Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut A Bell, J Brunt, E Crost, L Vaux, R Nepravishta, CD Owen, D Latousakis, ... Nature microbiology 4 (12), 2393-2404, 2019 | 115 | 2019 |
Strategies for chemoenzymatic synthesis of carbohydrates W Li, JB McArthur, X Chen Carbohydrate research 472, 86-97, 2019 | 81 | 2019 |
Cobalt-catalyzed decarboxylative 2-benzoylation of oxazoles and thiazoles with α-oxocarboxylic acids K Yang, X Chen, Y Wang, W Li, AA Kadi, HK Fun, H Sun, Y Zhang, G Li, ... The Journal of organic chemistry 80 (21), 11065-11072, 2015 | 73 | 2015 |
A chemical biology solution to problems with studying biologically important but unstable 9-O-acetyl sialic acids Z Khedri, A Xiao, H Yu, CS Landig, W Li, S Diaz, BR Wasik, CR Parrish, ... ACS chemical biology 12 (1), 214-224, 2017 | 43 | 2017 |
A Diazido Mannose Analogue as a Chemoenzymatic Synthon for Synthesizing Di‐N‐acetyllegionaminic Acid‐Containing Glycosides A Santra, A Xiao, H Yu, W Li, Y Li, L Ngo, JB McArthur, X Chen Angewandte Chemie 130 (11), 2979-2983, 2018 | 31 | 2018 |
Chemoenzymatic synthesis of Neu5Ac9NAc-containing α2–3-and α2–6-linked sialosides and their use for sialidase substrate specificity studies W Li, A Xiao, Y Li, H Yu, X Chen Carbohydrate research 451, 51-58, 2017 | 31 | 2017 |
Are sialic acids involved in COVID-19 pathogenesis? C Dhar, A Sasmal, S Diaz, A Verhagen, H Yu, W Li, X Chen, A Varki Glycobiology 31 (9), 1068-1071, 2021 | 24 | 2021 |
Reversible O-Acetyl Migration within the Sialic Acid Side Chain and Its Influence on Protein Recognition Y Ji, A Sasmal, W Li, L Oh, S Srivastava, AA Hargett, BR Wasik, H Yu, ... ACS chemical biology 16 (10), 1951-1960, 2021 | 22 | 2021 |
Facile chemoenzymatic synthesis of Lewis a (Lea) antigen in gram-scale and sialyl Lewis a (sLea) antigens containing diverse sialic acid forms N Tasnima, H Yu, X Yan, W Li, A Xiao, X Chen Carbohydrate research 472, 115-121, 2019 | 22 | 2019 |
A combined NMR, MD and DFT conformational analysis of 9-O-acetyl sialic acid-containing GM3 ganglioside glycan and its 9-N-acetyl mimic W Li, MD Battistel, H Reeves, L Oh, H Yu, X Chen, LP Wang, ... Glycobiology 30 (10), 787-801, 2020 | 20 | 2020 |
Triazole-linked transition state analogs as selective inhibitors against V. cholerae sialidase TJ Slack, W Li, D Shi, JB McArthur, G Zhao, Y Li, A Xiao, Z Khedri, H Yu, ... Bioorganic & medicinal chemistry 26 (21), 5751-5757, 2018 | 20 | 2018 |
Sialidase-catalyzed one-pot multienzyme (OPME) synthesis of sialidase transition-state analogue inhibitors A Xiao, Y Li, X Li, A Santra, H Yu, W Li, X Chen ACS catalysis 8 (1), 43-47, 2018 | 20 | 2018 |
Streptococcus pneumoniae Sialidase SpNanB-Catalyzed One-Pot Multienzyme (OPME) Synthesis of 2,7-Anhydro-Sialic Acids as Selective Sialidase Inhibitors A Xiao, TJ Slack, Y Li, D Shi, H Yu, W Li, Y Liu, X Chen The Journal of organic chemistry 83 (18), 10798-10804, 2018 | 19 | 2018 |
9-Azido-9-deoxy-2, 3-difluorosialic acid as a subnanomolar inhibitor against bacterial sialidases W Li, A Santra, H Yu, TJ Slack, MM Muthana, D Shi, Y Liu, X Chen The Journal of organic chemistry 84 (11), 6697-6708, 2019 | 18 | 2019 |
Directed evolution identifies high-affinity cystine-knot peptide agonists and antagonists of Wnt/β-catenin signaling S Hansen, Y Zhang, S Hwang, A Nabhan, W Li, J Fuhrmann, ... Proceedings of the National Academy of Sciences 119 (46), e2207327119, 2022 | 16 | 2022 |
L. pneumophila CMP-5, 7-di-N-acetyllegionaminic acid synthetase (LpCLS)-involved chemoenzymatic synthesis of sialosides and analogues JB McArthur, A Santra, W Li, AS Kooner, Z Liu, H Yu, X Chen Organic & biomolecular chemistry 18 (4), 738-744, 2020 | 11 | 2020 |
A substrate tagging and two-step enzymatic reaction strategy for large-scale synthesis of 2, 7-anhydro-sialic acid W Li, T Ghosh, Y Bai, A Santra, A Xiao, X Chen Carbohydrate research 479, 41-47, 2019 | 11 | 2019 |
O-Acetyl Migration within the Sialic Acid Side Chain: A Mechanistic Study Using the Ab Initio Nanoreactor L Oh, Y Ji, W Li, A Varki, X Chen, LP Wang Biochemistry 61 (18), 2007-2013, 2022 | 5 | 2022 |
Sialidase inhibitors and preparation thereof X Chen, A Xiao, W Li, LI Xixuan, Y Li, T Slack US Patent 11,325,936, 2022 | | 2022 |
N-acetylated sialic acids and related sialosides X Chen, A Xiao, A Kooner, A Santra, A Varki, H Yu, W Lee-Ping, W Li US Patent App. 17/491,518, 2022 | | 2022 |