hedley, W Clark, ...
Nature communications 10 (1), 723, 2019
822019
Mevalonate pathway provides ubiquinone to maintain pyrimidine synthesis and survival in p53-deficient cancer cells exposed to metabolic stress
I Kaymak, CR Maier, W Schmitz, AD Campbell, B Dankworth, CP Ade, ...
Cancer Research 80 (2), 189-203, 2020
732020
Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells
DJ Huels, L Bruens, MC Hodder, P Cammareri, AD Campbell, ...
Nature communications 9 (1), 1132, 2018
712018
Translational control through ribosome heterogeneity and functional specialization
DM Gay, AH Lund, MD Jansson
Trends in biochemical sciences 47 (1), 66-81, 2022
652022
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression
JRP Knight, C Alexandrou, GL Skalka, N Vlahov, K Pennel, L Officer, ...
Cancer discovery 11 (5), 1228-1247, 2021
572021
Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
JRP Knight, N Vlahov, DM Gay, RA Ridgway, WJ Faller, C Proud, ...
Elife 10, e69729, 2021
192021
ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging
G Snieckute, L Ryder, AC Vind, Z Wu, FS Arendrup, M Stoneley, ...
Science 382 (6675), eadf3208, 2023
172023
The role of WNT pathway mutations in cancer development and an overview of therapeutic options
W Groenewald, AH Lund, DM Gay
Cells 12 (7), 990, 2023
152023
Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions
SJ Häfner, MD Jansson, K Altinel, KL Andersen, Z Abay-Nørgaard, ...
Developmental Cell 58 (17), 1593-1609. e9, 2023
142023
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
J Vande Voorde, RT Steven, AK Najumudeen, CA Ford, A Dexter, ...
Nature metabolism 5 (8), 1303-1318, 2023
142023
A RAC-GEF network critical for early intestinal tumourigenesis
KA Pickering, K Gilroy, JW Cassidy, SK Fey, AK Najumudeen, LB Zeiger, ...
Nature communications 12 (1), 56, 2021
132021
Correction: Corrigendum: Modulating the therapeutic response of tumours to dietary serine and glycine starvation
ODK Maddocks, D Athineos, EC Cheung, P Lee, T Zhang, ...
Nature 548 (7665), 122-122, 2017
72017
β-catenin drives butyrophilin-like molecule loss and γδ T-cell exclusion in colon cancer
T Suzuki, A Kilbey, N Casa-Rodríguez, A Lawlor, A Georgakopoulou, ...
Cancer immunology research 11 (8), 1137-1155, 2023
62023
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