EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step S Ninagawa, T Okada, Y Sumitomo, Y Kamiya, K Kato, S Horimoto, ... Journal of Cell Biology 206 (3), 347-356, 2014 | 179 | 2014 |
The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and … S Horimoto, S Ninagawa, T Okada, H Koba, T Sugimoto, Y Kamiya, ... Journal of Biological Chemistry 288 (44), 31517-31527, 2013 | 86 | 2013 |
Mechanisms of productive folding and endoplasmic reticulum-associated degradation of glycoproteins and non-glycoproteins S Ninagawa, G George, K Mori Biochimica et biophysica acta (BBA)-General subjects 1865 (3), 129812, 2021 | 68 | 2021 |
UPR transducer BBF2H7 allows export of type II collagen in a cargo-and developmental stage–specific manner T Ishikawa, T Toyama, Y Nakamura, K Tamada, H Shimizu, S Ninagawa, ... Journal of Cell Biology 216 (6), 1761-1774, 2017 | 68 | 2017 |
Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway S Ninagawa, T Okada, Y Sumitomo, S Horimoto, T Sugimoto, T Ishikawa, ... Journal of Cell Biology 211 (4), 775-784, 2015 | 52 | 2015 |
EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD G George, S Ninagawa, H Yagi, T Saito, T Ishikawa, T Sakuma, ... Elife 9, e53455, 2020 | 41 | 2020 |
Direct mapping of additional modifications on phosphorylated O-glycans of α-dystroglycan by mass spectrometry analysis in conjunction with knocking out of causative genes for … H Yagi, CW Kuo, T Obayashi, S Ninagawa, KH Khoo, K Kato Molecular & Cellular Proteomics 15 (11), 3424-3434, 2016 | 39 | 2016 |
SEL1L is required for endoplasmic reticulum-associated degradation of misfolded luminal proteins but not transmembrane proteins in chicken DT40 cell line S Ninagawa, T Okada, S Takeda, K Mori Cell structure and function 36 (2), 187-195, 2011 | 29 | 2011 |
Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes S Ninagawa, S Tada, M Okumura, K Inoguchi, M Kinoshita, S Kanemura, ... Elife 9, e60970, 2020 | 23 | 2020 |
Reinvestigation of disulfide-bonded oligomeric forms of the unfolded protein response transducer ATF6 H Koba, S Jin, N Imada, T Ishikawa, S Ninagawa, T Okada, T Sakuma, ... Cell Structure and Function 45 (1), 9-21, 2020 | 21 | 2020 |
Improved secretion of glycoproteins using an N-glycan-restricted passport sequence tag recognized by cargo receptor H Yagi, M Yagi-Utsumi, R Honda, Y Ohta, T Saito, M Nishio, S Ninagawa, ... Nature Communications 11 (1), 1368, 2020 | 20 | 2020 |
SEL1L-dependent substrates require Derlin2/3 and Herp1/2 for endoplasmic reticulum-associated degradation T Sugimoto, S Ninagawa, S Yamano, T Ishikawa, T Okada, S Takeda, ... Cell structure and function 42 (2), 81-94, 2017 | 17 | 2017 |
Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD G George, S Ninagawa, H Yagi, J Furukawa, N Hashii, A Ishii-Watabe, ... Elife 10, e70357, 2021 | 16 | 2021 |
A motor neuron disease-associated mutation produces non-glycosylated Seipin that induces ER stress and apoptosis by inactivating SERCA2b S Saito, T Ishikawa, S Ninagawa, T Okada, K Mori Elife 11, e74805, 2022 | 5 | 2022 |
Development of a rapid in vivo assay to evaluate the efficacy of IRE1-specific inhibitors of the unfolded protein response using medaka fish B Jin, T Ishikawa, M Taniguchi, S Ninagawa, T Okada, S Kagaya, K Mori Cell Structure and Function 45 (1), 23-31, 2019 | 3 | 2019 |
PNGase sensitivity assay to study the folding status of proteins S Ninagawa, K Mori Bio-protocol 6 (19), e1952-e1952, 2016 | 3 | 2016 |
Trypsin sensitivity assay to study the folding status of proteins S Ninagawa, K Mori Bio-protocol 6 (19), e1953-e1953, 2016 | 3 | 2016 |
UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins S Ninagawa, M Matsuo, D Ying, S Oshita, S Aso, K Matsushita, ... Elife 12, RP93117, 2024 | 1 | 2024 |
Loss of ATF6α in a human carcinoma cell line is compensated not by its paralogue ATF6β but by sustained activation of the IRE1 and PERK arms for tumor growth in nude mice S Jin, B Jin, T Ishikawa, S Ninagawa, T Okada, S Koyasu, H Harada, ... Molecular Biology of the Cell 34 (3), ar20, 2023 | 1 | 2023 |
Mannose trimming mechanism in endoplasmic reticulum-associated degradation of glycoproteins T Okada, S Ninagawa, K Mori Seikagaku. The Journal of Japanese Biochemical Society 88 (2), 257-260, 2016 | 1 | 2016 |