| Metabolic modulation of glioblastoma with dichloroacetate ED Michelakis, G Sutendra, P Dromparis, L Webster, A Haromy, E Niven, ... Science translational medicine 2 (31), 31ra34-31ra34, 2010 | 896 | 2010 |
| A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation G Sutendra, A Kinnaird, P Dromparis, R Paulin, TH Stenson, A Haromy, ... Cell 158 (1), 84-97, 2014 | 558 | 2014 |
| The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted S Bonnet, G Rochefort, G Sutendra, SL Archer, A Haromy, L Webster, ... Proceedings of the National Academy of Sciences 104 (27), 11418-11423, 2007 | 446 | 2007 |
| Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology G Sutendra, ED Michelakis Frontiers in oncology 3, 38, 2013 | 295 | 2013 |
| Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension G Sutendra, S Bonnet, G Rochefort, A Haromy, KD Folmes, ... Science translational medicine 2 (44), 44ra58-44ra58, 2010 | 263 | 2010 |
| The metabolic basis of pulmonary arterial hypertension G Sutendra, ED Michelakis Cell metabolism 19 (4), 558-573, 2014 | 261 | 2014 |
| The role of Nogo and the mitochondria–endoplasmic reticulum unit in pulmonary hypertension G Sutendra, P Dromparis, P Wright, S Bonnet, A Haromy, Z Hao, ... Science translational medicine 3 (88), 88ra55-88ra55, 2011 | 240 | 2011 |
| A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary … G Sutendra, P Dromparis, R Paulin, S Zervopoulos, A Haromy, ... Journal of molecular medicine 91, 1315-1327, 2013 | 237 | 2013 |
| Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer G Sutendra, P Dromparis, A Kinnaird, TH Stenson, A Haromy, JMR Parker, ... Oncogene 32 (13), 1638-1650, 2013 | 231 | 2013 |
| Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans R Paulin, P Dromparis, G Sutendra, V Gurtu, S Zervopoulos, L Bowers, ... Cell metabolism 20 (5), 827-839, 2014 | 226 | 2014 |
| Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension P Dromparis, R Paulin, TH Stenson, A Haromy, G Sutendra, ... Circulation 127 (1), 115-125, 2013 | 174 | 2013 |
| Dehydroepiandrosterone reverses systemic vascular remodeling through the inhibition of the Akt/GSK3-β/NFAT axis S Bonnet, R Paulin, G Sutendra, P Dromparis, M Roy, KO Watson, ... Circulation 120 (13), 1231-1240, 2009 | 153 | 2009 |
| A miR-208–Mef2 axis drives the decompensation of right ventricular function in pulmonary hypertension R Paulin, G Sutendra, V Gurtu, P Dromparis, A Haromy, S Provencher, ... Circulation research 116 (1), 56-69, 2015 | 137 | 2015 |
| Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodeling and … P Dromparis, R Paulin, G Sutendra, AC Qi, S Bonnet, ED Michelakis Circulation research 113 (2), 126-136, 2013 | 136 | 2013 |
| Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension G Sutendra, P Dromparis, S Bonnet, A Haromy, MS McMurtry, ... Journal of molecular medicine 89, 771-783, 2011 | 132 | 2011 |
| The role of mitochondria in pulmonary vascular remodeling P Dromparis, G Sutendra, ED Michelakis Journal of molecular medicine 88, 1003-1010, 2010 | 123 | 2010 |
| Epigenetic metabolic reprogramming of right ventricular fibroblasts in pulmonary arterial hypertension: a pyruvate dehydrogenase kinase-dependent shift in mitochondrial … L Tian, D Wu, A Dasgupta, KH Chen, J Mewburn, F Potus, PDA Lima, ... Circulation research 126 (12), 1723-1745, 2020 | 101 | 2020 |
| Pulmonary arterial hypertension: challenges in translational research and a vision for change G Sutendra, ED Michelakis Science translational medicine 5 (208), 208sr5-208sr5, 2013 | 99 | 2013 |
| Mitochondrial HSP90 accumulation promotes vascular remodeling in pulmonary arterial hypertension O Boucherat, T Peterlini, A Bourgeois, V Nadeau, S Breuils-Bonnet, ... American journal of respiratory and critical care medicine 198 (1), 90-103, 2018 | 93 | 2018 |
| Metabolic modulation of clear-cell renal cell carcinoma with dichloroacetate, an inhibitor of pyruvate dehydrogenase kinase A Kinnaird, P Dromparis, B Saleme, V Gurtu, K Watson, R Paulin, ... European urology 69 (4), 734-744, 2016 | 79 | 2016 |
Peter DromparisUniversity of Alberta在 ualberta.ca 的电子邮件经过验证
Peter DromparisUniversity of Alberta在 ualberta.ca 的电子邮件经过验证
John Reyes UssherFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta在 ualberta.ca 的电子邮件经过验证